7 completed. 7 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 7 | Completed 7 |
| Phase 1 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
Follow Diastolic Heart Failure: new trials by email Literature Review of Diastolic Heart Failure trials Research Report on Diastolic Heart Failure
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pharmacokinetics, Pharmacodynamics, and Impact of Inorganic Nitrate on Exercise in HFpEF KNO3, KCl - Heart Failure, Diastolic Heart Failure | Phase 2 | Completed | University of Pennsylvania | 12 | 2015-01-01 | 2017-10-03 |
| Ranolazine in Diastolic Heart Failure Ranolazine, Saline 0.9% and placebo tablet - Diastolic Heart Failure | Phase 2 | Completed | Gilead Sciences | 20 | 2010-04-01 | 2012-07-12 |
| Metoprolol XR in Heart Failure With Normal Ejection Fraction Metoprolol XR - Diastolic Heart Failure | Phase 2 | Completed | Post Graduate Institute of Medical Education and Research, Chandigarh | 102 | 2010-01-01 | 2019-03-21 |
| Perhexiline Therapy in Heart Failure With Preserved Ejection Fraction Syndrome Perhexiline, Placebo - Diastolic Heart Failure | Phase 2 | Completed | University of Aberdeen | 70 | 2009-03-01 | 2015-11-05 |
| A Study of the Effectiveness of Sitaxsentan Sodium in Patients With Diastolic Heart Failure Sitexsentin sodium, Placebo - Diastolic Heart Failure | Phase 2 | Completed | Pfizer | 200 | 2006-03-27 | 2023-01-04 |
| Phosphodiesterase-5 (PDE5) Inhibition and Pulmonary Hypertension in Diastolic Heart Failure Sildenafil, Placebo - Pulmonary Hypertension, Diastolic Heart Failure | Phase 2 / Phase 3 | Completed | University of Milan | 44 | 2006-01-01 | 2012-06-15 |
| Study of Nesiritide in Diastolic Heart Failure. neseritide - Diastolic Heart Failure | Phase 1 / Phase 2 | Completed | Massachusetts General Hospital | 20 | 2002-12-01 | 2014-03-26 |
Heart Failure, Diastolic (7) · Heart Failure (2) · Coronary Artery Disease (1) · Hypertension, Pulmonary (1)
Cardiovascular Diseases (7) · Heart Diseases (7) · Heart Failure (5) · Vascular Diseases (2) · Arterial Occlusive Diseases (1) · Arteriosclerosis (1) · Coronary Disease (1) · Hypertension (1) · Lung Diseases (1) · Myocardial Ischemia (1) · Respiratory Tract Diseases (1)
Perhexiline (1) · Potassium Chloride (1) · Ranolazine (1) · Saline Solution (1) · Sildenafil Citrate (1) · Sodium Chloride (1) · potassium nitrate (1)
Gilead Sciences (1) · Massachusetts General Hospital (1) · Pfizer (1) · Post Graduate Institute of Medical Education and Research, Chandigarh (1) · University of Aberdeen (1) · University of Milan (1) · University of Pennsylvania (1)
United States (2) · Canada (1) · Germany (1) · India (1) · United Kingdom (1)
Julio A Chirinos, MD (1) · Lars S. Maier, MD (1) · Marc J S, MD (1) · Michael P Frenneaux, MBBS MD (1) · Samir Malhotra, MD, DM (1)
PMID 21538388, PMID 21709061, PMID 24621836, PMID 24720918, PMID 25495811, PMID 27927683