5 recruiting, 3 unknown, 2 completed, 1 active not recruiting. 7 Phase 2, 3 Phase 1, 1 Not applicable.
Follow Decompensated Liver Cirrhosis: new trials by email Literature Review of Decompensated Liver Cirrhosis trials Research Report on Decompensated Liver Cirrhosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| LEOPARD Prospective Validation Cohort 1 Standardized assessments, guided tumor biopsy and biobanking, Standardized assessments and biobanking - Decompensated Liver Cirrhosis, Primary Biliary Cholangitis | Recruiting | Assistance Publique - Hôpitaux de Paris | 630 | 2026-07-07 | 2026-07-29 | |
| Statin and Beta Blocker Use in Patients With Decompensated Cirrhosis Atorvastatin 20 mg, Placebo - Decompensated Liver Cirrhosis, Cirrhosis | Phase 2 | Recruiting | CAMC Health System | 50 | 2025-09-09 | 2026-02-25 |
| Effect of Single vs Repeated Cycles of a Combination of Granulocyte Colony Stimulating Factor and Darbepoetin vs Standard Medical Treatment on Immunometabolic Profile in Patient With Early Decompensated Cirrhosis. Darbepoetin, G-CSF, Lactulose - Decompensated Liver Cirrhosis | Not applicable | Recruiting | Institute of Liver and Biliary Sciences, India | 60 | 2025-06-04 | 2026-05-22 |
| LEOPARD Training and Validation Data Collection Study Decompensated Liver Cirrhosis, Primary Biliary Cholangitis | Recruiting | Assistance Publique - Hôpitaux de Paris | 4500 | 2025-02-04 | 2026-07-29 | |
| RTX001 Autologous Engineered Macrophages for Liver Cirrhosis RTX001 - End-stage Liver Disease (ESLD), Cirrhosis, Liver | Phase 1 / Phase 2 | Active not recruiting | Resolution Therapeutics Limited | 30 | 2024-10-15 | 2026-10-05 |
| Safety of Umbilical Cord Mesenchymal Stem Cells (UC-MSC) in Patients With Decompensated Hepatitis B Cirrhosis Human Umbilical Cord Mesenchymal Stem Cells - Decompensated Liver Cirrhosis | Phase 1 / Phase 2 | Not yet recruiting | Asia Cell Therapeutics (Shanghai) Co., Ltd. | 18 | 2023-07-30 | 2023-07-17 |
| Effect of Mesenchymal Stem Cells-derived Exosomes in Decompensated Liver Cirrhosis MSC-derived exosomes - Decompensated Liver Cirrhosis | Phase 2 | Unknown | Research Institute for Gastroenterology and Liver Diseases (RIGLD) | 15 | 2023-05-26 | 2023-05-23 |
| TIPS in Patients With Decompensated Liver Cirrhosis TIPS insertion - Decompensated Liver Cirrhosis | Recruiting | Hannover Medical School | 250 | 2019-08-29 | 2025-09-16 | |
| Mesenchymal Stem Cells Treatment for Decompensated Liver Cirrhosis umbilical cord-derived mesenchymal stem cell, Comprehensive treatment - Decompensated Liver Cirrhosis | Phase 2 | Unknown | Beijing 302 Hospital | 200 | 2019-05-20 | 2019-05-10 |
| Clinical Trial of Umbilical Cord Mesenchymal Stem Cell Transfusion in Decompensated Liver Cirrhosis UC-MSC - Decompensated Liver Cirrhosis | Phase 2 | Unknown | Shandong Qilu Stem Cells Engineering Co., Ltd. | 252 | 2018-06-01 | 2018-05-18 |
| An Follow-Up Study of Liver Cirrhosis Mesenchymal Stem Cell - Decompensated Liver Cirrhosis | Completed | Rohto Pharmaceutical Co., Ltd. | 19 | 2018-03-07 | 2023-11-18 | |
| A Study of ADR-001 in Patients With Liver Cirrhosis Mesenchymal stem cell - Decompensated Liver Cirrhosis | Phase 1 / Phase 2 | Completed | Rohto Pharmaceutical Co., Ltd. | 21 | 2017-07-20 | 2023-07-06 |
Liver Cirrhosis (3) · Ascites (2) · Cholangitis, Sclerosing (2) · Fibrosis (2) · Liver Cirrhosis, Biliary (2) · End Stage Liver Disease (1) · Hepatic Encephalopathy (1) · Hypertension, Portal (1) · Jaundice (1) · Liver Diseases (1)
Pathologic Processes (6) · Pathological Conditions, Signs and Symptoms (6) · Digestive System Diseases (5) · Fibrosis (4) · Liver Diseases (4) · Bile Duct Diseases (2) · Biliary Tract Diseases (2) · Cholangitis (2) · Cholestasis (2) · Cholestasis, Intrahepatic (2) · Liver Cirrhosis (2) · Brain Diseases (1) · Brain Diseases, Metabolic (1) · Central Nervous System Diseases (1) · Hepatic Insufficiency (1)
Albumins (1) · Atorvastatin (1) · Darbepoetin alfa (1) · Granulocyte Colony-Stimulating Factor (1) · Lactulose (1)
Assistance Publique - Hôpitaux de Paris (2) · Rohto Pharmaceutical Co., Ltd. (2) · Asia Cell Therapeutics (Shanghai) Co., Ltd. (1) · Beijing 302 Hospital (1) · CAMC Health System (1) · Hannover Medical School (1) · Institute of Liver and Biliary Sciences, India (1) · Research Institute for Gastroenterology and Liver Diseases (RIGLD) (1) · Resolution Therapeutics Limited (1) · Shandong Qilu Stem Cells Engineering Co., Ltd. (1)
Germany (3) · Belgium (2) · France (2) · Italy (2) · Japan (2) · Netherlands (2) · Spain (2) · Austria (1) · China (1) · India (1) · Iran (1) · United Kingdom (1) · United States (1)
Behzad Hatami, MD (1) · Benjamin Maasoumy, PD (1) · Dr Manoj Kumar Sharma, DM (1) · Fu-Sheng Wang (1) · Jingbo Wang (1) · Lungen Lu, MD (1) · Nadeem Anwar, MD (1) · Shuji Terai, MD (1)
PMID 37600959, PMID 40751304, PMID 40782353, PMID 41420273, PMID 42261201