37 recruiting, 25 completed, 13 not yet recruiting, 3 terminated. 26 Not applicable, 10 Phase 2, 3 Early Phase 1, 3 Phase 1, 3 Phase 4.
Follow Cystic Fibrosis (CF): new trials by email Literature Review of Cystic Fibrosis (CF) trials Research Report on Cystic Fibrosis (CF)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD) Endothelial cell collection - Obesity and Obesity-related Medical Conditions, Diabetes | Recruiting | Bettina Mittendorfer | 100 | 2027-01-01 | 2026-05-07 | |
| Type 2 Inflammation in Adults With Cystic Fibrosis Cystic Fibrosis (CF), Type 2 Inflammatory Disorders | Not yet recruiting | University of Virginia | 100 | 2026-11-01 | 2026-10-23 | |
| Nutrition Supplement for Cystic Fibrosis Common form supplementation, Uncommon nutrient supplementation - Cystic Fibrosis (CF) | Not applicable | Not yet recruiting | Ohio State University | 60 | 2026-10-15 | 2026-09-21 |
| SPutum Induction and Nebuliser deviCEs for Patients With CF Sputum induction - Cystic Fibrosis (CF), Cystic Fibrosis Lung Disease | Not applicable | Not yet recruiting | Royal Brompton & Harefield NHS Foundation Trust | 30 | 2026-10-01 | 2026-10-19 |
| A Study to Evaluate Safety and Explore Efficacy of New Lipase NHS7108 in Adult Participants With Exocrine Pancreatic Insufficiency. NHS7108, Zenpep® - Exocrine Pancreatic Insufficiency (EPI), Cystic Fibrosis (CF) | Phase 2 | Recruiting | Aimmune Nestlé Health Science US R&D, LLC | 66 | 2026-10-01 | 2026-10-01 |
| Pharmacokinetics of Elexacaftor/Tezacaftor/Ivacaftor in Cystic Fibrosis Elexacaftor, Tezacaftor, Ivacaftor, Ivacaftor (VX-770) - Cystic Fibrosis (CF) | Phase 4 | Recruiting | Istituto Giannina Gaslini | 50 | 2026-09-18 | 2026-10-14 |
| Rethinking Early Airway Clearence Therapies As-needed hypertonic saline (HS), Twice daily hypertonic saline (HS), As-needed dornase alfa (DA) - Cystic Fibrosis (CF) | Not applicable | Not yet recruiting | Nicole Hamblett | 405 | 2026-09-15 | 2026-07-10 |
| Heart and Blood Vessels Health in People With Cystic Fibrosis Cystic Fibrosis (CF), Cardiovascular (CV) Risk | Not yet recruiting | Liverpool Heart and Chest Hospital NHS Foundation Trust | 32 | 2026-09-01 | 2026-08-14 | |
| Gastrointestinal Response of Pediatric Cystic Fibrosis Patients on Mediterranean Diet Mediterranean diet - Cystic Fibrosis (CF), Cystic Fibrosis Gastrointestinal Disease | Not applicable | Recruiting | Dartmouth-Hitchcock Medical Center | 20 | 2026-09-01 | 2026-07-02 |
| MRI Parameters as Biomarkers in Cystic Fibrosis (FEMPTO) Linaclotide 290 micrograms, Placebo - Cystic Fibrosis (CF) | Not applicable | Not yet recruiting | University of Nottingham | 12 | 2026-09-01 | 2026-08-21 |
| Home Air Pollution in Children With Cystic Fibrosis Study Cystic Fibrosis (CF) | Not yet recruiting | Seattle Children's Hospital | 200 | 2026-09-01 | 2026-06-24 | |
| Bacteriophages for Adults With Cystic Fibrosis and Chronic Achromobacter Lung Infection AchromoPhage - Cystic Fibrosis (CF), Achromobacter Infection | Phase 1 | Recruiting | Ghady Haidar | 12 | 2026-08-20 | 2026-10-08 |
| Verapamil Effect in Cystic Fibrosis-related Dysglycemia Verapamil Hydrochloride - Cystic Fibrosis Related Diabetes, Cystic Fibrosis (CF) | Phase 2 | Not yet recruiting | Rhode Island Hospital | 30 | 2026-08-01 | 2026-07-09 |
| PERCE-MUCO: Perceptions and Expectations of People With Cystic Fibrosis Regarding a Change in Treatment Cystic Fibrosis (CF) | Recruiting | Fondation Ildys | 343 | 2026-07-09 | 2026-10-28 | |
| Autogenic Drainage Versus Mechanical Percussion in Children With Cystic Fibrosis Autogenic Drainage, Mechanical Percussion - Cystic Fibrosis (CF) | Not applicable | Recruiting | Riphah International University | 32 | 2026-06-14 | 2026-07-28 |
| Diagnostic Value of Oropharyngeal Suction and Effect of Respiratory Physiotherapy on the Detection of Microorganisms in the Pediatric Patient Respiratory physiothperapy, Oropharyngeal suction, Oropharyngeal swab - Cystic Fibrosis (CF), Bronchiectasis, Non-Cystic Fibrosis | Not applicable | Recruiting | Corporacion Parc Tauli | 196 | 2026-06-01 | 2026-10-29 |
| Phase 2 Study to Assess the Safety and Efficacy of ANG003 ANG003 Dose A, ANG003 Dose B, Creon - Exocrine Pancreatic Insufficiency (EPI), Cystic Fibrosis (CF) | Phase 2 | Recruiting | Anagram Therapeutics, Inc. | 113 | 2026-04-24 | 2026-10-30 |
| MRI Assessment of Lung Airways in Cystic Fibrosis: Evaluate MRI's Ability to Detect Changes in Airway Structure . Advanced ultrashort echo time (UTE) MRI - Ultrashort echo time (UTE) imaging is a technique that can quickly capture the fast-decaying 1H lung signal., Multiple Breath Wash out (MBW) - Cystic Fibrosis (CF) | Not yet recruiting | The Hospital for Sick Children | 76 | 2026-04-15 | 2026-03-06 | |
| Study to Enable New Diagnostics for Pulmonary Microbes in People With CF Cystic Fibrosis (CF), New Diagnostics | Recruiting | Chris Goss | 300 | 2026-03-30 | 2026-07-02 | |
| Pharmacokinetics of Antibiotics in Patients With Cystic Fibrosis Trated With Elexacaftor/Tezacaftor/Ivacaftor (ETI) No intervention assigned - Cystic Fibrosis (CF), Pulmonary Exacerbation | Recruiting | Fondation Ildys | 30 | 2026-03-19 | 2026-06-05 |
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Cystic Fibrosis (83) · Motor Activity (6) · Exocrine Pancreatic Insufficiency (5) · Anxiety Disorders (3) · Ciliary Motility Disorders (3) · Diabetes Mellitus (3) · Pulmonary Disease, Chronic Obstructive (3) · Asthma (2) · Bronchiectasis (2) · Chronic Disease (2) · Depression (2) · Dyspnea (2) · Fatigue (2) · Mycobacterium Infections, Nontuberculous (2) · Pancreatic Diseases (2)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (83) · Digestive System Diseases (83) · Genetic Diseases, Inborn (83) · Infant, Newborn, Diseases (83) · Lung Diseases (83) · Respiratory Tract Diseases (83) · Pancreatic Diseases (81) · Pathological Conditions, Signs and Symptoms (14) · Behavior (10) · Pathologic Processes (9) · Disease Attributes (7) · Signs and Symptoms (6) · Chronic Disease (5) · Bronchial Diseases (4) · Endocrine System Diseases (4)
elexacaftor, ivacaftor, tezacaftor drug combination (3) · Diet, Mediterranean (2) · Pancrelipase (2) · Albuterol (1) · Blood Specimen Collection (1) · Culture Techniques (1) · Educational Status (1) · Ethinyl Estradiol (1) · Exercise Test (1) · GLPG2222 (1) · Glucose (1) · Glucose Tolerance Test (1) · Health Records, Personal (1) · Hematologic Tests (1) · Insulin (1)
Ain Shams University (3) · Gazi University (3) · Indiana University (3) · Royal Brompton & Harefield NHS Foundation Trust (3) · University of Virginia (3) · Alexander Horsley (2) · Entero Therapeutics (2) · Fondation Ildys (2) · Istituto Giannina Gaslini (2) · Riphah International University (2) · Sionna Therapeutics Inc. (2) · University of Nottingham (2) · AbbVie (1) · Aimmune Nestlé Health Science US R&D, LLC (1) · Amgen (1)
United States (35) · United Kingdom (13) · Turkey (Türkiye) (6) · Spain (5) · Belgium (4) · France (4) · Italy (4) · Australia (3) · Canada (3) · Egypt (3) · Poland (3) · Germany (2) · Hungary (2) · Netherlands (2) · Pakistan (2)
Kristin Riekert, PhD (2) · Alexander Mischnik, Prof. Dr. med. (1) · Alexandru Crisan, Phd (1) · Amanda Bruce, PhD (1) · Andres Floto (1) · Bettina Mittendorfer, PhD (1) · Brandon Zanette, PhD (1) · Chris Landon, M.D. (1) · Danish Hassan, PhD (1) · Ece Ocak, Dr (1)
PMID 11562511, PMID 12186831, PMID 1435933, PMID 14681839, PMID 18026621, PMID 19464863, PMID 21471106, PMID 26604327, PMID 26707538, PMID 27189798, PMID 27259460, PMID 27836958, PMID 28441934, PMID 28978987, PMID 29162121, PMID 29506920, PMID 30050169, PMID 30234080, PMID 30623052, PMID 30956204, PMID 31613151, PMID 31741352, PMID 32660459, PMID 38626948, PMID 38678203, PMID 38989817, PMID 39785198, PMID 41324124, PMID 41793435, PMID 42379640, PMID 42772816, PMID 8499054, PMID 8630582
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