4 completed, 3 recruiting, 2 terminated, 1 not yet recruiting. 10 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 10 | Completed 4, Recruiting 3, Terminated 2, Not yet recruiting 1 |
Follow Cystic Fibrosis (CF): new trials by email Literature Review of Cystic Fibrosis (CF) trials Research Report on Cystic Fibrosis (CF)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Evaluate Safety and Explore Efficacy of New Lipase NHS7108 in Adult Participants With Exocrine Pancreatic Insufficiency. NHS7108, Zenpep® - Exocrine Pancreatic Insufficiency (EPI), Cystic Fibrosis (CF) | Phase 2 | Recruiting | Aimmune Nestlé Health Science US R&D, LLC | 66 | 2026-10-01 | 2026-10-01 |
| Verapamil Effect in Cystic Fibrosis-related Dysglycemia Verapamil Hydrochloride - Cystic Fibrosis Related Diabetes, Cystic Fibrosis (CF) | Phase 2 | Not yet recruiting | Rhode Island Hospital | 30 | 2026-08-01 | 2026-07-09 |
| Phase 2 Study to Assess the Safety and Efficacy of ANG003 ANG003 Dose A, ANG003 Dose B, Creon - Exocrine Pancreatic Insufficiency (EPI), Cystic Fibrosis (CF) | Phase 2 | Recruiting | Anagram Therapeutics, Inc. | 113 | 2026-04-24 | 2026-10-30 |
| Proof-of-concept Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of SION-719 When Added to Trikafta SION-719, Placebo-to-match SION-719 - Cystic Fibrosis (CF) | Phase 2 | Completed | Sionna Therapeutics Inc. | 15 | 2025-11-03 | 2026-09-10 |
| Study With Phage for CF Subjects With Pseudomonas Lung Infection BX004, Placebo - Chronic Pseudomonas Aeruginosa Infection, Cystic Fibrosis (CF) | Phase 2 | Recruiting | BiomX Ltd | 63 | 2025-07-02 | 2025-07-22 |
| Study to Evaluate Adverse Events and Change in Disease Activity With Oral Capsules of Galicaftor/Navocaftor/ABBV-119 or Galicaftor/Navocaftor/ABBV-576 Combination Therapies in Adult Participants With Cystic Fibrosis ABBV-576, Galicaftor, Placebo - Cystic Fibrosis (CF) | Phase 2 | Terminated | AbbVie | 48 | 2021-09-20 | 2024-07-16 |
| OPTION 2: A Trial to Assess the Safety and Efficacy of MS1819 in Enteric Capsules in Patients With Cystic Fibrosis MS1819, Porcine PERT - Exocrine Pancreatic Insufficiency (EPI), Cystic Fibrosis (CF) | Phase 2 | Completed | Entero Therapeutics | 27 | 2020-07-20 | 2022-09-13 |
| Trial of Inhaled Molgramostim in Cystic Fibrosis Subjects With Nontuberculous Mycobacterial Infection Molgramostim nebulizer solution, PARI eFlow nebulizer system - Mycobacterium Infections, Nontuberculous, Cystic Fibrosis (CF) | Phase 2 | Terminated | Savara Inc. | 14 | 2019-06-20 | 2023-01-10 |
| OPTION: A Trial to Assess the Safety & Efficacy of MS1819 in Patients With Exocrine Pancreatic Insufficiency Due to Cystic Fibrosis MS1819, Porcine PERT - Exocrine Pancreatic Insufficiency (EPI), Cystic Fibrosis (CF) | Phase 2 | Completed | Entero Therapeutics | 41 | 2019-01-10 | 2022-06-06 |
| Safety, Tolerability and Efficacy of MP-376 Given for 28 Days to Cystic Fibrosis (CF) Patients MP-376, Placebo - Cystic Fibrosis (CF) | Phase 2 | Completed | Amgen | 151 | 2008-06-01 | 2024-12-27 |
Cystic Fibrosis (10) · Exocrine Pancreatic Insufficiency (4) · Mycobacterium Infections, Nontuberculous (1) · Pancreatic Diseases (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (10) · Digestive System Diseases (10) · Genetic Diseases, Inborn (10) · Infant, Newborn, Diseases (10) · Lung Diseases (10) · Respiratory Tract Diseases (10) · Pancreatic Diseases (9) · Actinomycetales Infections (1) · Bacterial Infections (1) · Bacterial Infections and Mycoses (1) · Gram-Positive Bacterial Infections (1) · Infections (1) · Mycobacterium Infections (1)
Pancrelipase (2) · GLPG2222 (1) · Verapamil (1) · regramostim (1)
Entero Therapeutics (2) · AbbVie (1) · Aimmune Nestlé Health Science US R&D, LLC (1) · Amgen (1) · Anagram Therapeutics, Inc. (1) · BiomX Ltd (1) · Rhode Island Hospital (1) · Savara Inc. (1) · Sionna Therapeutics Inc. (1)
United States (10) · Poland (3) · Australia (2) · Hungary (2) · Netherlands (2) · Belgium (1) · Bulgaria (1) · Germany (1) · Italy (1) · New Zealand (1) · Slovakia (1) · Spain (1) · United Kingdom (1)
Jerry Nick, MD (1) · Monique Bunyan (1) · Urania Rappo, MD (1)
2008 (1), 2025 (1)