11 completed, 5 unknown, 4 not yet recruiting, 3 recruiting. 21 Not applicable, 1 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 21 | Completed 10, Not yet recruiting 4, Unknown 4, Recruiting 3 |
| Phase 3 | 1 | Active not recruiting 1 |
| Phase 4 | 1 | Completed 1 |
Follow Cryotherapy: new trials by email Literature Review of Cryotherapy trials Research Report on Cryotherapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cryotherapy, PGE2, NGF Levels and Pain After Endodontic Retreatment Intracanal cryotherapy, Room-temperature saline irrigation - Asymptomatic Apical Periodontitis, Endodontic Retreatment | Not applicable | Not yet recruiting | Alanya Alaaddin Keykubat University | 100 | 2026-08-01 | 2026-07-29 |
| Effect of Two Different Cryotherapy Irrigation Protocols on Postoperative Endodontic Pain Full Cryotherapy Irrigation (FC), Final Flush Cryotherapy Irrigation (FFC), Conventional Irrigation (CI) - Cryotherapy | Not applicable | Not yet recruiting | Cairo University | 45 | 2026-06-15 | 2026-06-30 |
| Effect of Intracanal Cryotherapy on Postoperative Endodontic Pain root canal treatment and cryotherapy - Periapical Periodontitis, Asymptomatic Irreversible Pulpitis | Not applicable | Completed | Recep Tayyip Erdogan University | 132 | 2026-05-11 | 2026-07-17 |
| Post-Market Registry of Transbronchial Cryo-assisted RFA During Routine Standard Bronchoscopic Tumor Stagng and Resection Cryotherapy - NSCLC, Cryotherapy | Not applicable | Not yet recruiting | Elisabethinen Hospital | 20 | 2026-05-01 | 2026-04-15 |
| Effect of Cryotherapy on Anesthetic Success and Pain in Irreversible Pulpitis infiltration anesthesia alone, mandibular anesthesia alone, infiltration anesthesia combined with cryotherapy - Irreversible Pulpitis, Cryotherapy | Not applicable | Not yet recruiting | TC Erciyes University | 100 | 2026-01-30 | 2026-02-11 |
| Acute Cryotherapy on Musculoskeletal Function and Biomarkers Cryotherapy, Eccentric exercise-induced muscle damage - Exercise Induced Muscle Damage, Cryotherapy | Not applicable | Recruiting | University of Texas, El Paso | 60 | 2025-11-15 | 2026-10-22 |
| Monocentric Randomised Controlled Trial Assessing Cryocompression Following Total Knee Replacement Cryotherapy, Game Ready - Total Knee Anthroplasty, Cryotherapy | Not applicable | Recruiting | Clinique des Cèdres | 138 | 2025-10-27 | 2026-01-26 |
| Cryotherapy as a Topical Anesthetic in Healthy Children Cryotherapy, topical anesthetic, Topical anesthetic gel - Healthy, Topical Anesthesia | Phase 4 | Completed | Ondokuz Mayıs University | 100 | 2025-09-01 | 2026-02-09 |
| 64Cu-SAR-bisPSMA Positron Emission Tomography: A Phase 3 Study of Participants With Biochemical Recurrence of Prostate Cancer 64Cu-SAR-bisPSMA - Prostate Cancer, Prostate Cancer Patients With Detectable PSA Following Prostatectomy | Phase 3 | Active not recruiting | Clarity Pharmaceuticals Ltd | 220 | 2025-05-16 | 2026-05-14 |
| Cryotherapy on Muscle Function Cold pack application, Cold spray application - Cold, Cryotherapy | Not applicable | Completed | Okan University | 52 | 2025-05-15 | 2025-06-06 |
| Intracoronary Cryotherapy Effect on Stabilization of Vulnerable Plaque in Patients With Stable Angina or ACS - A Traditional Feasibility Study Intracoronary Cryotherapy - Coronary Arterial Disease (CAD), Plaque | Not applicable | Recruiting | Cryotherapeutics SA | 30 | 2025-03-01 | 2026-04-06 |
| Prolonged Cryocompression and Skin Temperature: a Safety and Feasibility Pilot Prolonged (2-hour) cryocompression therapy - Skin Temperature Change, Adverse Effects | Not applicable | Completed | University of Winchester | 16 | 2025-02-12 | 2025-06-19 |
| Focal Cryoballoon Ablation for Malignant Dysphagia Cryotherapy - Dysphagia, Esophageal Cancer | Not applicable | Unknown | Laura Boer | 20 | 2024-06-24 | 2024-10-01 |
| Effect of Preoperative Cold Therapy on Early Postoperative Outcomes in Total Knee Arthroplasty Preoperative and Postoperative Cold Therapy with Gel Cold Pack, Postoperative Cold Therapy with Gel Cold Pack - Knee Osteoarthritis, Total Knee Arthroplasty | Not applicable | Completed | Ankara City Hospital Bilkent | 208 | 2024-06-10 | 2025-08-21 |
| Effect of Intracanal Cryotherapy on Postoperative Pain Cryotherapy, Control - Retreatment, Cryotherapy | Not applicable | Completed | Kutahya Health Sciences University | 60 | 2024-01-03 | 2025-03-04 |
| Is Cryotherapy Effective as a Therapeutic Option for Oral Lesion Cryotherapy - Cryotherapy, Oral Lesions | Not applicable | Completed | October 6 University | 15 | 2023-02-01 | 2024-01-09 |
| Effect of Cryotherapy on Post-endodontic Pain Cryotherapy, Occlusal reduction - Cryotherapy | Not applicable | Completed | Gulf Medical University | 60 | 2022-09-12 | 2026-10-06 |
| SCAP vs HIFU for Recurrent Prostate Cancer After Radiation Therapy Local treatment of the prostate (SCAP or HIFU) - Cryotherapy, High Intensity Focused Ultrasounds | Unknown | University Hospital Virgen de las Nieves | 50 | 2021-10-01 | 2021-09-16 | |
| Pain During Femoral Sheath Removal in Patients Undergoing Percutaneous Coronary Intervenion Virtual Reality Glasses, Ice Application Group, Control Group - Percutaneous Coronary Intervention, Virtual Reality | Not applicable | Completed | Amasya University | 108 | 2021-07-12 | 2024-06-06 |
| Salvage Cryotherapy for Recurrent Prostate Cancer After Radiation Therapy Salvage cryoablation of the prostate (SCAP) - Prostate Cancer, Cryotherapy | Not applicable | Unknown | Ignacio Puche Sanz | 100 | 2021-05-01 | 2021-05-18 |
Showing 20 of 24. Sign in to see all of them.
Prostatic Neoplasms (3) · Pain (2) · Pain, Postoperative (2) · Agnosia (1) · Common Cold (1) · Deglutition Disorders (1) · Esophageal Neoplasms (1) · Hereditary Sensory and Autonomic Neuropathies (1) · Insulin Resistance (1) · Osteoarthritis, Knee (1) · Overweight (1) · Patient Satisfaction (1) · Periapical Periodontitis (1) · Plaque, Amyloid (1)
Pathological Conditions, Signs and Symptoms (7) · Signs and Symptoms (6) · Neurologic Manifestations (5) · Neoplasms (4) · Neoplasms by Site (4) · Genital Diseases (3) · Genital Diseases, Male (3) · Genital Neoplasms, Male (3) · Male Urogenital Diseases (3) · Prostatic Diseases (3) · Urogenital Diseases (3) · Urogenital Neoplasms (3) · Nervous System Diseases (2) · Pain (2) · Pathologic Processes (2)
Cryotherapy (11) · Control Groups (2) · Anesthesia, Local (1) · Anesthetics, Local (1) · Low-Level Light Therapy (1) · SREBP cleavage-activating protein (1)
Cairo University (2) · Alanya Alaaddin Keykubat University (1) · Amasya University (1) · Ankara City Hospital Bilkent (1) · Clarity Pharmaceuticals Ltd (1) · Clinique des Cèdres (1) · Cryotherapeutics SA (1) · Elisabethinen Hospital (1) · Gdansk University of Physical Education and Sport (1) · Gulf Medical University (1) · Ignacio Puche Sanz (1) · Kutahya Health Sciences University (1) · Laura Boer (1) · Misr International University (1) · October 6 University (1)
Turkey (Türkiye) (8) · Egypt (2) · France (2) · Spain (2) · United Kingdom (2) · United States (2) · Australia (1) · Austria (1) · Belgium (1) · Netherlands (1) · Poland (1) · United Arab Emirates (1)
Ayman G Matar, PhD (1) · Carlos Collet, MD (1) · Christopher Lambers (1) · Enrique Gomez-Gomez, MD (1) · Ewa Ziemann, Professor (1) · Ghada M Elhafez, Prof. (1) · Ignacio Puche-Sanz, MD, PhD (1) · Naglaa M Elhafez, Prof. (1)
PMID 15297952, PMID 25059851, PMID 39773549, PMID 40601965, PMID 9145556, PMID 9486722