17 completed, 8 recruiting, 4 not yet recruiting, 4 terminated. 7 Phase 2, 6 Not applicable, 4 Phase 1, 3 Phase 3, 3 Phase 4.
Follow Crohns Disease: new trials by email Literature Review of Crohns Disease trials Research Report on Crohns Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Oral N-acetylglucosamine in Crohn's Disease N-Acetylglucosamine (GlcNAc) - Crohns Disease | Phase 2 | Not yet recruiting | Johns Hopkins University | 40 | 2026-11-01 | 2026-09-11 |
| Virtual Versus Dye-based Chromoendoscopy in Inflammatory Bowel Disease Surveillance Colonoscopy Virtual Chromoendoscopy, Dye-Based Chromoendoscopy - Inflammatory Bowel Disease (IBD), Ulcerative Colitis (Disorder) | Not applicable | Not yet recruiting | Region Stockholm | 480 | 2026-05-01 | 2026-03-20 |
| Prospective Evaluation of the Carbon Footprint and Clinical Utility of IBUS Compared to Colonoscopy and Enterography in UC and CD Ulcerative Colitis (UC), Crohns Disease | Recruiting | Asian Institute of Gastroenterology, India | 200 | 2026-03-01 | 2026-05-12 | |
| OPTImization of Inflammatory Bowel Disease Treatment Through Understanding of Gut VIRome Heterogeneity IBD (Inflammatory Bowel Disease), Crohns Disease | Not yet recruiting | Andreas Munk Petersen | 40 | 2025-12-01 | 2025-11-20 | |
| Magnesium in Gastrointestinal Disease Colitis Ulcerosa, Colitis Ulcerative | Recruiting | University of Aarhus | 120 | 2025-11-03 | 2026-01-14 | |
| Protease Regulation and Impact of Sodium as Mechanisms of Inflammation in IBD Crohns Disease | Recruiting | McMaster University | 300 | 2025-08-18 | 2026-07-30 | |
| Evaluating the Efficacy and Safety of Mirikizumab in Adults Over 60 With Moderate to Severe Crohn's Disease and Ulcerative Colitis Mirikizumab - Crohn Disease (CD), Crohns Disease | Phase 4 | Not yet recruiting | Rubix LS | 150 | 2025-07-16 | 2025-07-10 |
| Treatment of Moderate to Severe Refractory Crohn's Disease TRX103, Cyclophosphamide - Crohns Disease | Phase 1 / Phase 2 | Recruiting | Tr1X, Inc. | 39 | 2025-05-05 | 2025-12-10 |
| A Study to Evaluate the Effect of Fecal Transplant and Dietary Changes on Disease Activity in Patients With Crohn Disease on Advanced Therapies Fecal Microbial Transplantation, Crohns Disease Exclusion Diet, Sham transplantation - Crohns Disease | Not applicable | Recruiting | All India Institute of Medical Sciences | 168 | 2025-03-15 | 2025-04-04 |
| A Long-term Extension (LTE) Study of Guselkumab in Pediatric Participants Guselkumab - Crohns Disease, Colitis, Ulcerative | Phase 3 | Recruiting | Janssen Research & Development, LLC | 196 | 2024-10-29 | 2026-09-25 |
| Development of a Novel Endoscopic Index and Patient-reported Outcome Measure for Clinical Trials in Participants With Permanent Ileostomy Crohns Disease | Recruiting | Alimentiv Inc. | 50 | 2024-06-19 | 2025-11-12 | |
| Development and Validation of a New Paediatric Inflammatory Bowel Disease NUTrition Risk Score (PIBD-NUTS) Malnutriton Screening Tool (PYMS) - Inflammatory Bowel Diseases (IBD), Crohns Disease | Active not recruiting | University of Glasgow | 2000 | 2024-06-15 | 2026-08-11 | |
| Pregnant Women With and Without Crohns Disease to Explore the Role of Plastics and Toxins in Intestinal Inflammation Crohns Disease, Pregnancy | Recruiting | Icahn School of Medicine at Mount Sinai | 46 | 2023-08-15 | 2026-01-07 | |
| Afimkibart (RO7790121) for the Treatment of Moderate to Severe Active Crohn's Disease Afimkibart - Crohns Disease | Phase 2 | Active not recruiting | Hoffmann-La Roche | 21 | 2023-07-24 | 2026-09-16 |
| AZD7798 Safety, Tolerability, and Pharmacokinetics After a Single Ascending and Repeat Dose Administrations to Healthy Subjects, and Patients With Crohn's Disease AZD7798, Placebo - Healthy Subjects, Crohns Disease | Phase 1 | Completed | AstraZeneca | 112 | 2022-07-12 | 2025-12-03 |
| A Study on Administration Choices of Vedolizumab and Outcomes for Adults With Inflammatory Bowel Disease (IBD) (VARIETY - CROATIA AND SLOVENIA) Inflammatory Bowel Diseases, Crohns Disease | Completed | Takeda | 120 | 2022-02-22 | 2024-04-16 | |
| A Study on How Vedolizumab is Given and the Outcomes for Adults With Inflammatory Bowel Disease (VARIETY-Belgium) Inflammatory Bowel Diseases, Colitis, Ulcerative | Completed | Takeda | 185 | 2021-12-02 | 2024-08-06 | |
| A Study in Adults With Ulcerative Colitis (UC) or Crohn's Disease (CD) Receiving Vedolizumab in Real-World Practice in Switzerland Inflammatory Bowel Diseases, Crohns Disease | Completed | Takeda | 92 | 2021-09-08 | 2025-12-29 | |
| A Study of Vedolizumab in Adults With Ulcerative Colitis (UC) or Crohn's Disease (CD) in Real-World Practice Inflammatory Bowel Diseases, Crohns Disease | Completed | Takeda | 99 | 2021-08-18 | 2024-10-16 | |
| A Study of Surgical Interventions in Fistulizing Conditions Crohns Disease, Fistula | Completed | Takeda | 646 | 2021-08-05 | 2026-05-01 |
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Crohn Disease (40) · Colitis, Ulcerative (15) · Inflammatory Bowel Diseases (10) · Fistula (3) · Abdominal Pain (1) · Abscess (1) · Arthritis, Juvenile (1) · Arthritis, Psoriatic (1) · Colitis (1) · Colorectal Neoplasms (1) · Diarrhea (1) · Irritable Bowel Syndrome (1) · Magnesium Deficiency (1) · Rectovaginal Fistula (1) · Vitamin D Deficiency (1)
Digestive System Diseases (40) · Gastroenteritis (40) · Gastrointestinal Diseases (40) · Intestinal Diseases (40) · Inflammatory Bowel Diseases (30) · Colonic Diseases (15) · Colitis (14) · Pathological Conditions, Signs and Symptoms (4) · Pathological Conditions, Anatomical (3) · Deficiency Diseases (2) · Malnutrition (2) · Nutrition Disorders (2) · Nutritional and Metabolic Diseases (2) · Rectal Diseases (2) · Signs and Symptoms (2)
guselkumab (2) · 13-valent pneumococcal vaccine (1) · Acetylglucosamine (1) · Atorvastatin (1) · Certolizumab Pegol (1) · Colesevelam Hydrochloride (1) · Cyclophosphamide (1) · Glatiramer Acetate (1) · Mercaptopurine (1) · Pneumococcal Vaccines (1) · Restraint, Physical (1) · Vitamin D (1) · mirikizumab (1)
Takeda (6) · University of Aarhus (2) · Alimentiv Inc. (1) · All India Institute of Medical Sciences (1) · Andreas Munk Petersen (1) · Asian Institute of Gastroenterology, India (1) · AstraZeneca (1) · Baylor College of Medicine (1) · Cedars-Sinai Medical Center (1) · Celularity Incorporated (1) · Florian Beigel (1) · GlaxoSmithKline (1) · Hoffmann-La Roche (1) · Icahn School of Medicine at Mount Sinai (1) · Janssen Pharmaceutical K.K. (1)
United States (15) · Germany (5) · Belgium (4) · Canada (4) · Denmark (4) · United Kingdom (4) · Austria (3) · France (3) · Israel (3) · Netherlands (3) · Poland (3) · China (2) · Croatia (2) · India (2) · Italy (2)
Anders Bredberg, MD, PhD (1) · Andreas M Petersen, MD (1) · Bincy P. Abraham, MD, MS (1) · Dana S Hardin, MD (1) · David A Schwartz, MD (1) · David Armstrong, MD (1) · Florian Beigel, M.D. (1) · Florian Rieder (1) · GIl Y Melmed, MD, MS (1) · Gerhard Jahreis, Prof. Dr. (1) · Gunnel Bredberg, MD, PhD (1) · Gustav Dobos, Prof, MD (1)
PMID 19421322, PMID 24953836, PMID 26275480, PMID 31290715, PMID 32681898, PMID 33264183, PMID 34853058, PMID 35550801
2023 (2), 2005 (1), 2009 (1), 2025 (1), R01DK141870 (1)