3 completed, 1 recruiting. 4 Phase 1, 1 Phase 2.
By phase and status
Follow Crohns Disease: new trials by email Literature Review of Crohns Disease trials Research Report on Crohns Disease
Trials (filtered) newest first · largest first
All 4 trials
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|
Treatment of Moderate to Severe Refractory Crohn's Disease
TRX103, Cyclophosphamide - Crohns Disease | Phase 1 / Phase 2 | Recruiting | 39 | 2025-05-05 | 2025-12-10 |
AZD7798 Safety, Tolerability, and Pharmacokinetics After a Single Ascending and Repeat Dose Administrations to Healthy Subjects, and Patients With Crohn's Disease
AZD7798, Placebo - Healthy Subjects, Crohns Disease | Phase 1 | Completed | 112 | 2022-07-12 | 2025-12-03 |
A Randomized, Double-Blind, Placebo-Controlled Dose-Escalation Study to Determine the Safety and Efficacy of Intravenous Infusion of Human Placenta-Derived Cells (PDA001) for the Treatment of Crohn's Disease
PDA001, Vehicle Controlled Placebo - Crohns Disease | Phase 1 | Completed | 14 | 2013-03-01 | 2018-03-01 |
Pilot Comparative Bioavailability Study of 6Mercaptopurine (Delayed Release vs. Purinethol) in Crohns Disease Patients
Delayed Release 6 mercaptopurine, 6 Mercaptopurine - Crohns Disease | Phase 1 | Completed | 12 | 2008-12-01 | 2009-07-17 |
Narrower conditions
Crohn Disease (4) · Abdominal Pain (1) · Diarrhea (1) · Fistula (1)
Broader conditions
Digestive System Diseases (4) · Gastroenteritis (4) · Gastrointestinal Diseases (4) · Inflammatory Bowel Diseases (4) · Intestinal Diseases (4) · Pathological Conditions, Signs and Symptoms (2) · Signs and Symptoms (2) · Signs and Symptoms, Digestive (2) · Neurologic Manifestations (1) · Pain (1) · Pathological Conditions, Anatomical (1)
Interventions
Cyclophosphamide (1) · Mercaptopurine (1)
Sponsors
AstraZeneca (1) · Celularity Incorporated (1) · Teva GTC (1) · Tr1X, Inc. (1)
Countries
United States (2) · Israel (1) · United Kingdom (1)
Top investigators
Monica E Luchi, MD (1) · Yaron Ilan, MD (1)