12 completed, 1 recruiting, 1 unknown, 1 withdrawn. 15 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 15 | Completed 12, Recruiting 1, Unknown 1, Withdrawn 1 |
| Phase 2 | 4 | Completed 2, Recruiting 1, Withdrawn 1 |
Follow Coronary Heart Disease: new trials by email Literature Review of Coronary Heart Disease trials Research Report on Coronary Heart Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study on Yiyang Huoluo Decoction in the Treatment of Coronary Heart Disease Yiyang Huoluo Decoction, conventional western medicine treatment - Coronary Heart Disease, Coronary Artery Disease | Phase 1 / Phase 2 | Recruiting | Xia Liang | 30 | 2026-01-16 | 2026-03-25 |
| A Study of Atorvo+™ in Healthy Adult Participants Atorvo+™ (Arm1), Atorvo+™ +CBD (Arm 2), Atorvo+™ +CBD (Arm 3) - Coronary Heart Disease, Dyslipidemias | Phase 1 | Completed | Indication Bioscience LLC | 24 | 2025-01-28 | 2025-12-19 |
| the Accuracy and Safety of Coronary Artery Contrast-enhanced Magnetic Resonance Imaging With Polysaccharide Superparamagnetic Iron Oxide Nanoparticle domestic polysaccharide superparamagnetic iron oxide nanoparticle - Coronary Heart Disease | Phase 1 | Completed | The First Affiliated Hospital with Nanjing Medical University | 30 | 2021-10-13 | 2023-01-13 |
| Alirocumab and Reverse Cholesterol Transport Alirocumab, Placebos - Atherosclerosis, Coronary Heart Disease | Phase 1 | Completed | Washington University School of Medicine | 28 | 2017-06-01 | 2018-11-07 |
| Physiological Study of Human Cholesterol Metabolism and Excretion Ezetimibe - Coronary Heart Disease, Cardiovascular Disease | Phase 1 | Completed | Richard E. Ostlund Jr., MD | 132 | 2014-01-01 | 2016-05-06 |
| Effect of Remote Ischemic Preconditioning in Patient Undergoing Cardiac Bypass Surgery Remote ischemic preconditioning, Placebo - Coronary Heart Disease | Phase 1 | Completed | University College London Hospitals | 200 | 2010-12-01 | 2023-11-29 |
| Anfibatide Phase 1 Clinical Trial in Healthy Volunteers Anfibatide - Coronary Heart Disease, Coagulation Disorder | Phase 1 | Completed | Lee's Pharmaceutical Limited | 94 | 2010-09-01 | 2012-04-30 |
| Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of APL180 APL180, Placebo - Coronary Heart Disease | Phase 1 | Completed | Novartis Pharmaceuticals | 104 | 2009-06-01 | 2009-11-20 |
| Effect of CYP3A Genetic Polymorphisms on the Pharmacokinetics of Atorvastatin Atorvastatin - Coronary Heart Disease | Phase 1 | Completed | Liuhuaqiao Hospital | 20 | 2009-06-01 | 2011-11-29 |
| Immunoadsorption and Immunoglobulin Substitution for Heart Failure After Myocardial Infarction Immunoadsorption / Immunoglobulin substitution - Heart Failure, Coronary Heart Disease | Phase 1 / Phase 2 | Withdrawn | University Medicine Greifswald | 2008-09-01 | 2016-05-11 | |
| A Study to Assess the Safety, Tolerability, and Effects of MK-0974 (Telcagepant) on Exercise Tolerance in Patients With Stable Angina (MK-0974-014) telcagepant, Placebo to telcagepant - Angina Pectoris, Coronary Heart Disease | Phase 1 | Completed | Merck Sharp & Dohme LLC | 64 | 2008-02-12 | 2018-10-18 |
| Safety and Efficacy of APL180 in Healthy Volunteers and Patients With Coronary Heart Disease (CHD) APL180, Placebo - Coronary Heart Disease | Phase 1 / Phase 2 | Completed | Novartis | 176 | 2007-11-01 | 2020-12-24 |
| Stem Cell Therapy for Vasculogenesis in Patients With Severe Myocardial Ischemia stem cell - Myocardial Ischemia, Coronary Heart Disease | Phase 1 / Phase 2 | Completed | Copenhagen University Hospital, Rigshospitalet | 31 | 2005-12-01 | 2013-05-31 |
| Evaluating Tools for Health Promotion and Disease Prevention Familial risk assessment and personalized prevention messages - Coronary Heart Disease, Stroke | Phase 1 | Completed | Centers for Disease Control and Prevention | 8400 | 2005-09-01 | 2010-01-07 |
| A Prospective Evaluation in a Randomized Trial of TAXUS in the Treatment of De Novo Coronary Artey Lesions TAXUS Element Stent or TAXUS Express Stent - Coronary Heart Disease | Phase 1 | Unknown | National University Hospital, Singapore | 2008-06-09 |
Coronary Disease (15) · Atherosclerosis (3) · Coronary Artery Disease (2) · Dyslipidemias (2) · Angina Pectoris (1) · Arachnodactyly (1) · Breast Neoplasms (1) · Cardiovascular Diseases (1) · Colorectal Neoplasms (1) · Diabetes Mellitus (1) · Heart Failure (1) · Hemostatic Disorders (1) · Inflammation (1) · Myocardial Ischemia (1) · Ovarian Neoplasms (1)
Heart Diseases (15) · Vascular Diseases (15) · Cardiovascular Diseases (14) · Myocardial Ischemia (14) · Arterial Occlusive Diseases (4) · Arteriosclerosis (4) · Metabolic Diseases (3) · Nutritional and Metabolic Diseases (3) · Lipid Metabolism Disorders (2) · Pathological Conditions, Signs and Symptoms (2) · Adnexal Diseases (1) · Brain Diseases (1) · Breast Diseases (1) · Central Nervous System Diseases (1) · Cerebrovascular Disorders (1)
26S proteasome non-ATPase regulatory subunit 13 (1) · Atorvastatin (1) · Ezetimibe (1) · agkisacucetin protein, Agkistrodon acutus (1) · alirocumab (1) · telcagepant (1)
Centers for Disease Control and Prevention (1) · Copenhagen University Hospital, Rigshospitalet (1) · Indication Bioscience LLC (1) · Lee's Pharmaceutical Limited (1) · Liuhuaqiao Hospital (1) · Merck Sharp & Dohme LLC (1) · National University Hospital, Singapore (1) · Novartis (1) · Novartis Pharmaceuticals (1) · Richard E. Ostlund Jr., MD (1) · The First Affiliated Hospital with Nanjing Medical University (1) · University College London Hospitals (1) · University Medicine Greifswald (1) · Washington University School of Medicine (1) · Xia Liang (1)
United States (5) · China (3) · Denmark (3) · Germany (2) · Israel (2) · Netherlands (2) · United Kingdom (2) · Australia (1) · Belgium (1) · South Africa (1)
Richard E Ostlund, MD (2) · Astrid Hummel, MD (1) · Chunjian Li, Dr, PhD (1) · Daniel Beug, MD (1) · Derek M Yellon, PhD DSc (1) · James E Smeeding (1) · Jens Kastrup, MD DMSc (1) · Lars R Herda, MD (1) · Louise S Acheson, MD, MS (1) · Mack T Ruffin IV, MD, MPH (1) · Marcus Doerr, MD (1) · Stephan B Felix, MD (1)
PMID 17707752, PMID 19460658, PMID 19508973, PMID 21900440, PMID 22257420, PMID 22278333, PMID 22992357, PMID 24211066, PMID 24214373, PMID 25252696, PMID 25901453, PMID 28279967, PMID 28982667, PMID 34083615, PMID 37341530, PMID 37463240, PMID 42854505
R01HL108160 (1)