4 completed, 2 enrolling by invitation, 2 not yet recruiting, 1 unknown. 4 Not applicable, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 4 | Enrolling by invitation 2, Not yet recruiting 1, Unknown 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
Follow Comatose: new trials by email Literature Review of Comatose trials Research Report on Comatose
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Kinetics and Prognostic Value of NeuroFilament Light in Post-cardiac Arrest: A Prospective Multicenter Study Value of neurofilament light chain (NFL) at different time points - Cardiac Arrest (CA), Intensive Care Unit (ICU) Admission | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 270 | 2026-09-01 | 2026-08-12 | |
| NEURO - Prognostication Using Late Somatosensory Evoked - Potentials EEGs - Comatose, Prognosis | Not applicable | Not yet recruiting | University Hospital, Bordeaux | 50 | 2026-06-30 | 2026-04-02 |
| A Study of Transcutaneous Electrical Stimulation As a Noxious Stimulus for the Glasgow Coma Scale Transcutaneous electrical stimulation, Standard of Care (SOC) - Comatose | Not applicable | Enrolling by invitation | Markey Olson | 90 | 2024-10-31 | 2024-11-08 |
| Prognostication of Recovery in Early Disorders of Consciousness Study Functional MRI (fMRI) - Disorder of Consciousness, Comatose | Not applicable | Enrolling by invitation | University of Pennsylvania | 150 | 2023-03-08 | 2026-07-30 |
| Non-invasive Airway Management of Comatose Poisoned Emergency Patients Close monitoring, Endotracheal intubation - Poisoning, Consciousness, Level Altered | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 237 | 2021-05-16 | 2023-07-17 |
| EXPRE-SON-REA : Expressive Own Names in Neurophysiologic Assessment of Comatose Patients Evoked related potential - P3 paradigm - Comatose, Neurophysiologic Abnormality | Not applicable | Unknown | Centre Hospitalier St Anne | 78 | 2020-07-30 | 2021-03-17 |
| Automated Pupillometry for Coma Prognostication After Cardiac Arrest Cardiac Arrest, Comatose | Completed | Centre Hospitalier Universitaire Vaudois | 470 | 2015-01-01 | 2021-09-16 | |
| Ticagrelor for the Comatose Comatose | Completed | Lene Holmvang | 47 | 2014-09-01 | 2016-04-07 | |
| Pilot Clinical Study of the LRS ThermoSuit™ System in Post Arrest Patients ThermoSuit(R) System - Cardiac Arrest, Comatose | Phase 1 | Completed | Life Recovery Systems | 10 | 2006-10-01 | 2008-01-04 |
Coma (9) · Heart Arrest (3) · Consciousness Disorders (2) · Charcot-Marie-Tooth disease, Type 1F (1) · Hypothermia (1) · Persistent Vegetative State (1) · Poisoning (1)
Nervous System Diseases (9) · Neurobehavioral Manifestations (9) · Neurologic Manifestations (9) · Pathological Conditions, Signs and Symptoms (9) · Signs and Symptoms (9) · Unconsciousness (9) · Consciousness Disorders (7) · Cardiovascular Diseases (3) · Heart Diseases (3) · Mental Disorders (2) · Neurocognitive Disorders (2) · Body Temperature Changes (1) · Brain Damage, Chronic (1) · Brain Diseases (1) · Central Nervous System Diseases (1)
Drug Delivery Systems (1) · Intubation, Intratracheal (1) · Magnetic Resonance Imaging (1) · Standard of Care (1) · Transcutaneous Electric Nerve Stimulation (1)
Assistance Publique - Hôpitaux de Paris (2) · Centre Hospitalier St Anne (1) · Centre Hospitalier Universitaire Vaudois (1) · Lene Holmvang (1) · Life Recovery Systems (1) · Markey Olson (1) · University Hospital, Bordeaux (1) · University of Pennsylvania (1)
France (5) · United States (2) · Austria (1) · Belgium (1) · Denmark (1) · Germany (1) · Italy (1) · Luxembourg (1) · Netherlands (1) · Sweden (1) · Switzerland (1)
Brandon M Fox, MD, PhD (1) · David J Fischer, MD (1) · Lene Holmvang, MD, PHD (1) · Mauro Oddo, MD (1) · Michael Holzer, MD (1) · Sarah Benghanem (1)
K23NS136745 (1)