33 completed, 26 unknown, 15 recruiting, 4 terminated. 48 Not applicable, 2 Phase 2, 2 Phase 3, 2 Phase 4, 1 Phase 1.
Follow Cleft Lip and Palate: new trials by email Literature Review of Cleft Lip and Palate trials Research Report on Cleft Lip and Palate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cleft Lip and Palate Treatment Outcomes Study Cleft Lip and Palate | Not yet recruiting | University of Florida | 100 | 2026-11-01 | 2026-11-13 | |
| Analgosedation With Ketamine, Nalbuphine, or Dexmedetomidine for Suture Removal in Children After Cleft Surgery ketamine, Nalbuphine, Dexmedetomidine - Orofacial Clefts, Cleft Lip and Palate | Not applicable | Recruiting | University Medical Centre Ljubljana | 60 | 2025-09-01 | 2026-01-14 |
| High and Low Intensity Speech Intervention in Children With a Cleft Palate: Perceptions of Children, Their Caregivers and Speech-language Pathologists High intensive combined phonetic-phonological intervention, Low intensive combined phonetic-phonological intervention - Cleft Lip and Palate, Speech Disorders in Children | Recruiting | University Ghent | 175 | 2025-05-01 | 2025-03-26 | |
| Evaluation of Maxillary Expansion Using Clear Aligners' Therapy in Patients With Cleft Lip and Palate at the Mixed Dentition Stage clear aligners - Maxillary Deficiency, Cleft Lip and Palate | Not applicable | Recruiting | Cairo University | 10 | 2025-04-06 | 2025-06-12 |
| Perceptions of High and Low Intensity Speech Intervention in Children With a Cleft Palate High-intensity speech therapy for children with cleft palate, Low-intensity speech therapy for children with cleft palate - Cleft Lip and Palate, Cleft Palate Children | Recruiting | University Ghent | 45 | 2025-03-01 | 2026-08-24 | |
| Effect and Cost-utility of of High Intensity vs. Low Intensity Speech Intervention in Children With Cleft Palate High intensive combined phonetic-phonological intervention, Low intensive combined phonetic-phonological intervention - Cleft Palate Children, Speech Therapy | Not applicable | Recruiting | University Ghent | 70 | 2024-11-26 | 2025-01-13 |
| The Effectiveness of Adhesive Versus Conventional Nasoalveolar Molding on Children With Unilateral Cleft Lip and Palate Nasoalveolar molding in unilateral cleft lip and palate - Cleft Lip and Palate | Not applicable | Unknown | Al-Azhar University | 30 | 2024-07-20 | 2024-06-11 |
| Single Stage Versus Multiple Staged Repair of Nasal & Alveolar Deformities in Patients With Cleft Lip and Palate Rhinoplasty with or without cleft alveolus repair - Cleft Lip and Palate, Rhinoplasty | Not applicable | Recruiting | Assiut University | 40 | 2024-07-20 | 2024-07-19 |
| Evaluation of Efficiency the Full Digital Nasoalveolar Molding (F-D-NAM) on Nose and Lip Esthetics and Maxillary Arch Changes in Infants With Cleft Lip and Palate F-D-NAM - Cleft Lip and Palate | Not applicable | Completed | Cairo University | 14 | 2024-06-01 | 2026-06-22 |
| Effect of Different Nasal Stent Designs With Nasoalveolar Molding Appliance Grape Design Nasal Stent - Cleft Lip, Cleft Lip and Palate | Not applicable | Unknown | Cairo University | 28 | 2024-05-15 | 2024-05-13 |
| Customized Differential Palatal Expansion in Children With Cleft Lip and Palate Custom-Designed Palatal-Coverage Thermoplastic Aligner - Cleft Lip and Palate | Not applicable | Completed | Marmara University | 8 | 2024-05-07 | 2026-11-04 |
| Book Sharing for Toddlers With Clefts Book-Sharing for Toddlers with Clefts (BOOST) - Cleft Palate, Cleft Lip and Palate | Not applicable | Enrolling by invitation | Seattle Children's Hospital | 320 | 2024-05-01 | 2025-05-23 |
| Patient Specific Implant Versus Miniplates for Advancement of Hypoplastic Maxilla PSI, Conventional miniplates - Cleft Lip and Palate | Not applicable | Unknown | Cairo University | 20 | 2024-05-01 | 2024-04-19 |
| Liposomal Bupivacaine Use in Alveolar Bone Graft Patients Liposomal Bupivacaine, Bupivacain, Epinephrine - Cleft Lip and Palate | Phase 3 | Unknown | Kerry O'Rourke | 60 | 2024-04-24 | 2024-07-03 |
| Phase I-IIa, to Evaluate the Safety, Feasibility, and Efficacy of the Use of BIOCLEFT in the Treatment of Cleft Palate. implantation with an autologous human palatal mucosa substitute made of nanostructured fibrin-agarose generated by tissue engineering (BIOCLEFT). - Cleft Lip and Palate | Phase 1 / Phase 2 | Recruiting | Elisa María Cubiles Montero de Espinosa | 15 | 2024-04-17 | 2024-05-10 |
| Effectiveness of Dual Light Electric Toothbrush vs. Manual Toothbrush in Orthodontic Patients Undergoing Oral Surgery Toothbrush - Toothbrushing, Gingivitis | Not applicable | Recruiting | Children's Hospital Los Angeles | 198 | 2024-03-11 | 2024-05-13 |
| Effectiveness of a Customized 3D Printed Nostril Retainer Combined With Taping Vs.Taping Only on Enhancing the Nasolabial Esthetics and Maxillary Arch Dimensions in Infants With Unilateral Complete Cleft Lip and Palate. Customized 3D printed nostril retainer combined with lip taping, Lip taping - Cleft Lip and Palate | Not applicable | Unknown | Cairo University | 30 | 2024-01-30 | 2024-01-18 |
| Two Methods of Lip Taping as a Presurgical Orthopedic Appliance Lip taping - Cleft Lip and Palate | Not applicable | Unknown | University of Baghdad | 24 | 2023-01-12 | 2024-04-08 |
| Mindful Parenting - A Single Case Experimental Design Study Mindful Parenting Programme - Parenting, Alopecia | Not applicable | Unknown | Cardiff University | 12 | 2023-01-03 | 2023-03-22 |
| Effect of Performance-specific Cleft Speech Intervention and Long-term Learning in Children With a Cleft Palate Motor-phonetic intervention, Phonological intervention, Combined phonetic-phonological intervention - Cleft Palate Children, Speech Disorders in Children | Not applicable | Unknown | University Ghent | 135 | 2022-10-01 | 2023-10-27 |
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Cleft Lip (83) · Cleft Palate (13) · Communication Disorders (4) · Retrognathia (4) · Skin Diseases (2) · Agnosia (1) · Alopecia (1) · Anosmia (1) · Anxiety Disorders (1) · Attention Deficit Disorder with Hyperactivity (1) · Autism Spectrum Disorder (1) · Breast Neoplasms (1) · Burns (1) · Cicatrix (1) · Craniofacial Abnormalities (1)
Congenital Abnormalities (83) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (83) · Lip Diseases (83) · Mouth Abnormalities (83) · Mouth Diseases (83) · Stomatognathic Diseases (83) · Stomatognathic System Abnormalities (83) · Musculoskeletal Diseases (17) · Jaw Diseases (16) · Musculoskeletal Abnormalities (16) · Craniofacial Abnormalities (15) · Jaw Abnormalities (15) · Maxillofacial Abnormalities (15) · Pathological Conditions, Signs and Symptoms (12) · Nervous System Diseases (8)
Alveolar Bone Grafting (4) · Orthognathic Surgery (4) · Nasoalveolar Molding (3) · Palatal Expansion Technique (2) · Rhinoplasty (2) · Audiometry (1) · Biocompatible Materials (1) · Bite Force (1) · Bupivacaine (1) · Dexmedetomidine (1) · Drug Implants (1) · Electromyography (1) · Epinephrine (1) · Head Movements (1) · Hearing Aids (1)
Cairo University (17) · Chang Gung Memorial Hospital (4) · Faculty of Dental Medicine for Girls (4) · The University of Texas Health Science Center, Houston (4) · University Ghent (4) · University Hospital, Basel, Switzerland (3) · Assistance Publique - Hôpitaux de Paris (2) · Brno University Hospital (2) · Hospital Sirio-Libanes (2) · Pontifícia Universidade Católica de Minas Gerais (2) · University Hospital, Montpellier (2) · University of Baghdad (2) · Ain Shams University (1) · Al-Azhar University (1) · Alexandria University (1)
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Stephen Yen, DMD, PhD (2) · Adel F Hassan, Phd (1) · Alexander C Allori, MD, MPH (1) · Amany M. Diab, PhD (1) · Andrzej Brudnicki, MD DDS PhD (1) · Benitez Benito, MD DMD (1) · Benito K Benitez, MD DDS MHBA (1) · Benito K Benitez, MD DMD (1) · Brent Collett, PhD (1) · Brett T Chiquet, DDS (1) · Carroll-Ann Trotman, BDS, MA, MS (1) · Chad A. Purnell, MD (1) · Chelsea Wehr, DDS (1)
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R01DE013814 (1)