5 not yet recruiting, 4 recruiting, 2 completed, 2 enrolling by invitation. 14 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 14 | Not yet recruiting 5, Recruiting 4, Completed 2, Enrolling by invitation 2, Unknown 1 |
Follow Chronic Rhinosinusitis (CRS): new trials by email Literature Review of Chronic Rhinosinusitis (CRS) trials Research Report on Chronic Rhinosinusitis (CRS)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Position-Directed Budesonide Nasal Drops for CRS-associated Olfactory Dysfunction Nasal Drops, Nasal Spray - Chronic Rhinosinusitis (CRS), Olfactory Dysfunction | Not applicable | Not yet recruiting | Peking University Third Hospital | 78 | 2026-09-25 | 2026-09-16 |
| Pistacia Lentiscus Oil Nasal Spray With Reduced-Dose Mometasone in Chronic Rhinosinusitis Mometasone furoate - intranasal application, Bactorinol nasal spray - Chronic Rhinosinusitis (CRS) | Not applicable | Not yet recruiting | Liaquat University of Medical & Health Sciences | 64 | 2026-09-07 | 2026-08-26 |
| Active vs. Passive VR During Office-based ENT Procedures Passive virtual reality headset or goggles, Active virtual reality headset or goggles - Pain, Anxiety | Not applicable | Not yet recruiting | Cedars-Sinai Medical Center | 132 | 2026-09-01 | 2026-08-17 |
| Evaluation of the Safety and Performance of a Bioresorbable Nasal Dressing Containing Mometasone Furoate (MF) OCEAN, Steroid-eluting sinus stent - Chronic Rhinosinusitis (CRS), Chronic Rhinosinusitis (CRS) With and Without Nasal Polyps | Not applicable | Enrolling by invitation | Polyganics BV | 110 | 2026-03-19 | 2026-06-25 |
| Cognitive and Immunologic Profiles of Patients With Olfactory Dysfunction After Smell Training Smell Training - Smell Loss, Chronic Rhinosinusitis (CRS) | Not applicable | Recruiting | The Cleveland Clinic | 52 | 2025-12-09 | 2026-07-02 |
| Efficacy of Lavender Aromatherapy on Anxiety and Pain Reduction During Awake Otolaryngologic Procedures Lavender Aromatherapy, Placebo Aromatherapy - Inferior Turbinate Hypertrophy, Chronic Rhinosinusitis (CRS) | Not applicable | Recruiting | Cedars-Sinai Medical Center | 184 | 2025-12-01 | 2025-12-23 |
| Assessement of Effectiveness of Seawater Nasal Sprays on Sinonasal Symptoms Respimer® Hygiene-Prevention -Baby, kids, adults, Respimer® Hygiene-Prevention Kids, adults, Respimer® Decongestion Baby, kids, adults - URTI, Bronchiolitis | Not applicable | Recruiting | Laboratoire de la Mer | 1065 | 2025-08-27 | 2025-12-03 |
| Treatment Decision-Making Among Patients With Chronic Rhinosinusitis Patient Centered CRS Treatment Decision Support - Chronic Rhinosinusitis (CRS) | Not applicable | Enrolling by invitation | University of Southern California | 50 | 2025-06-02 | 2025-12-18 |
| Trans-nasal Sphenopalatine Ganglion Block for Prevention of Emergence Agitation Following Functional Endoscopic Sinus Surgery Bilateral Trans-nasal Sphenopalatine Ganglion Block, Sham Trans-nasal Injection - Chronic Rhinosinusitis (CRS), Emergence Agitation | Not applicable | Completed | Mansoura University | 100 | 2025-01-05 | 2026-06-12 |
| Endoscopic Direct "Draf IIa" (Carolyn's Window Approach) Versus Endoscopic Angled "Draf IIa"Approach in Chronic Rhinosinusitis With Frontal Sinus Affection ( A Comparative Study ). Endoscopic direct Draf IIa, Endoscopic angled Draf IIa - Chronic Rhinosinusitis (CRS), Frontal Sinusitis | Not applicable | Not yet recruiting | Assiut University | 68 | 2025-01-01 | 2024-10-31 |
| Xiangtong TM Full Degradation Sinus Drug Stent System Prospective, Open, Single-center, Randomized Controlled Clinical Trial Xiangtong TM full degradation sinus drug stent system, nasopore - Chronic Rhinosinusitis (CRS) | Not applicable | Not yet recruiting | The First Affiliated Hospital with Nanjing Medical University | 50 | 2024-12-01 | 2024-11-01 |
| Comparative Effects of Therapeutic Ultrasound and Sinus Massage in Chronic Rhinosinusitis: a Randomized Controlled Study Therapeutic Ultrasound, Sinus Massage, Control group - Chronic Rhinosinusitis (CRS) | Not applicable | Recruiting | Foundation University Islamabad | 60 | 2024-07-18 | 2025-05-07 |
| Dexamethasone Phonophoresis Versus Laser Acupuncture on Chronic Rhinosinusitis Dexamethasone phonophoresis, Laser Acupuncture, Traditional medication - Chronic Rhinosinusitis (CRS) | Not applicable | Unknown | Cairo University | 90 | 2024-07-01 | 2024-09-27 |
| Effect of Pleuran on the Clinical Course of Patients With Chronic Rhinosinusitis Imunoglukan P4H® capsules - Chronic Rhinosinusitis (CRS), Exacerbations | Not applicable | Completed | Pleuran, s.r.o. | 85 | 2022-11-01 | 2026-03-10 |
Nasal Polyps (2) · Anosmia (1) · Anxiety Disorders (1) · Bronchiolitis (1) · COVID-19 (1) · Dysphonia (1) · Emergence Delirium (1) · Frontal Sinusitis (1) · Nasal Obstruction (1) · Pain (1) · Pain, Postoperative (1) · Respiratory Tract Infections (1) · Rhinitis, Allergic (1) · Rhinitis, Vasomotor (1) · Thyroid Nodule (1)
Respiratory Tract Diseases (6) · Nose Diseases (5) · Otorhinolaryngologic Diseases (5) · Infections (3) · Nervous System Diseases (3) · Neurologic Manifestations (3) · Pathological Conditions, Signs and Symptoms (3) · Signs and Symptoms (3) · Mental Disorders (2) · Pathological Conditions, Anatomical (2) · Polyps (2) · Respiratory Tract Infections (2) · Rhinitis (2) · Airway Obstruction (1) · Bronchial Diseases (1)
Control Groups (1) · Eye Protective Devices (1) · Olfactory Training (1) · Tobacco Use Cessation Devices (1) · Ultrasonic Therapy (1)
Cedars-Sinai Medical Center (2) · Assiut University (1) · Cairo University (1) · Foundation University Islamabad (1) · Laboratoire de la Mer (1) · Liaquat University of Medical & Health Sciences (1) · Mansoura University (1) · Peking University Third Hospital (1) · Pleuran, s.r.o. (1) · Polyganics BV (1) · The Cleveland Clinic (1) · The First Affiliated Hospital with Nanjing Medical University (1) · University of Southern California (1)
United States (5) · Egypt (2) · China (1) · Czechia (1) · France (1) · Italy (1) · Pakistan (1) · Slovakia (1)
Amir Mostafa Shabana, MD (1) · Ankona Ghosh, MD (1) · Mohamad Chaaban, MD (1) · Shinyi Wu, PhD (1)