90 completed. 90 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 90 | Completed 90 |
Follow Chronic Obstructive Pulmonary Disease: new trials by email Literature Review of Chronic Obstructive Pulmonary Disease trials Research Report on Chronic Obstructive Pulmonary Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase 4 COPD and Suboptimal Inspiratory Flow Rate Revefenacin, Tiotropium, Revefenacin Placebo - Chronic Obstructive Pulmonary Disease | Phase 4 | Completed | Theravance Biopharma | 404 | 2022-01-07 | 2024-12-20 |
| CHF5993 and CHF1535 pMDI on Lung Hyperinflation and Exercise Endurance Time in Subjects With COPD CHF5993, CHF1535, Matched placebo - Chronic Obstructive Pulmonary Disease | Phase 4 | Completed | Chiesi Farmaceutici S.p.A. | 106 | 2021-10-28 | 2023-03-24 |
| Comparison of Time to Extubation Using Sugammadex or Neostigmine neostigmine/glycopyrrolate, sugammadex - Neuromuscular Blockade, Chronic Obstructive Pulmonary Disease | Phase 4 | Completed | Temple University | 58 | 2021-04-08 | 2024-03-13 |
| Bacillus Calmette-guérin Vaccination to Prevent COVID-19 BCG vaccine, Placebo - COVID-19, Virus Diseases | Phase 4 | Completed | Hellenic Institute for the Study of Sepsis | 301 | 2020-05-26 | 2021-05-11 |
| Association of Cathelicidin and Vitamin D Levels With the Category and Course of COPD Cholecalciferol Liquid - Chronic Obstructive Pulmonary Disease, Chronic Obstructive Pulmonary Disease Moderate | Phase 4 | Completed | Karaganda Medical University | 120 | 2020-02-18 | 2024-04-12 |
| Effects of Spiolto® Respimat® (Tiotropium/Olodaterol) on Cardiac Function in Hyperinflated COPD Subjects Olodaterol-Tiotropium - Chronic Obstructive Pulmonary Disease | Phase 4 | Completed | Fraunhofer-Institute of Toxicology and Experimental Medicine | 32 | 2020-01-28 | 2023-04-26 |
| Effects of HFOT on Exercise Performance in Patients With COPD. A Randomized, Controlled Trial. High-flow oxygen therapy (HFOT), Low-flow oxygen therapy (LFOT) - Chronic Obstructive Pulmonary Disease | Phase 4 | Completed | University of Zurich | 79 | 2019-05-20 | 2020-02-06 |
| Beta-blockers to Patients With Chronic Obstructive Pulmonary Disease Metoprolol, Standard care - Chronic Obstructive Pulmonary Disease | Phase 4 | Completed | Ole Frobert, MD, PhD | 1713 | 2018-06-12 | 2026-08-12 |
| Effect of Acetazolamide on Lung Water Content by Ultrasound in Patients With Respiratory Disease at Altitude ACETAZOLAMIDE oral capsule, Placebo oral capsule - Chronic Obstructive Pulmonary Disease | Phase 4 | Completed | University of Zurich | 112 | 2018-05-22 | 2021-11-05 |
| Differential Mechanisms of Dyspnea Relief in Advanced COPD: Opiates vs. Bronchodilators Fentanyl Citrate, Combivent - Chronic Obstructive Pulmonary Disease | Phase 4 | Completed | Dr. Denis O'Donnell | 20 | 2017-09-20 | 2024-04-03 |
| Clinical Trial of Efficacy and Safety of Rengalin in the Treatment of Cough in Patients With Chronic Obstructive Pulmonary Disease Rengalin, Placebo - Chronic Obstructive Pulmonary Disease | Phase 4 | Completed | Materia Medica Holding | 238 | 2017-06-16 | 2020-12-11 |
| INvestigating COPD Outcomes, Genomics and Neutrophilic Inflammation With Tiotropium and Olodaterol Tiotropium & olodaterol, fluticasone furoate & vilanterol - Chronic Obstructive Pulmonary Disease | Phase 4 | Completed | University of Dundee | 80 | 2017-06-01 | 2020-07-20 |
| Effect of Acetazolamide on Exercise Performance in Patients With Respiratory Disease at Altitude ACETAZOLAMIDE oral capsule, Placebo oral capsule - Chronic Obstructive Pulmonary Disease | Phase 4 | Completed | University of Zurich | 176 | 2017-05-24 | 2019-08-16 |
| Effect of Acetazolamide on Postural Control in Patients With Respiratory Disease at Altitude ACETAZOLAMIDE oral capsule, Placebo oral capsule - Chronic Obstructive Pulmonary Disease | Phase 4 | Completed | University of Zurich | 127 | 2017-05-24 | 2021-10-12 |
| Effect of Acetazolamide on Right Ventricular Function at Rest in Patients With Respiratory Disease at Altitude ACETAZOLAMIDE oral capsule, Placebo oral capsule - Chronic Obstructive Pulmonary Disease | Phase 4 | Completed | University of Zurich | 110 | 2017-05-24 | 2019-08-14 |
| Effect of Acetazolamide on Right Ventricular Function During Exercise in Patients With Respiratory Disease at Altitude ACETAZOLAMIDE oral capsule, Placebo oral capsule - Chronic Obstructive Pulmonary Disease | Phase 4 | Completed | University of Zurich | 110 | 2017-05-24 | 2019-08-14 |
| Effect of Acetazolamide on Sleep Related Breathing Disturbances in Patients With Respiratory Disease at Altitude ACETAZOLAMIDE oral capsule, Placebo oral capsule - Chronic Obstructive Pulmonary Disease | Phase 4 | Completed | University of Zurich | 185 | 2017-05-24 | 2019-01-29 |
| The Effect of STIOLTO™ RESPIMAT® on Fatigue in Chronic Obstructive Pulmonary Disease Stiolto Respimat, Placebo Respimat - Chronic Obstructive Pulmonary Disease | Phase 4 | Completed | Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | 14 | 2017-03-01 | 2020-08-06 |
| Effects of Dual Bronchodilator Treatment on Cardiopulmonary Interactions in COPD Tiotropium + Olodaterol, PLACEBO - Chronic Obstructive Pulmonary Disease | Phase 4 | Completed | Queen's University | 25 | 2017-01-01 | 2019-02-05 |
| Microbiome Use to Stratify Use of Inhaled Corticosteroids: MUSIC Trial Budesonide & formoterol fumarate and Aclidinium bromide, Fluticasone 500 & salmeterol and Aclidinium bromide, Fluticasone 250 & salmeterol and Aclidinium bromide - Chronic Obstructive Pulmonary Disease | Phase 4 | Completed | University of Dundee | 158 | 2016-12-01 | 2020-07-20 |
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Pulmonary Disease, Chronic Obstructive (90) · Emphysema (10) · Motor Activity (7) · Dyspnea (5) · Lung Diseases, Obstructive (5) · Bronchitis (4) · Lung Diseases (4) · Asthma (3) · Bronchitis, Chronic (3) · Inflammation (2) · Respiratory Tract Diseases (2) · Anxiety Disorders (1) · Bronchiolitis Obliterans Syndrome (1) · COVID-19 (1) · Cardiovascular Diseases (1)
Chronic Disease (90) · Disease Attributes (90) · Pathologic Processes (90) · Pathological Conditions, Signs and Symptoms (90) · Respiratory Tract Diseases (88) · Lung Diseases (86) · Lung Diseases, Obstructive (85) · Bronchial Diseases (11) · Behavior (10) · Infections (9) · Respiratory Tract Infections (8) · Respiration Disorders (6) · Signs and Symptoms (5) · Signs and Symptoms, Respiratory (5) · Bronchitis (4)
Tiotropium Bromide (13) · Budesonide (7) · Formoterol Fumarate (7) · Glycopyrrolate (7) · indacaterol (7) · Acetazolamide (6) · Salmeterol Xinafoate (6) · Fluticasone (5) · tiotropium-olodaterol (4) · Albuterol (3) · Fluticasone-Salmeterol Drug Combination (3) · aclidinium bromide (3) · indacaterol-glycopyrronium combination (3) · Albuterol, Ipratropium Drug Combination (2) · Bisoprolol (2)
Novartis Pharmaceuticals (10) · University of Zurich (7) · AstraZeneca (5) · University of Dundee (4) · Queen's University (3) · Dartmouth-Hitchcock Medical Center (2) · Imperial College London (2) · Laval University (2) · Sumitomo Pharma America, Inc. (2) · Ataturk University (1) · Baqiyatallah Medical Sciences University (1) · Centre Hospitalier Universitaire de Besancon (1) · Chiesi Farmaceutici S.p.A. (1) · Dr. Denis O'Donnell (1) · Eisai Co., Ltd. (1)
United Kingdom (16) · United States (13) · Canada (12) · Germany (9) · Kyrgyzstan (7) · Spain (7) · Brazil (5) · Belgium (4) · Denmark (4) · Italy (4) · Netherlands (4) · Russia (4) · Sweden (4) · Switzerland (3) · Argentina (2)
Talant M Sooronbaev, MD (6) · Konrad E Bloch, MD (5) · Silvia Ulrich, MD (3) · Denis E O'Donnell, MD (2) · James Chalmers, MBChB, MRCP (2) · Aina Noguera, Medicine (1) · Aklak B Choudhury, MRCP (1) · Aleksander V Zhestkov, Professor (1) · Alyn H Morice, Professor (1) · Amanda Iglesias, Biology (1) · Ana Moragas, Family doc. (1) · Andrei D Protasov, Professor (1)
PMID 15229100, PMID 16113473, PMID 16235327, PMID 17646228, PMID 17951276, PMID 18162137, PMID 18584227, PMID 18804362, PMID 19208459, PMID 19245725, PMID 19532028, PMID 19711095, PMID 19808130, PMID 19875684, PMID 19875685, PMID 19878590, PMID 20040610, PMID 20498416, PMID 20576731, PMID 20692140, PMID 21145720, PMID 21558357, PMID 22250141, PMID 22791991, PMID 22923662, PMID 23682979, PMID 23715032, PMID 23807094, PMID 24484754, PMID 24549160, PMID 25504992, PMID 25673981, PMID 25684586, PMID 26152326, PMID 26549785, PMID 26719947, PMID 26752024, PMID 26917577, PMID 27174882, PMID 27239929, PMID 27812637, PMID 27940287, PMID 28679611, PMID 28877027, PMID 29025008, PMID 29488477, PMID 29625777, PMID 29763572, PMID 29797235, PMID 30138422
2017 (6), 2016 (2), 2009 (1), 2015 (1)