9 completed, 2 recruiting, 2 unknown, 1 active not recruiting. 14 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 14 | Completed 9, Recruiting 2, Unknown 2, Active not recruiting 1 |
Follow Chronic Cough: new trials by email Literature Review of Chronic Cough trials Research Report on Chronic Cough
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Finnish Children´s Protracted Cough Fluticasone propionate inhalation, Amoxicillin-clavulanic acid oral suspension, Placebo inhalation - Chronic Cough | Phase 3 | Recruiting | Tampere University Hospital | 100 | 2025-12-22 | 2026-05-13 |
| A 24-Week Study of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough - China Extension BLU-5937, Placebo - Refractory Chronic Cough | Phase 3 | Recruiting | GlaxoSmithKline | 75 | 2025-11-21 | 2026-06-16 |
| A 24-Week Study of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough BLU-5937, Placebo - Cough, Refractory Chronic Cough | Phase 3 | Active not recruiting | Bellus Health Inc. - a GSK company | 997 | 2022-12-05 | 2026-07-14 |
| A 52-Week Study of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough BLU-5937, Placebo - Cough, Refractory Chronic Cough | Phase 3 | Completed | Bellus Health Inc. - a GSK company | 957 | 2022-10-25 | 2026-07-14 |
| Efficacy of SLN Block for Chronic Cough Superior laryngeal nerve block, Injection of placebo (saline), Injection of steroid-lidocaine mixture - Cough, Superior Laryngeal Nerve Block | Phase 3 | Completed | Medical University of South Carolina | 17 | 2020-07-22 | 2025-10-23 |
| Efficacy and Safety of Gefapixant (MK-7264) in Adult Participants With Recent Onset Chronic Cough (MK-7264-043) Gefapixant, Placebo - Chronic Cough | Phase 3 | Completed | Merck Sharp & Dohme LLC | 419 | 2020-05-21 | 2023-05-16 |
| Efficacy and Safety of Gefapixant (MK-7264) in Women With Chronic Cough and Stress Urinary Incontinence (MK-7264-042) Gefapixant, Placebo - Chronic Cough | Phase 3 | Completed | Merck Sharp & Dohme LLC | 376 | 2020-05-10 | 2024-11-05 |
| A Study of Gefapixant (MK-7264) in Adult Participants With Chronic Cough (MK-7264-030)-China Extension Gefapixant 45 mg twice daily (BID), Gefapixant 15 mg BID, Placebo - Chronic Cough | Phase 3 | Completed | Merck Sharp & Dohme LLC | 161 | 2019-05-17 | 2024-01-12 |
| A Study of Gefapixant (MK-7264) in Japanese Adult Participants With Refractory or Unexplained Chronic Cough (MK-7264-038) Gefapixant, Placebo - Chronic Cough | Phase 3 | Completed | Merck Sharp & Dohme LLC | 175 | 2018-10-31 | 2021-11-01 |
| Indomethacin for Refractory Chronic Cough indomethacin, Placebo, Omeprazole - Refractory Chronic Cough | Phase 3 | Unknown | The First Affiliated Hospital of Guangzhou Medical University | 84 | 2018-10-22 | 2018-11-26 |
| A Study of Gefapixant (MK-7264) in Adult Participants With Chronic Cough (MK-7264-030) Placebo, Gefapixant 15 mg BID, Gefapixant 45 mg BID - Chronic Cough | Phase 3 | Completed | Merck Sharp & Dohme LLC | 1317 | 2018-03-15 | 2021-09-02 |
| A Study of Gefapixant (MK-7264) in Adult Participants With Chronic Cough (MK-7264-027) Placebo, Gefapixant - Chronic Cough | Phase 3 | Completed | Merck Sharp & Dohme LLC | 732 | 2018-03-14 | 2021-06-16 |
| An Open Label Trial of Azithromycin in Chronic Productive Cough Azithromycin - Chronic Cough | Phase 3 | Unknown | University of Nottingham | 50 | 2013-12-01 | 2016-02-18 |
| The Effect of Azithromycin in Patients With Chronic Obstructive Pulmonary Disease (COPD) and Chronic Productive Cough azithromycin, placebo - Cough, Chronic Obstructive Pulmonary Disease | Phase 3 | Completed | Isala | 84 | 2009-09-01 | 2015-09-18 |
Cough (8) · Respiration Disorders (4) · Respiratory Tract Diseases (4) · Signs and Symptoms, Respiratory (4) · Signs and Symptoms (2) · Bronchitis (1) · Bronchitis, Chronic (1) · Pulmonary Disease, Chronic Obstructive (1) · Urinary Incontinence, Stress (1)
Pathological Conditions, Signs and Symptoms (14) · Signs and Symptoms (12) · Respiration Disorders (10) · Respiratory Tract Diseases (10) · Signs and Symptoms, Respiratory (10) · Cough (6) · Bronchial Diseases (2) · Infections (2) · Lung Diseases (2) · Lung Diseases, Obstructive (2) · Respiratory Tract Infections (2) · Bronchitis (1) · Chronic Disease (1) · Disease Attributes (1) · Female Urogenital Diseases (1)
Gefapixant (6) · BLU-5937 (3) · Azithromycin (2) · BID protein, human (2) · Epinephrine (1) · Indomethacin (1) · Lidocaine (1) · Omeprazole (1) · Sodium Chloride (1) · Triamcinolone (1)
Merck Sharp & Dohme LLC (6) · Bellus Health Inc. - a GSK company (2) · GlaxoSmithKline (1) · Isala (1) · Medical University of South Carolina (1) · Tampere University Hospital (1) · The First Affiliated Hospital of Guangzhou Medical University (1) · University of Nottingham (1)
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Courtney Tipton (1) · Tim Harrison, MD, FRCP (1)
PMID 35248186, PMID 35569802, PMID 22230731, PMID 24229360, PMID 30722097, PMID 35752582, PMID 36879087, PMID 39222649, PMID 39706278
2017 (2), 2019 (2), 2025 (1)