13 completed, 2 terminated, 2 unknown, 1 not yet recruiting. 20 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 20 | Completed 13, Terminated 2, Unknown 2, Not yet recruiting 1, Recruiting 1, Withdrawn 1 |
| Phase 2 | 1 | Withdrawn 1 |
Follow Chlamydia Infections: new trials by email Literature Review of Chlamydia Infections trials Research Report on Chlamydia Infections
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Clinical Study to Assess the Efficacy of Weekly Doxycycline Prophylaxis to Reduce Bacterial Sexually Transmitted Infections (STI) in Young African Women Doxycycline hyclate, Standard of Care for STI prevention - Sexually Transmitted Infection (STI), Gonorrhea | Phase 3 | Not yet recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 580 | 2026-11-30 | 2026-10-20 |
| STI Testing to Enhance PrEP Use in Pregnancy Chlamydia trachomatis, Neisseria gonorrhoeae and Trichomonas vaginalis testing - PrEP Adherence, Sexually Transmitted Infections (STIs) | Phase 3 | Recruiting | Botswana Harvard AIDS Institute Partnership | 600 | 2025-06-18 | 2026-06-11 |
| Evaluation of EVO100 for Prevention of Urogenital Chlamydia Trachomatis and Neisseria Gonorrhoeae Infection EVO100, Placebo - Sexually Transmitted Diseases, Gonorrhea | Phase 3 | Completed | Evofem Inc. | 1892 | 2020-10-15 | 2024-01-30 |
| Safety of Co-administration of IDA and Azithromycin for NTDs ( ComboNTDs ) Albendazole on Day 1, Ivermectin on Day 1, Diethylcarbamazine on day 1 - Trachoma, Yaws | Phase 3 | Completed | Lihir Medical Centre | 20000 | 2018-10-01 | 2019-02-28 |
| Sanitation, Water, and Instruction in Face-washing for Trachoma I/II Water, sanitation, and hygiene (WASH) intervention, Standard of care WASH intervention, Azithromycin - Trachoma | Phase 3 | Completed | University of California, San Francisco | 47605 | 2015-12-05 | 2026-06-04 |
| Nepal Elimination of Trachoma Study Azithromycin - Trachoma | Phase 2 / Phase 3 | Withdrawn | University of California, San Francisco | 2014-08-01 | 2015-05-21 | |
| Efficacy and Safety Study of Oral Solithromycin Compared to Intramuscular Ceftriaxone Plus Oral Azithromycin in the Treatment of Patients With Gonorrhea solithromycin, ceftriaxone, azithromycin - Uncomplicated Urogenital Gonorrhea | Phase 3 | Completed | Melinta Therapeutics, Inc. | 264 | 2014-08-01 | 2017-09-11 |
| Identigene STD Test Collection Kit Validation Study STD Diagnostic Kit (Identigene) - Infection | Phase 3 | Unknown | Identigene | 3000 | 2011-11-01 | 2013-06-03 |
| Treatment of Chlamydia Infection Comparing WC2031 Tablets With Vibramycin Doxycyline Hyclate tablet, Vibramycin (doxycyline hyclate) capsule - Urogential Chlamydia Trachomatis Infection | Phase 3 | Completed | Warner Chilcott | 495 | 2010-04-01 | 2012-01-27 |
| Empiric Therapy of Mucopurulent Cervicitis (MPC) Placebo, Azithromycin, Cefixime - Vaginitis Bacterial, Cervicitis | Phase 3 | Terminated | National Institute of Allergy and Infectious Diseases (NIAID) | 87 | 2010-03-01 | 2014-12-24 |
| Treatment Failure of Chlamydial Infection in Males and Females in Youth Correctional Facilities Azithromycin, Doxycycline - Chlamydial Infection | Phase 3 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 567 | 2009-12-02 | 2026-08-05 |
| Bacterial Vaginosis Home Screening to Prevent STDs Metronidazole - Bacterial Vaginosis | Phase 3 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 1370 | 2008-07-28 | 2020-02-18 |
| HIV and STD Prevention for High-Risk, Inner-City, African American Youth Social Skills Training, Mass media, Control - HIV Infections, Sexually Transmitted Diseases | Phase 3 | Completed | University of Pennsylvania | 1650 | 2006-10-01 | 2012-01-19 |
| Combination Antibiotic Treatment for Reactive Arthritis Caused by Chlamydia Bacteria Doxycycline and Rifampin, Azithromycin and Rifampin, Placebo - Arthritis, Reactive, Reiter Disease | Phase 3 | Completed | University of South Florida | 42 | 2006-05-01 | 2018-11-13 |
| Trial to Evaluate PRO 2000/5 Gels for the Prevention of Vaginally Acquired HIV Infection PRO 2000/5, Placebo - HIV Infections, Gonorrhea | Phase 3 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 9404 | 2005-10-01 | 2012-09-10 |
| Cellulose Sulfate (CS) Gel and HIV in Nigeria Cellulose Sulfate Vaginal Gel (Microbicide) - HIV Infections, Gonorrhea | Phase 3 | Terminated | FHI 360 | 2160 | 2004-11-01 | 2007-02-28 |
| Efficacy and Safety of 2 Dosing Regimens of T1225 Eye Drops 1.5% Versus Oral Azithromycin in Treatment of Trachoma Azithromycin - Trachoma | Phase 3 | Completed | Laboratoires Thea | 2004-01-01 | 2006-07-26 | |
| Trial of Male Circumcision: HIV, Sexually Transmitted Disease (STD) and Behavioral Effects in Men, Women and the Community Male circumcision - HIV Infections, Sexually Transmitted Diseases | Phase 3 | Unknown | Wawer, Maria J., M.D. | 5200 | 2003-08-01 | 2007-08-10 |
| Partner Notification for Chlamydia in Primary Care Practice nurse-led partner notification, Referral to specialist genitourinary clinic - Chlamydia Infections | Phase 3 | Completed | University of Bristol | 214 | 2001-03-01 | 2018-01-17 |
| Clinical Trial of Eye Prophylaxis in the Newborn Erythromycin Ointment, Silver Nitrate Drops - Chlamydia Infections, Ophthalmia Neonatorum | Phase 3 | Completed | National Eye Institute (NEI) | 1985-01-01 | 2009-09-17 |
Gonorrhea (10) · Sexually Transmitted Diseases (6) · HIV Infections (4) · Trachoma (4) · Vaginosis, Bacterial (3) · Herpes Genitalis (2) · Syphilis (2) · Acquired Immunodeficiency Syndrome (1) · Arthritis, Reactive (1) · Elephantiasis, Filarial (1) · Infections (1) · Neglected Diseases (1) · Ophthalmia Neonatorum (1) · Papillomavirus Infections (1)
Bacterial Infections (20) · Bacterial Infections and Mycoses (20) · Chlamydiaceae Infections (20) · Gram-Negative Bacterial Infections (20) · Infections (19) · Communicable Diseases (16) · Genital Diseases (16) · Sexually Transmitted Diseases, Bacterial (16) · Urogenital Diseases (16) · Neisseriaceae Infections (11) · Sexually Transmitted Diseases (10) · Disease Attributes (8) · Pathologic Processes (8) · Pathological Conditions, Signs and Symptoms (8) · Conjunctival Diseases (5)
Azithromycin (8) · Doxycycline (4) · Albendazole (1) · Anti-Infective Agents (1) · Capsules (1) · Cefixime (1) · Ceftriaxone (1) · Circumcision, Male (1) · Diethylcarbamazine (1) · Health (1) · Hygiene (1) · Ivermectin (1) · Methods (1) · Metronidazole (1) · Placebo Effect (1)
National Institute of Allergy and Infectious Diseases (NIAID) (4) · University of California, San Francisco (2) · Botswana Harvard AIDS Institute Partnership (1) · Endo USA Inc., a Keenova Therapeutics Company (1) · Evofem Inc. (1) · FHI 360 (1) · Identigene (1) · Laboratoires Thea (1) · Lihir Medical Centre (1) · Melinta Therapeutics, Inc. (1) · National Eye Institute (NEI) (1) · University of Bristol (1) · University of Pennsylvania (1) · University of South Florida (1) · Warner Chilcott (1)
United States (9) · Uganda (3) · Botswana (2) · Australia (1) · Canada (1) · Eswatini (1) · Ethiopia (1) · Malawi (1) · Nepal (1) · Nigeria (1) · Papua New Guinea (1) · South Africa (1) · Tanzania (1) · United Kingdom (1) · Zambia (1)
Bruce D Gaynor, MD (1) · Catherine Maher, PhD (1) · Daniel Romer, PhD (1) · David Serwadda, MBChB,MPH (1) · Dionna M Wittberg, MPH (1) · Godfrey Kigozi, MBChB, MPH (1) · Jeremy D Keenan, MD, MPH (1) · John Caminis, MD (1) · John D. Carter, MD (1) · Lars Mouritsen, PhD (1) · Lawrence Brown, MD (1) · Lucy John, MD (1) · Marcus Chen, MD, PhD (1) · Mike Smith (1)
PMID 16356945, PMID 18532873, PMID 19023429, PMID 19220138, PMID 19321868, PMID 19389002, PMID 19549331, PMID 19616720, PMID 19936044, PMID 20155838, PMID 20370481, PMID 21216000, PMID 21489882, PMID 22431798, PMID 23153149, PMID 26611782, PMID 26699167, PMID 31196813, PMID 31380687, PMID 33619183, PMID 34919861, PMID 35418329, PMID 38134305, PMID 38991011, PMID 41314021, PMID 41548574
K23EY019881 (1), R21AR053646 (1), U01MH066809 (1), U10EY023939 (1)