17 completed, 7 terminated, 6 unknown, 1 active not recruiting. 11 Phase 2, 8 Not applicable, 5 Phase 3, 3 Phase 1, 1 Phase 4.
Follow Chemotherapeutic Agent Toxicity: new trials by email Literature Review of Chemotherapeutic Agent Toxicity trials Research Report on Chemotherapeutic Agent Toxicity
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Malnutrition and Sarcopenia Screening in Chemotherapy Patients Nutrition Aspect of Cancer, Sarcopenia | Active not recruiting | Çanakkale Onsekiz Mart University | 200 | 2025-07-01 | 2025-09-09 | |
| Investigating Paclitaxel Toxicity in Breast Cancer: the Roles of Physical Activity and Body Composition. Paclitaxel Chemotherapy - Breast Cancer, Paclitaxel Adverse Reaction | Recruiting | Universitair Ziekenhuis Brussel | 40 | 2024-07-30 | 2024-11-01 | |
| Telemonitoring Platforms and Chemotherapy-Associated Toxicity Contigo Application - Cancer, Chemotherapeutic Agent Toxicity | Not applicable | Unknown | Universidad Nacional Andres Bello | 80 | 2024-04-01 | 2024-04-08 |
| Diminish Chemotherapy Related Side Effects Through Patient Education Educational Brochure - Chemotherapeutic Toxicity, Chemotherapeutic Agent Toxicity | Not applicable | Completed | Milton S. Hershey Medical Center | 36 | 2021-03-24 | 2023-09-01 |
| Mobile App for Symptoms Monitoring in Cancer Patients: a Pilot Study Mentora app - Cancer, Symptoms and Signs | Not applicable | Unknown | Associacao de Investigacao de Cuidados de Suporte em Oncologia | 30 | 2021-02-01 | 2021-01-12 |
| Cryotherapy vs. Cryocompression for Preventing Chemotherapy-induced-peripheral-neuropathy in Women Undergoing Chemotherapy Hilotherm Chemo Care - Chemotherapy-induced Peripheral Neuropathy, Chemotherapeutic Toxicity | Not applicable | Unknown | Medical University Innsbruck | 196 | 2020-02-03 | 2020-11-17 |
| Sublingual Anvirzel in Advance Non-Small Cell Lung Cancer (NSCLC) Carboplatin, Docetaxel, Anvirzel - Chemotherapeutic Agent Toxicity, Lung Cancer | Phase 1 | Withdrawn | M.D. Anderson Cancer Center | 2014-06-01 | 2015-06-08 | |
| Glutamine in Preventing Peripheral Neuropathy in Patients With Multiple Myeloma Receiving Bortezomib glutamine, quality-of-life assessment, placebo - Chemotherapeutic Agent Toxicity, Multiple Myeloma | Phase 2 | Terminated | Beth Faiman | 9 | 2013-02-01 | 2019-10-22 |
| Rituximab, Methotrexate, Vincristine Sulfate, Procarbazine Hydrochloride, and Cytarabine With or Without Radiation Therapy in Treating Patients With Primary Central Nervous System Lymphoma Rituximab, Cytarabine, Methotrexate - Chemotherapeutic Agent Toxicity, Cognitive/Functional Effects | Phase 2 | Completed | Radiation Therapy Oncology Group | 91 | 2011-09-01 | 2023-07-20 |
| Cryotherapy in Preventing Peripheral Neuropathy and Nail Toxicity in Patients With Breast Cancer Who Are Receiving Paclitaxel cryotherapy, questionnaire administration, quality-of-life assessment - Chemotherapeutic Agent Toxicity, Pain | Not applicable | Terminated | Northwestern University | 33 | 2010-11-03 | 2019-08-20 |
| Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity in Patients With Colon Cancer or Rectal Cancer Receiving Oxaliplatin-Based Combination Chemotherapy calcium gluconate, magnesium sulfate, placebo - Chemotherapeutic Agent Toxicity, Colorectal Cancer | Phase 3 | Completed | Alliance for Clinical Trials in Oncology | 362 | 2010-06-01 | 2022-11-03 |
| Glutathione in Preventing Peripheral Neuropathy Caused by Paclitaxel and Carboplatin in Patients With Ovarian Cancer, Fallopian Tube Cancer, and/or Primary Peritoneal Cancer Carboplatin, Glutathione, Laboratory Biomarker Analysis - Chemotherapeutic Agent Toxicity, Neuropathy | Phase 3 | Completed | Alliance for Clinical Trials in Oncology | 195 | 2009-12-01 | 2017-02-23 |
| S0715: Acetyl-L-Carnitine in Preventing Neuropathy in Women With Stage I, II, or IIIA Breast Cancer Undergoing Chemo acetyl-L-carnitine hydrochloride, placebo - Breast Cancer, Chemotherapeutic Agent Toxicity | Phase 3 | Completed | SWOG Cancer Research Network | 437 | 2009-09-01 | 2017-08-14 |
| First-Line Chemotherapy With or Without Neuromuscular Electrical Stimulation in Treating Patients With Non-Small Cell Lung Cancer carboplatin, vinorelbine tartrate, neuromuscular electrical stimulation - Chemotherapeutic Agent Toxicity, Fatigue | Phase 2 | Unknown | Wales Cancer Trials Unit | 52 | 2009-09-01 | 2011-08-08 |
| Electrical Stimulation Therapy Using the MC5-A Scrambler in Reducing Peripheral Neuropathy Caused by Chemotherapy questionnaire administration, Sensory Neuropathy Scale instrument, Quality of Life instrument - Chemotherapeutic Agent Toxicity, Neurotoxicity | Phase 2 | Completed | Virginia Commonwealth University | 18 | 2009-06-12 | 2017-03-29 |
| Selenomethionine in Reducing Mucositis in Patients With Locally Advanced Head and Neck Cancer Who Are Receiving Cisplatin and Radiation Therapy selenomethionine, placebo, cisplatin - Chemotherapeutic Agent Toxicity, Mucositis | Phase 2 | Terminated | Roswell Park Cancer Institute | 18 | 2009-06-01 | 2014-08-22 |
| Calcium Aluminosilicate Anti-Diarrheal in Treating and Preventing Diarrhea in Patients With Metastatic Colorectal Cancer Receiving Irinotecan calcium aluminosilicate anti-diarrheal, placebo - Chemotherapeutic Agent Toxicity, Colorectal Cancer | Phase 2 | Completed | M.D. Anderson Cancer Center | 100 | 2009-02-04 | 2020-12-02 |
| Acute Pain Caused by Paclitaxel in Patients With Cancer pain questionnaires - Chemotherapeutic Agent Toxicity, Neurotoxicity | Completed | Alliance for Clinical Trials in Oncology | 306 | 2009-02-01 | 2016-07-14 | |
| Cisplatin and Paclitaxel in Treating Patients With Stage IIB, Stage IIC, Stage III, or Stage IV Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cavity Cancer Paclitaxel, Cisplatin - Chemotherapeutic Agent Toxicity, Endometrial Adenocarcinoma | Phase 1 | Completed | Gynecologic Oncology Group | 23 | 2009-02-01 | 2014-12-31 |
| Methotrexate, Glucarpidase, and Leucovorin in Treating Patients With Newly Diagnosed Primary Central Nervous System Lymphoma glucarpidase, leucovorin calcium, methotrexate - Chemotherapeutic Agent Toxicity, Lymphoma | Phase 1 / Phase 2 | Completed | University College, London | 4 | 2008-07-01 | 2014-01-27 |
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Neurotoxicity Syndromes (11) · Breast Neoplasms (8) · Pain (4) · Radiation Injuries (4) · Colonic Neoplasms (3) · Colorectal Neoplasms (3) · Fatigue (3) · Lymphoma (3) · Mucositis (3) · Neutropenia (3) · Peripheral Nervous System Diseases (3) · Rectal Neoplasms (3) · Carcinoma, Non-Small-Cell Lung (2) · Cardiotoxicity (2) · Fallopian Tube Neoplasms (2)
Neoplasms (24) · Neoplasms by Site (19) · Nervous System Diseases (15) · Chemically-Induced Disorders (14) · Pathological Conditions, Signs and Symptoms (13) · Poisoning (11) · Signs and Symptoms (10) · Neoplasms by Histologic Type (9) · Breast Diseases (8) · Skin Diseases (8) · Skin and Connective Tissue Diseases (8) · Digestive System Diseases (7) · Hemic and Lymphatic Diseases (7) · Gastrointestinal Diseases (6) · Wounds and Injuries (6)
Carboplatin (5) · Cisplatin (3) · Paclitaxel (3) · Docetaxel (2) · Filgrastim (2) · Gene Expression Profiling (2) · Leucovorin (2) · Methotrexate (2) · Oxaliplatin (2) · Radiation (2) · Radiotherapy (2) · Taxes (2) · Amifostine (1) · Amplified Fragment Length Polymorphism Analysis (1) · Anvirzel (1)
Alliance for Clinical Trials in Oncology (3) · Centre Francois Baclesse (2) · M.D. Anderson Cancer Center (2) · Northwestern University (2) · University of California, San Francisco (2) · Wake Forest University Health Sciences (2) · Associacao de Investigacao de Cuidados de Suporte em Oncologia (1) · Beth Faiman (1) · Children's Cancer and Leukaemia Group (1) · Dana-Farber Cancer Institute (1) · GERCOR - Multidisciplinary Oncology Cooperative Group (1) · Gynecologic Oncology Group (1) · HealthPartners Institute (1) · Institut Cancerologie de l'Ouest (1) · Institut Claudius Regaud (1)
United States (18) · France (5) · United Kingdom (3) · Austria (1) · Belgium (1) · Chile (1) · Ireland (1) · Israel (1) · New Zealand (1) · Puerto Rico (1) · Turkey (Türkiye) (1)
Charles L. Loprinzi, MD (2) · Hope S. Rugo, MD (2) · Alice Shapiro, PhD (1) · Andrew Wilcock, MD (1) · Antonio Omuro, MD (1) · Anurag Singh (1) · Benoist Chibauldel, MD (1) · Beth Faiman (1) · Brian K. Kee, MD (1) · Bruno Nervi, MD (1) · Carla Taramasco, PhD (1) · Catarina Ribeiro (1) · Charles Loprinzi (1) · Christine Brunner (1) · Christine Chevreau-Dalbianco, MD (1)
PMID 19634161, PMID 21383290, PMID 22415454, PMID 23733756, PMID 24297951, PMID 33337539, PMID 34176021, PMID 38535039
P30CA006516 (1), P30CA036727 (1), U10CA027469 (1), U10CA037404 (1), U10CA037429 (1)