8 completed, 3 unknown, 2 not yet recruiting, 1 recruiting. 9 Not applicable, 3 Phase 2, 3 Phase 3, 1 Early Phase 1, 1 Phase 4.
Follow Chalazion: new trials by email Literature Review of Chalazion trials Research Report on Chalazion
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Omega-3 Supplementation vs Demodex vs Eyelid Cleanser for Pediatric Chalazia Omega-3 supplement, Warm compress, Standard eyelid cleanser - Pediatric Chalazia | Phase 2 | Not yet recruiting | Jaeb Center for Health Research | 168 | 2026-10-01 | 2026-08-25 |
| Is the Use of a Steam Mask an Effective Treatment for Paediatric Chalazion in Comparison to Traditional Warm Compresses? Steam device, Warm Compress - Chalazion | Not applicable | Recruiting | University of Sheffield | 28 | 2026-03-10 | 2026-07-23 |
| Evaluation of Effectiveness and Safety of Intense Pulsed Light Treatment for Chalazion Sham IPL, Active IPL - Chalazion | Not applicable | Not yet recruiting | Lumenis Be Ltd. | 40 | 2026-02-04 | 2026-02-19 |
| Evaluation of Effectiveness and Safety of Intense Pulsed Light Treatment for Chalazion OptiLIGHT - Chalazion | Not applicable | Terminated | Lumenis Be Ltd. | 4 | 2025-09-12 | 2026-01-06 |
| Effect of Different Concentrations of Sevoflurane for Anesthesia Induction in Pediatric Ophthalmic Surgery Sevoflurane - Chalazion | Not applicable | Completed | Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong | 80 | 2025-02-25 | 2026-08-25 |
| Therapeutic Efficacy of Intense Pulsed Light in the Treatment of Chalazion IPL, Conservative treatment or excision with curettage - Chalazion | Not applicable | Unknown | Second Affiliated Hospital, Zhejiang University, School of Medicine | 80 | 2021-08-23 | 2022-09-21 |
| Efficacy of Intense Pulsed Light in the Treatment of Recurrent Chalazia IPL-MGX - Chalazion | Not applicable | Unknown | Second Affiliated Hospital, Zhejiang University, School of Medicine | 35 | 2020-07-01 | 2021-10-07 |
| Probiotics for Chalaziosis Treatment in Children probiotics, conservative treatment - Chalazion | Not applicable | Completed | University of Molise | 26 | 2019-02-01 | 2020-05-05 |
| Probiotics for Treatment of Chalazion in Adults conservative treatment, probiotics - Chalazion | Not applicable | Completed | University of Molise | 20 | 2019-02-01 | 2020-04-14 |
| Safety and Efficacy Study of SUN-131 Transdermal System (TDS) as Compared to Placebo TDS in Patients With a Chalazion SUN-131 1.5% TDS, Placebo TDS - Chalazion | Phase 3 | Completed | Senju USA, Inc. | 263 | 2017-07-31 | 2021-08-05 |
| Safety and Efficacy Study of SUN 131 TDS as Compared to Placebo TDS in Adult Patients With a Chalazion SUN-131 1.5% TDS, Placebo TDS - Chalazion | Phase 2 | Completed | Senju USA, Inc. | 60 | 2014-10-01 | 2017-08-11 |
| Intralesional Tetracycline Injection in the Treatment of Chalazia Tetracycline - Chalazia, Chalazion | Early Phase 1 | Withdrawn | The Cleveland Clinic | 2014-03-01 | 2017-01-12 | |
| Local 5-Fluorouracil Injection for the Treatment of Chalazia: A Prospective, Comparative Study 5-fluorouracil Injection, Triamcinolone Acetonide, Incision and Curettage - Chalazion | Phase 3 | Unknown | University of Washington | 120 | 2013-12-01 | 2020-02-06 |
| Evaluation of Screening Methods for Treatment of Meibomian Gland Dysfunction LipiFlow System - Chalazion, Dry Eye Syndromes | Phase 2 / Phase 3 | Completed | TearScience, Inc. | 50 | 2010-09-01 | 2011-12-06 |
| Treatment of Meibomian Gland Dysfunction and Evaporative Dry Eye Manual Mini System, iHeat Portable Warm Compress Therapy - Chalazion, Dry Eye Syndromes | Not applicable | Completed | TearScience, Inc. | 139 | 2009-02-01 | 2011-12-12 |
| Pediatric Zylet Safety and Efficacy Study loteprednol etabonate/tobramycin opthalmic suspension, vehicle - Chalazion, Hordeolum | Phase 4 | Completed | Bausch & Lomb Incorporated | 108 | 2006-11-01 | 2011-10-07 |
Dry Eye Syndromes (2) · Hordeolum (1) · Meibomian Gland Dysfunction (1) · Pain (1) · Rosacea (1)
Cysts (16) · Eye Diseases (16) · Eyelid Diseases (16) · Neoplasms (16) · Lacrimal Apparatus Diseases (2) · Bacterial Infections (1) · Bacterial Infections and Mycoses (1) · Eye Infections (1) · Eye Infections, Bacterial (1) · Infections (1) · Neurologic Manifestations (1) · Pathological Conditions, Signs and Symptoms (1) · Signs and Symptoms (1) · Skin Diseases (1) · Skin and Connective Tissue Diseases (1)
Conservative Treatment (3) · Curettage (2) · Probiotics (2) · tyramine-deoxysorbitol (2) · Fluorouracil (1) · Loteprednol Etabonate (1) · Sevoflurane (1) · Tetracycline (1) · Triamcinolone (1) · Triamcinolone Acetonide (1)
Lumenis Be Ltd. (2) · Second Affiliated Hospital, Zhejiang University, School of Medicine (2) · Senju USA, Inc. (2) · TearScience, Inc. (2) · University of Molise (2) · Bausch & Lomb Incorporated (1) · Jaeb Center for Health Research (1) · Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong (1) · The Cleveland Clinic (1) · University of Sheffield (1) · University of Washington (1)
United States (9) · China (3) · Italy (2) · United Kingdom (1)
Christy Stevens, OD (2) · Ciro Costagliola, Full Professor (2) · James Chelnis, MD (2) · Amy L Waters, OD, FAAO (1) · Courtney L Kraus, MD (1) · Julian D Perry, M.D. (1) · Laura Periman (1) · Laura Periman, MD (1) · Matthew M Zhang, MD (1) · Timothy L Comstock, OD (1) · Viral Sheth, Phd (1)
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