7 completed, 2 recruiting, 2 terminated, 2 unknown. 5 Not applicable, 3 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Completed 2, Recruiting 1, Terminated 1, Unknown 1 |
| Phase 3 | 3 | Completed 2, Terminated 1 |
| Phase 2 | 1 | Completed 1 |
Follow Central Retinal Artery Occlusion: new trials by email Literature Review of Central Retinal Artery Occlusion trials Research Report on Central Retinal Artery Occlusion
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The GEIR (Grupo español de Ictus Retina) Registry: Rationale and Design of the First Nationwide Multicentre Retinal Stroke Registry in Spain Retinal Artery Occlusion, Central Retinal Artery Occlusion | Not yet recruiting | Germans Trias i Pujol Hospital | 500 | 2027-01-01 | 2026-11-06 | |
| Microneedle Intra-Arterial Injection for Retinal Artery Occlusion Vitrectomy + Direct Intra-Arterial Microneedle Thrombolysis + Standard Care, Standard Clinical Care Only - Central Retinal Artery Occlusion | Not applicable | Recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 24 | 2025-09-01 | 2025-09-03 |
| Visual Involvement in Giant Cell Arteritis Fluorescein and Indocyanine green Angiography, High-resolution Optical Coherence Tomography, Angio-Optical Coherence Tomography - Giant Cell Arteritis, Visual Impairment | Recruiting | ASST Fatebenefratelli Sacco | 762 | 2024-06-27 | 2024-07-15 | |
| A Study of the Efficacy and Safety of KUS121 in Participants With Acute Non-Arteritic Central Retinal Artery Occlusion (CRAO) KUS121 high dose, KUS121 low dose, Sham procedure - Central Retinal Artery Occlusion | Phase 2 | Completed | Kyoto Drug Discovery and Development Co., Ltd. | 17 | 2024-04-16 | 2026-02-18 |
| Effects of HFMH-EMS on Ocular Artery Circulation BOBY, Control - Ocular Surface Disease, Central Retinal Artery Occlusion | Not applicable | Completed | Chung Shan Medical University | 43 | 2023-09-20 | 2025-03-06 |
| Early Reperfusion Therapy With Intravenous Thrombolysis for Recovery of VISION in Acute Central Retinal Artery Occlusion Tenecteplase (until trial protocol V04: Alteplase) - Central Retinal Artery Occlusion | Phase 3 | Terminated | University Hospital Tuebingen | 127 | 2022-10-10 | 2026-05-18 |
| Safety and Efficacy After Selective Intra-arterial Thrombolysis for Central Retinal Artery Occlusion intra-arterial thrombolysis, conservative treatments - Central Retinal Artery Occlusion | Not applicable | Unknown | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | 128 | 2022-06-01 | 2022-09-30 |
| TENecteplase in Central Retinal Artery Occlusion Stuy (TenCRAOS) Intravenous injection of Tenecteplase and one dose of placebo tablet, One tablet of Acetylsalicylic Acid and one dose of IV placebo - Central Retinal Artery Occlusion | Phase 3 | Completed | Oslo University Hospital | 81 | 2020-10-30 | 2025-09-29 |
| Changes of Visual Field Defects After IAT for CRAO selective intra-arterial thrombolysis - Central Retinal Artery Occlusion, Visual Field | Completed | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | 27 | 2020-07-01 | 2023-02-22 | |
| A Phase III Randomized, Blind, Double Dummy, Multicenter Study Assessing the Efficacy and Safety of IV THrombolysis (Alteplase) in Patients With acutE Central retInal Artery Occlusion Alteplase, acetylsalicylic acid, Placebo Oral Tablet - Central Retinal Artery Occlusion | Phase 3 | Completed | Nantes University Hospital | 70 | 2018-06-08 | 2024-01-24 |
| Study of Arterial Recanalization of the Central Retinal Artery Occlusions Central Retinal Artery Occlusion | Completed | Fondation Ophtalmologique Adolphe de Rothschild | 80 | 2016-12-23 | 2022-04-14 | |
| Philadelphia Telemedicine Glaucoma Detection and Follow-Up Study Free Eye Screenings, Enhanced Intervention, Usual Care - Glaucoma, Glaucoma Suspect | Not applicable | Completed | Wills Eye | 906 | 2014-09-01 | 2022-08-22 |
| Retinal Oxygen Saturation, Blood Flow, Vascular Function and High Resolution Morphometric Imaging in the Living Human Eye Branch Retinal Artery Occlusion, Central Retinal Artery Occlusion | Unknown | University of Toronto | 275 | 2012-03-01 | 2013-01-17 | |
| The Effect of Transcorneal Stimulation in Cases of Central Retinal Artery Occlusion Using a New Waveform Transcorneal electric stimulation, Transcorneal stimulation, transcorneal electric stimulation - Central Retinal Artery Occlusion | Not applicable | Terminated | Asociación para Evitar la Ceguera en México | 5 | 2008-04-01 | 2024-05-30 |
Retinal Artery Occlusion (14) · Retinal Vein Occlusion (2) · Vision Disorders (2) · Blindness (1) · Cataract (1) · Diabetic Retinopathy (1) · Giant Cell Arteritis (1) · Glaucoma (1) · Macular Degeneration (1) · Ocular Hypertension (1) · Optic Neuropathy, Ischemic (1)
Arterial Occlusive Diseases (14) · Cardiovascular Diseases (14) · Eye Diseases (14) · Retinal Diseases (14) · Vascular Diseases (14) · Embolism and Thrombosis (2) · Nervous System Diseases (2) · Neurologic Manifestations (2) · Pathological Conditions, Signs and Symptoms (2) · Sensation Disorders (2) · Signs and Symptoms (2) · Thrombosis (2) · Venous Thrombosis (2) · Arteritis (1) · Autoimmune Diseases (1)
Aspirin (2) · Tenecteplase (2) · Conservative Treatment (1) · KUS121 (1) · Standard of Care (1) · Tissue Plasminogen Activator (1) · Vitrectomy (1)
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine (2) · ASST Fatebenefratelli Sacco (1) · Asociación para Evitar la Ceguera en México (1) · Chung Shan Medical University (1) · Fondation Ophtalmologique Adolphe de Rothschild (1) · Germans Trias i Pujol Hospital (1) · Kyoto Drug Discovery and Development Co., Ltd. (1) · Nantes University Hospital (1) · Oslo University Hospital (1) · Second Affiliated Hospital, Zhejiang University, School of Medicine (1) · University Hospital Tuebingen (1) · University of Toronto (1) · Wills Eye (1)
China (3) · France (2) · United States (2) · Belgium (1) · Canada (1) · Denmark (1) · Finland (1) · Germany (1) · Italy (1) · Lithuania (1) · Mexico (1) · Norway (1) · Spain (1) · Sweden (1) · Taiwan (1)
Ping Fei, MD#PhD (2) · Alessandro Invernizzi, Prof. (1) · Chris Hudson, OD, PhD (1) · Julia A Haller, MD (1) · Kunihiro Musashi, MD., Ph.D. (1) · L. J Katz, MD (1) · Lisa A Hark, PhD (1) · Miriam Jessica Lopez-Miranda, MD (1)
PMID 39614619, PMID 28673747, PMID 30770354, PMID 34014814, PMID 38189284, PMID 41109232, PMID 41604638
2018 (1)