3 completed, 3 unknown, 1 terminated. 7 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 7 | Completed 3, Unknown 3, Terminated 1 |
| Phase 2 | 1 | Unknown 1 |
Follow Central Nervous System Protozoal Infections: new trials by email Literature Review of Central Nervous System Protozoal Infections trials Research Report on Central Nervous System Protozoal Infections
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Treating Brain Swelling in Pediatric Cerebral Malaria Mechanical ventilation, Hypertonic saline - Malaria, Cerebral | Phase 3 | Completed | Michigan State University | 57 | 2018-01-08 | 2025-03-17 |
| Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases in Neurological Disorders in DRC Immunochromatographic HAT tests (DSD), Card Agglutination Trypanosoma Test, TB POC Nucleic Acid Amplification Test (Molbio Diagnostics) - Neurological Disorders, Cerebral Malaria | Phase 3 | Completed | Institute of Tropical Medicine, Belgium | 352 | 2012-09-01 | 2016-01-18 |
| Prevention of Congenital Toxoplasmosis With Pyrimethamine + Sulfadiazine Versus Spiramycine During Pregnancy Pyrimethamine/Sulfadiazine, Spiramycine - Congenital Toxoplasmosis | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 149 | 2010-11-01 | 2016-09-29 |
| Assessment of Two Therapeutic Strategies in the Treatment of Children With Congenital Toxoplasmosis reducing treatment to 3 months, registered length of treatment - Congenital Toxoplasmosis | Phase 3 | Terminated | Centre Hospitalier Universitaire Dijon | 302 | 2010-07-28 | 2024-02-22 |
| Randomized Trial of Erythropoietin During Cerebral Malaria Placebo, Erythropoietin - Cerebral Malaria | Phase 2 / Phase 3 | Unknown | Claude Bernard University | 120 | 2007-10-01 | 2008-06-13 |
| Mannitol as Adjunct Therapy for Childhood Cerebral Malaria Mannitol - Cerebral Malaria | Phase 3 | Unknown | Makerere University | 156 | 2004-10-01 | 2005-06-24 |
| Efficacy of Intrarectal Versus Intravenous Quinine for the Treatment of Childhood Cerebral Malaria Intrarectal quinine - Cerebral Malaria | Phase 3 | Unknown | Makerere University | 108 | 2003-09-01 | 2005-08-04 |
Malaria, Cerebral (5) · Malaria (3) · Toxoplasmosis, Congenital (2) · Coma (1) · Meningitis, Bacterial (1) · Meningitis, Cryptococcal (1) · Neglected Diseases (1) · Nervous System Diseases (1) · Neurosyphilis (1) · Tuberculosis, Central Nervous System (1)
Central Nervous System Diseases (7) · Central Nervous System Infections (7) · Central Nervous System Parasitic Infections (7) · Infections (7) · Parasitic Diseases (7) · Protozoan Infections (7) · Nervous System Diseases (6) · Mosquito-Borne Diseases (5) · Vector Borne Diseases (5) · Coccidiosis (2) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Infant, Newborn, Diseases (2) · Malaria (2) · Pathological Conditions, Signs and Symptoms (2)
Erythropoietin (1) · Mannitol (1) · Pyrimethamine (1) · Respiration, Artificial (1) · Saline Solution, Hypertonic (1) · Spiramycin (1) · Sulfadiazine (1) · epoetin beta (1)
Makerere University (2) · Assistance Publique - Hôpitaux de Paris (1) · Centre Hospitalier Universitaire Dijon (1) · Claude Bernard University (1) · Institute of Tropical Medicine, Belgium (1) · Michigan State University (1)
France (2) · Uganda (2) · Democratic Republic of the Congo (1) · Malawi (1) · Mali (1)
Emmanuel Bottieau, MD (1) · Jane Achan, MBChB (1) · Laurent Mandelbrot, MD (1) · Marleen Boelaert, MD, PhD (1) · Terrie E Taylor, DO (1)
PMID 17958887, PMID 19630971, PMID 19852829, PMID 34020114
2009 (1), U01AI126610 (1)