9 completed, 6 unknown, 4 recruiting, 3 terminated. 8 Not applicable, 6 Phase 2, 3 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 8 | Completed 5, Unknown 2, Terminated 1 |
| Phase 2 | 6 | Unknown 2, Completed 1, Recruiting 1, Suspended 1, Terminated 1 |
| Phase 1 | 3 | Unknown 2, Terminated 1 |
| Phase 3 | 1 | Recruiting 1 |
Follow Cancer of Rectum: new trials by email Literature Review of Cancer of Rectum trials Research Report on Cancer of Rectum
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| LIQUID BIOPSY FOCUSING ON CIRCULATING TUMOR CELLS AND CIRCULATING TUMOR DNA AS PRECISION MEDICINE IN GASTROINTESTINAL TUMORS No Interventions - Cancer of Rectum, Cancer of Pancreas | Active not recruiting | Hospital do Coracao | 273 | 2025-01-10 | 2025-04-27 | |
| Association Between the Composition of the Intestinal Microbiota and Tumor Response in Locally Advanced Rectal Cancer Stool collection - Cancer of Rectum | Terminated | Centre Oscar Lambret | 2 | 2024-02-19 | 2026-03-18 | |
| Abdominopelvic Cancer Prehabilitation Prehabilitation - Prehabilitation, Cancer of Colon | Not applicable | Completed | Universitat Jaume I | 66 | 2023-06-01 | 2025-01-29 |
| Immunotherapy in Patients With Early dMMR Rectal Cancer Nivolumab, Ipilimumab - Cancer of Rectum | Phase 2 | Recruiting | Odense University Hospital | 39 | 2023-02-01 | 2025-08-07 |
| Preoperative ChemoRadiation And FOLFOXIRI for Rectal Cancer (CRAFTER) for Rectal Cancer combination of drugs (chemoradiation (capecitabine and radiation) + FOLFOXIRI (Oxaliplatin, leucovorin, irinotecan, and fluorouracil) - Cancer of Rectum | Phase 2 | Suspended | Rutgers, The State University of New Jersey | 38 | 2022-05-13 | 2025-12-04 |
| Developing and Evaluating Product Messaging Control, Warning Labels, Tax - Cancer of Colon, Cancer of Rectum | Not applicable | Completed | University of North Carolina, Chapel Hill | 4160 | 2021-10-18 | 2023-08-18 |
| Clinical Trial Comparing Standard Care Versus Prehabilitation in Patients Undergoing Cancer Surgery Prehabilitation - Cancer of Colon, Cancer of Rectum | Not applicable | Completed | East Lancashire Hospitals NHS Trust | 42 | 2021-07-15 | 2023-09-07 |
| Tempus Priority Study: A Pan-tumor Observational Study Observation - Breast Cancer, Prostate Cancer | Active not recruiting | Tempus AI | 1000 | 2020-10-19 | 2025-05-06 | |
| Standard Dose Versus High Dose of Radiotherapy in Rectal Preservation With Chemo-radiotherapy in Rectal Cancer Patients 50.4 Gy to the tumor and elective volume, 62 Gy to the clinical tumor volume and 50.4 Gy to the elective volume, Capecitabine 825 mg/m2 twice daily on weekdays - Cancer of Rectum | Phase 3 | Recruiting | Vejle Hospital | 162 | 2020-01-20 | 2026-01-08 |
| Colorectal Health Research Champions Colorectal Health Research Champions - Cancer of Colon, Cancer of Rectum | Not applicable | Terminated | Virginia Commonwealth University | 91 | 2020-01-10 | 2024-02-13 |
| Evaluation of cfDNA as a Marker of Response in Rectal Cancer Analysis of cfDNA - Cancer of Rectum | Not applicable | Completed | Hospital Pedro Hispano | 50 | 2019-11-18 | 2023-05-19 |
| Educational Nursing Intervention Among Patients With Colorectal Cancer During Chemotherapy Educational nursing intervention on nutrition intake related chemotherapy induced side-effects' self-care among the patients with colorectal cancer - Patient Empowerment, Patient Activation | Not applicable | Completed | University of Turku | 82 | 2019-10-21 | 2022-05-27 |
| Plan to Thrive: Extending Cancer Survivorship Care Beyond the Clinic Plan to Thrive smartphone application - Cancer, Breast, Cancer of Colon | Completed | Northwestern University | 33 | 2019-08-19 | 2020-09-09 | |
| Survival of Patients With a Reduction in the Number of Lymph Nodes in Rectal Cancer After Neoadjuvant Chemoradiotherapy Survival - Cancer of Rectum, Lymph Node Disease | Unknown | University of Sao Paulo | 250 | 2019-05-20 | 2020-07-02 | |
| The PIONEER Initiative: Precision Insights On N-of-1 Ex Vivo Effectiveness Research Based on Individual Tumor Ownership (Precision Oncology) Cancer, All Types, Cancer of Liver | Unknown | SpeciCare | 1000 | 2019-03-21 | 2020-12-04 | |
| A Study of the Efficacy of Cannabidiol in Patients With Multiple Myeloma, Glioblastoma Multiforme, and GI Malignancies Cannabidiol, Bortezomib, Leucovorin - Cancer of Pancreas, Cancer of Liver | Phase 1 / Phase 2 | Unknown | Leaf Vertical Inc. | 160 | 2019-01-15 | 2018-07-31 |
| Biomarkers for Predicting Neoadjuvant Chemoradio-resistance for Middle-low Advanced Rectal Cancer Rectal Cancer, Cancer of Rectum | Recruiting | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 152 | 2018-05-21 | 2026-08-18 | |
| SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry Clinical Trial Matching - Cancer, Metastatic, Cancer | Recruiting | Massive Bio, Inc. | 50000 | 2018-01-01 | 2025-10-28 | |
| Fluorescence Targeted Pelvic Lymph Node Mapping Indocyanine Green - Cancer of Rectum, Lymph Node Disease | Phase 1 / Phase 2 | Terminated | Oxford University Hospitals NHS Trust | 1 | 2017-08-01 | 2019-08-13 |
| Radiotherapy Assessments During Intervention ANd Treatment (RADIANT) Radiation Therapy, Cancer | Completed | DxTerity Diagnostics | 16 | 2017-04-06 | 2024-08-07 |
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Rectal Neoplasms (25) · Colonic Neoplasms (11) · Pancreatic Neoplasms (6) · Liver Neoplasms (5) · Neoplasms (5) · Stomach Neoplasms (5) · Breast Neoplasms (4) · Esophageal Neoplasms (4) · Kidney Neoplasms (4) · Ovarian Neoplasms (4) · Prostatic Neoplasms (4) · Urinary Bladder Neoplasms (4) · Uterine Cervical Neoplasms (4) · Glioblastoma (3) · Head and Neck Neoplasms (3)
Colorectal Neoplasms (25) · Digestive System Diseases (25) · Digestive System Neoplasms (25) · Gastrointestinal Diseases (25) · Intestinal Diseases (25) · Intestinal Neoplasms (25) · Neoplasms by Site (25) · Rectal Diseases (25) · Gastrointestinal Neoplasms (24) · Neoplasms (20) · Colonic Diseases (11) · Endocrine Gland Neoplasms (7) · Endocrine System Diseases (7) · Pancreatic Diseases (6) · Female Urogenital Diseases (5)
Capecitabine (3) · Fluorouracil (3) · Leucovorin (3) · Oxaliplatin (3) · Chemoradiotherapy (2) · Ipilimumab (2) · Irinotecan (2) · Nivolumab (2) · Preoperative Exercise (2) · Radiation (2) · Bevacizumab (1) · Bortezomib (1) · Cannabidiol (1) · Gemcitabine (1) · Indocyanine Green (1)
Odense University Hospital (2) · Association de Recherche Experimentale et Clinique en Chirurgie Digestive (1) · Centre Oscar Lambret (1) · DxTerity Diagnostics (1) · East Lancashire Hospitals NHS Trust (1) · Hospital Pedro Hispano (1) · Hospital do Coracao (1) · Kwong Wah Hospital (1) · Leaf Vertical Inc. (1) · Massive Bio, Inc. (1) · Northwestern University (1) · Oxford University Hospitals NHS Trust (1) · Rutgers, The State University of New Jersey (1) · SpeciCare (1) · Takayuki Yoshino (1)
United States (10) · Denmark (3) · Brazil (2) · France (2) · United Kingdom (2) · China (1) · Finland (1) · Hong Kong (1) · Japan (1) · Portugal (1) · Puerto Rico (1) · Spain (1)
Chris Cunningham, MD (1) · Chris Gaffney (1) · Helena Leino-Kilpi, PhD (1) · Hyun Kim, M.D. (1) · Joel Lambert (1) · Ken Dixon, MD (1) · Kristiyana Kaneva, MD, MS, MBA (1) · Lars H Jensen, MD, PhD (1) · Lindsay Jaacks, PhD (1) · Lindsey S Taillie, PhD (1) · Line S Tarpgaard, MD, Phd (1) · Ludmilla T.D. Chinen, PhD (1)
PMID 34001462, PMID 34112154, PMID 37473602, PMID 37721952, PMID 38622655, PMID 38834744
K01HL147713 (1)