5 completed, 1 recruiting, 1 terminated. 7 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 7 | Completed 5, Recruiting 1, Terminated 1 |
| Phase 2 | 1 | Completed 1 |
Follow Bronchial Spasm: new trials by email Literature Review of Bronchial Spasm trials Research Report on Bronchial Spasm
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Compare Safety of 4 Weeks Exposure to Propellants Hydrofluoroalkane 1,1-difluoroethane (HFA-152a) and HFA-1,1,1,2-tetrafluoroethane (134a) HFA-152a, HFA-134a - Asthma | Phase 3 | Recruiting | GlaxoSmithKline | 110 | 2026-09-01 | 2026-11-05 |
| A Study to Investigate the Effects of PT027 (Budesonide/Albuterol Sulfate) Metered-dose Inhaler Compared With Placebo on Exercise-Induced Bronchoconstriction in Adult Patients With Asthma Budesonide/albuterol metered-dose inhaler 160/180 μg, Placebo metered-dose inhaler - Asthma, Exercise-Induced | Phase 3 | Completed | AstraZeneca | 64 | 2023-12-22 | 2025-08-27 |
| Study to Assess Bronchospasm Potentially Induced by Next-Generation Propellant vs HFA Propellant in an MDI in Participants With Well/Partially Controlled Asthma HFA MDI, HFO MDI - Asthma | Phase 3 | Completed | AstraZeneca | 52 | 2023-05-02 | 2026-02-06 |
| Ketamine Efficacy for Acute Severe Bronchospasm in ICU: MACANUDO Trial Ketamine, Fentanyl - Critical Illness, Asthma | Phase 2 / Phase 3 | Completed | Hospital Nossa Senhora da Conceicao | 45 | 2015-06-04 | 2024-05-21 |
| Efficacy and Safety Evaluation in Recurrent Wheezing Attacks Biological vaccine - Bronchospasm; Bronchiolitis, Bronchospasm; Bronchitis | Phase 3 | Completed | Inmunotek S.L. | 120 | 2012-10-01 | 2021-11-08 |
| Single-Dose Cross-Over Study of the Effects of Albuterol-HFA in Exercise Induced Bronchoconstriction albuterol (Armstrong Albuterol HFA), Albuterol Sulfate (Provenetil-HFA), Placebo-HFA - Asthma, Bronchospasm | Phase 3 | Terminated | Amphastar Pharmaceuticals, Inc. | 24 | 2008-02-01 | 2013-07-15 |
| Inhaled Albuterol Sulfate For Acute Wheezing Due To Obstructive Airways Disease In Children albuterol sulfate inhalation aerosol - Asthma | Phase 3 | Completed | GlaxoSmithKline | 80 | 2004-09-01 | 2016-09-23 |
Asthma (6) · Asthma, Exercise-Induced (1) · Bronchiolitis (1) · Bronchitis (1) · Critical Illness (1) · Exercise-Induced Allergies (1) · Respiratory Sounds (1)
Bronchial Diseases (7) · Lung Diseases (7) · Lung Diseases, Obstructive (7) · Respiratory Tract Diseases (7) · Hypersensitivity (6) · Hypersensitivity, Immediate (6) · Immune System Diseases (6) · Respiratory Hypersensitivity (6) · Pathological Conditions, Signs and Symptoms (2) · Disease Attributes (1) · Infections (1) · Pathologic Processes (1) · Respiratory Tract Infections (1) · Signs and Symptoms (1) · Signs and Symptoms, Respiratory (1)
Albuterol (1) · Budesonide (1) · Fentanyl (1) · Ketamine (1) · RNA aptamer SUP-A-004 (1) · norflurane (1)
AstraZeneca (2) · GlaxoSmithKline (2) · Amphastar Pharmaceuticals, Inc. (1) · Hospital Nossa Senhora da Conceicao (1) · Inmunotek S.L. (1)
United States (4) · Argentina (1) · Brazil (1) · Canada (1) · Puerto Rico (1) · Russia (1) · Spain (1) · United Kingdom (1)
Allen T Funkhouser, MC (1) · Craig LaForce, MD (1) · David Miller, MD (1) · Jeffrey Tillinghast, MD (1) · Miguel Casanovas, PhD; MD (1)
PMID 10573240, PMID 16055882, PMID 16226443, PMID 22743675, PMID 31613151, PMID 32387408, PMID 33705665, PMID 40551410, PMID 8499054