4 completed, 1 unknown. 5 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 5 | Completed 4, Unknown 1 |
| Phase 2 | 3 | Completed 2, Unknown 1 |
Follow Blepharospasm: new trials by email Literature Review of Blepharospasm trials Research Report on Blepharospasm
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Non-psychoactive Cannabidiol as an Adjunct to Botulinum Toxin in Blepharospasm Cannabidiol Oral Solution [Epidiolex] - Blepharospasm, Blepharospasm, Benign Essential | Phase 2 / Phase 3 | Completed | Silkiss Eye Surgery | 12 | 2020-05-20 | 2021-11-02 |
| Wumeiwan Jiawei Fang Use in Patients With Blepharospasm Wumeiwan Jiawei Fang, botulinum toxin A - Dry Eye Syndromes, Meige Syndrome | Phase 2 / Phase 3 | Unknown | China Academy of Chinese Medical Sciences | 80 | 2018-01-12 | 2022-11-17 |
| Safety and Efficacy of NABOTA in Treatment of Essential Blepharospasm Clostridium Botulinum Toxin Type A - Blepharospasm | Phase 2 / Phase 3 | Completed | Daewoong Pharmaceutical Co. LTD. | 234 | 2016-10-01 | 2019-06-26 |
| IncobotulinumtoxinA (Xeomin) Versus Placebo in the Treatment of Blepharospasm incobotulinumtoxinA (Xeomin), Placebo - Blepharospasm | Phase 3 | Completed | Merz Pharmaceuticals GmbH | 109 | 2006-10-01 | 2013-03-15 |
| Comparison of Korean Botulinum Toxin Type A Versus Botox in the Treatment of Essential Blepharospasm Korean Botulinum toxin type A (KbtxA) and Botox injection - Blepharospasm | Phase 3 | Completed | Pacific Pharmaceuticals | 60 | 2005-10-01 | 2008-05-22 |
Benign essential blepharospasm (1) · Dry Eye Syndromes (1) · Meige Syndrome (1) · Spasm (1)
Eye Diseases (5) · Eyelid Diseases (5) · Basal Ganglia Diseases (1) · Brain Diseases (1) · Central Nervous System Diseases (1) · Dystonic Disorders (1) · Lacrimal Apparatus Diseases (1) · Movement Disorders (1) · Nervous System Diseases (1) · Neurologic Manifestations (1) · Neuromuscular Manifestations (1) · Pathological Conditions, Signs and Symptoms (1) · Signs and Symptoms (1)
Botulinum Toxins, Type A (3) · 26S proteasome non-ATPase regulatory subunit 13 (1) · Cannabidiol (1) · incobotulinumtoxinA (1)
China Academy of Chinese Medical Sciences (1) · Daewoong Pharmaceutical Co. LTD. (1) · Merz Pharmaceuticals GmbH (1) · Pacific Pharmaceuticals (1) · Silkiss Eye Surgery (1)
South Korea (2) · United States (2) · Canada (1) · China (1)
Joseph Jankovic, Prof. (1) · Sang Y Lee, MD, phD (1)