14 completed, 2 terminated, 1 not yet recruiting, 1 recruiting. 7 Not applicable, 7 Phase 2, 2 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 7 | Completed 5, Not yet recruiting 1, Recruiting 1 |
| Phase 2 | 7 | Completed 6, Withdrawn 1 |
| Phase 1 | 2 | Terminated 2 |
| Phase 3 | 1 | Withdrawn 1 |
Follow Atopic Asthma: new trials by email Literature Review of Atopic Asthma trials Research Report on Atopic Asthma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Vibroacoustic Therapy With Oscillating Positive Expiratory Pressure in the Treatment of Nasal Congestion VPAT (Vibratory Positive Pressure Therapeutic Apparatus）, basic medications (antihistamines, mometasone furoate nasal spray, ICS-LABA, OPEP（Oscillating Positive Expiratory Pressure device） - Atopic Rhinitis, Atopic Asthma | Not applicable | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 200 | 2025-08-01 | 2025-08-11 |
| The Epidemiology, Management and Comorbidities in Alopecia Areata in Czech Republic Exposure of interest - Alopecia Areata, Alopecia Totalis | Completed | Faculty Hospital Kralovske Vinohrady | 123 | 2021-10-15 | 2024-12-03 | |
| A Double Masked, Placebo Controlled, Single Center, Randomized Clinical Trial to Assess the Safety and Efficacy of Subjects With Mild Asthma Induced by the Bronchial Allergen Challenge (BAC) ADX-629, Placebo - Atopic Asthma | Phase 2 | Completed | Aldeyra Therapeutics, Inc. | 8 | 2021-01-09 | 2025-02-17 |
| Atopic Diseases & Human Papilloma Virus HPV test results - Human Papilloma Virus, Atopic Asthma | Completed | Adana Numune Training and Research Hospital | 239 | 2019-08-01 | 2020-05-26 | |
| Probiotics and Capsaicin Evoked Coughs BioGaia-DSM17938, Placebo Comparator: Placebo Control - Atopic Asthma | Not applicable | Completed | McMaster University | 15 | 2019-07-16 | 2021-03-26 |
| Restoration of Microbiota in Neonates Maternal microbiota - Atopic Dermatitis, Atopic Asthma | Not applicable | Recruiting | Karolinska Institutet | 300 | 2019-01-01 | 2025-07-01 |
| Characterization of the Inhibitory Effects of Fevipiprant (QAW039) on Activation of Eosinophils and ILC2 Cells by Prostaglandin D2 Metabolites Blood Sampling - Atopic Asthma | Not applicable | Completed | Fraunhofer-Institute of Toxicology and Experimental Medicine | 17 | 2018-08-16 | 2020-06-17 |
| Determination of Accuracy in Measurement of Total Immunoglobulin E Using a Test Device in Atopic Subjects Blood sample, POCT device - Atopic Asthma | Phase 2 | Completed | Novartis Pharmaceuticals | 193 | 2016-03-01 | 2016-11-15 |
| Airway Response to Repeat Allergen Challenge and the Effect of Ibuprofen in Mild Atopic Asthma ibuprofen, Placebo - Atopic Asthma | Not applicable | Completed | University of Saskatchewan | 13 | 2014-12-01 | 2016-04-20 |
| A Phase IIa Repeat Dose AXP1275 vs Placebo Cross-over Trial With Pulmonary Allergen Challenge in Adults With Asthma AXP1275, AXP1275 matching placebo - Atopic Asthma | Phase 2 | Completed | Axikin Pharmaceuticals, Inc. | 21 | 2013-08-01 | 2016-02-05 |
| Kinetics of IgE Memory B Cells, Plasmablasts and Plasma Cells After Whole Lung Allergen Challenge in Mild Asthmatics Bone Marrow Aspiration, Tonsil Biopsy - Atopic Asthma | Not applicable | Completed | Hamilton Health Sciences Corporation | 12 | 2011-11-01 | 2015-03-20 |
| A Study to Evaluate Safety, Tolerability and Pharmacokinetics of ADC3680B in Subjects With Partly Controlled Atopic Asthma ADC3680B oral, Placebo oral - Atopic Asthma | Phase 2 | Completed | Pulmagen Therapeutics | 36 | 2011-09-01 | 2012-02-20 |
| Randomized Controlled Trial of Silymarin in Asthma Oral Silymarin, Oral Silymarin, maintenance dose, Placebo - Atopic Asthma | Phase 2 / Phase 3 | Withdrawn | Vanderbilt University | 2010-09-01 | 2014-02-24 | |
| Effects of Preventive Treatment for Respiratory Syncytial (RS) Virus Infection During Infancy on Later Atopic Asthma in Preterm Infants Atopic Asthma, Recurrent Wheezing | Completed | Tokai University | 343 | 2010-07-01 | 2014-12-08 | |
| Effect of Supplemental Oral Curcumin in Patients With Atopic Asthma CURCUMIN, no intervention other than stopping study - Atopic Asthma | Not applicable | Completed | University of South Florida | 16 | 2009-03-01 | 2010-08-11 |
| Safety and Efficacy Study of Oral Senicapoc on Allergen Challenge in Atopic Asthmatic Subjects senicapoc, Placebo - Atopic Asthma | Phase 2 | Completed | Icagen | 34 | 2008-10-01 | 2011-07-14 |
| The Effect of Inhibition of B7-mediated Costimulation on Allergic Airway Inflammation in Mild Atopic Asthmatics abatacept, Placebo - Atopic Asthma | Phase 2 | Completed | Washington University School of Medicine | 24 | 2008-10-01 | 2014-02-05 |
| Genetics of Asthma - Bronchoscopy Studies Endotoxin - lipopolysaccharide (LPS) - Atopic Asthma, Healthy | Phase 1 | Terminated | John Sundy | 17 | 2007-09-01 | 2013-07-16 |
| Differential Gene Expression in Lung and Peripheral Blood After Inhaled Allergen Challenge House Dust Mite, Diluent - Atopic Asthma, Healthy | Phase 1 | Terminated | John Sundy | 40 | 2006-10-01 | 2013-07-16 |
Asthma (8) · Hypersensitivity (3) · Dermatitis, Atopic (2) · Rhinitis, Allergic, Perennial (2) · Alopecia Areata (1) · Alopecia universalis (1) · Anemia, Pernicious (1) · Arthritis, Rheumatoid (1) · Autoimmune Diseases (1) · COVID-19 (1) · Colitis, Ulcerative (1) · Cough (1) · Crohn Disease (1) · Diabetes Mellitus, Type 1 (1) · Diffuse alopecia (1)
Hypersensitivity, Immediate (11) · Immune System Diseases (11) · Respiratory Tract Diseases (11) · Respiratory Hypersensitivity (10) · Lung Diseases (9) · Bronchial Diseases (8) · Hypersensitivity (8) · Lung Diseases, Obstructive (8) · Nose Diseases (3) · Otorhinolaryngologic Diseases (3) · Pathological Conditions, Signs and Symptoms (3) · Skin Diseases (3) · Skin and Connective Tissue Diseases (3) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Dermatitis (2)
Blood Specimen Collection (2) · ADX-629 (1) · AXP1275 (1) · Abatacept (1) · Antigens, Dermatophagoides (1) · Curcumin (1) · Histamine Antagonists (1) · Ibuprofen (1) · Lipopolysaccharides (1) · Phenol (1) · Silymarin (1) · milk-thistle extract (1) · senicapoc (1)
John Sundy (2) · Adana Numune Training and Research Hospital (1) · Aldeyra Therapeutics, Inc. (1) · Axikin Pharmaceuticals, Inc. (1) · Faculty Hospital Kralovske Vinohrady (1) · Fraunhofer-Institute of Toxicology and Experimental Medicine (1) · Hamilton Health Sciences Corporation (1) · Icagen (1) · Karolinska Institutet (1) · McMaster University (1) · Novartis Pharmaceuticals (1) · Pulmagen Therapeutics (1) · Second Affiliated Hospital, Zhejiang University, School of Medicine (1) · Tokai University (1) · University of Saskatchewan (1)
Canada (5) · United States (5) · United Kingdom (3) · Germany (2) · China (1) · Czechia (1) · Italy (1) · Netherlands (1) · Spain (1) · Sweden (1) · Turkey (Türkiye) (1)
Don Cockcroft, MD (1) · Gail Gauvreau, PhD (1) · Gail M Gauvreau, PhD (1) · Gulsum Uysal (1) · Hiroyuki Mochizuki, M.D., Ph.D., (1) · Huiying Wang (1) · John S Sundy, M.D., PhD (1) · John S Sundy, M.D., PhD. (1) · Jonathan Green, MD (1) · Louis-Philippe Boulet, MD (1) · Mark Fitzgerald, MD (1) · Paul O'Byrne, MD (1) · Tak H Lee, FRCP (1)
PMID 23292882, PMID 27222654, PMID 28152315, PMID 28665197, PMID 34192396