26 completed. 26 Phase 2, 9 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 26 | Completed 26 |
| Phase 3 | 9 | Completed 9 |
Follow Aspergillosis: new trials by email Literature Review of Aspergillosis trials Research Report on Aspergillosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| iMagIng pulmonaRy Aspergillosis Using Gallium-68-dEferoxamine Radiopharmaceutical: gallium-68-deferoxamine ([68Ga]Ga-DFO-B) - Pulmonary Aspergillosis, Chronic Pulmonary Aspergillosis | Phase 2 | Completed | Radboud University Medical Center | 10 | 2025-05-01 | 2026-08-18 |
| An Open-label Safety Study of PC945 (Opelconazole) Prophylaxis or Pre-emptive Therapy Against Pulmonary Aspergillosis in Lung Transplant Recipients (OPERA-S Study) Opelconazole, Standard of Care - Pulmonary Aspergillosis | Phase 2 | Completed | Pulmocide Ltd | 102 | 2021-11-19 | 2026-04-30 |
| Investigating Treatment With Dupilumab in Patients With Allergic Bronchopulmonary Aspergillosis (ABPA) (LIBERTY ABPA AIRED) dupilumab, Placebo - Allergic Bronchopulmonary Aspergillosis | Phase 2 | Completed | Regeneron Pharmaceuticals | 62 | 2020-09-15 | 2025-04-04 |
| A Study Evaluating Vitamin D in Allergic Bronchopulmonary Aspergillosis Complicating Asthma Glucocorticoids, Vitamin D - Allergic Bronchopulmonary Aspergilloses | Phase 2 / Phase 3 | Completed | Post Graduate Institute of Medical Education and Research, Chandigarh | 30 | 2016-12-01 | 2018-08-23 |
| Evaluation of a Therapeutic Strategy Including Nebulised Liposomal Amphotericin B (Ambisome®) in Maintenance Treatment of Allergic Bronchopulmonary Aspergillosis (Cystic Fibrosis Excluded). Liposomal amphotericin B (Ambisome®), placebo - Allergic Bronchopulmonary Aspergillosis | Phase 2 | Completed | Poitiers University Hospital | 174 | 2014-11-19 | 2020-06-09 |
| ATCF (Azole Therapy in Cystic Fibrosis) Itraconazole/voriconazole - Cystic Fibrosis, Aspergillus Infections | Phase 2 | Completed | Rennes University Hospital | 11 | 2014-06-01 | 2023-05-24 |
| A Randomized Trial of Itraconazole in Acute Stages of Allergic Bronchopulmonary Aspergillosis Itraconazole, Glucocorticoids - Allergic Bronchopulmonary Aspergillosis | Phase 2 / Phase 3 | Completed | Post Graduate Institute of Medical Education and Research, Chandigarh | 191 | 2014-05-01 | 2022-10-07 |
| Voriconazole Versus Oral Steroids in Allergic Bronchopulmonary Aspergillosis Prednisolone, Voriconazole - Allergic Bronchopulmonary Aspergillosis | Phase 2 / Phase 3 | Completed | Post Graduate Institute of Medical Education and Research, Chandigarh | 50 | 2013-06-01 | 2017-12-12 |
| A Randomized Controlled Trial of Inhaled Amphotericin B for Maintaining Remission in Allergic Bronchopulmonary Aspergillosis Inhaled budesonide, Inhaled amphotericin - Allergic Bronchopulmonary Aspergillosis | Phase 2 / Phase 3 | Completed | Post Graduate Institute of Medical Education and Research, Chandigarh | 21 | 2013-05-01 | 2015-08-05 |
| Nebulized Amphotericin B Lipid Complex in Invasive Pulmonary Aspergillosis in Paediatric Patients With Acute Leukaemia AMPHOTERICIN B - Invasive Pulmonary Aspergillosis, Lymphoblastic Leukaemia | Phase 2 | Completed | Fundació Sant Joan de Déu | 32 | 2011-10-01 | 2018-03-29 |
| Study Of The Pharmacokinetics And Safety Of Voriconazole In Children 2 To Less Than 15 Years Old Who Are At High Risk For Systemic Fungal Infection Voriconazole - Aspergillosis, Aspergilloma | Phase 2 | Completed | Pfizer | 21 | 2011-09-01 | 2014-05-09 |
| Monotherapy of Itraconazole Versus Prednisolone in Allergic Bronchopulmonary Aspergillosis Glucocorticoids, Itraconazole - Allergic Bronchopulmonary Aspergillosis | Phase 2 / Phase 3 | Completed | Post Graduate Institute of Medical Education and Research, Chandigarh | 100 | 2011-04-01 | 2017-03-16 |
| Pharmacokinetic, Safety and Efficacy of Intermittent Application of Caspofungin for Antifungal Prophylaxis caspofungin - Fungal Infection | Phase 2 | Completed | Werner J. Heinz | 25 | 2011-04-01 | 2014-01-09 |
| A Study of Caspofungin (MK-0991) in Japanese Children and Adolescents With Documented Candida or Aspergillus Infections (MK-0991-074) Caspofungin - Candidiasis, Esophageal, Candidiasis, Invasive | Phase 2 | Completed | Merck Sharp & Dohme LLC | 20 | 2010-07-06 | 2018-08-27 |
| Trial on the Efficacy and Safety of Two Different Glucocorticoid Dose Regimens in Allergic Bronchopulmonary Aspergillosis Glucocorticoids - Allergic Bronchopulmonary Aspergillosis | Phase 2 / Phase 3 | Completed | Post Graduate Institute of Medical Education and Research, Chandigarh | 92 | 2009-04-01 | 2015-02-24 |
| Prophylaxis of Fungal Invasive Infections in Leukemia Caspofungin - Invasive Pulmonary Aspergillosis | Phase 2 | Completed | Northern Italy Leukemia Group | 100 | 2007-01-01 | 2009-09-22 |
| Caspofungin Maximum Tolerated Dose in Patients With Invasive Aspergillosis caspofungin - Invasive Aspergillosis | Phase 2 | Completed | University of Cologne | 46 | 2006-10-01 | 2013-07-31 |
| Voriconazole For Chronic Bronchopulmonary Aspergillosis Voriconazole - Aspergillosis | Phase 2 / Phase 3 | Completed | Pfizer | 48 | 2005-07-01 | 2010-01-20 |
| Documented Candida or Aspergillus Infections in Pediatric Patients (0991-043) caspofungin acetate - Aspergillosis, Candidiasis | Phase 2 | Completed | Merck Sharp & Dohme LLC | 50 | 2004-04-01 | 2017-02-23 |
| MK0991 in Combination With Standard Antifungal Agent(s) for the Treatment of Salvage Invasive Aspergillosis (0991-037) MK0991, caspofungin acetate, Comparator: amphotericin B, Comparator: lipid formulation of amphotericin B and/or azole - Aspergillosis | Phase 2 | Completed | Merck Sharp & Dohme LLC | 55 | 2003-01-01 | 2015-01-13 |
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Aspergillosis, Allergic Bronchopulmonary (9) · Mycoses (6) · Candidiasis (3) · Pulmonary Aspergillosis (3) · Invasive Fungal Infections (2) · Invasive Pulmonary Aspergillosis (2) · Leukemia (2) · Asthma (1) · Candidiasis, Invasive (1) · Cryptococcosis (1) · Cystic Fibrosis (1) · Granulomatous Disease, Chronic (1) · Hematologic Diseases (1) · Leukemia, Myelomonocytic, Acute (1)
Bacterial Infections and Mycoses (26) · Infections (26) · Mycoses (20) · Lung Diseases (14) · Respiratory Tract Diseases (14) · Lung Diseases, Fungal (12) · Immune System Diseases (11) · Respiratory Tract Infections (10) · Hypersensitivity (9) · Hypersensitivity, Immediate (9) · Pulmonary Aspergillosis (9) · Respiratory Hypersensitivity (9) · Hemic and Lymphatic Diseases (4) · Hematologic Diseases (3)
Caspofungin (6) · Itraconazole (5) · Glucocorticoids (4) · Voriconazole (4) · Azoles (2) · Prednisolone (2) · liposomal amphotericin B (2) · Amphotericin B (1) · Anidulafungin (1) · Micafungin (1) · Standard of Care (1) · Steroids (1) · Vitamin D (1) · dupilumab (1)
Post Graduate Institute of Medical Education and Research, Chandigarh (6) · Merck Sharp & Dohme LLC (4) · Pfizer (3) · National Institute of Allergy and Infectious Diseases (NIAID) (2) · Astellas Pharma Inc (1) · Erasmus Medical Center (1) · Fundació Sant Joan de Déu (1) · Northern Italy Leukemia Group (1) · Poitiers University Hospital (1) · Pulmocide Ltd (1) · Radboud University Medical Center (1) · Regeneron Pharmaceuticals (1) · Rennes University Hospital (1) · University of Cologne (1) · Werner J. Heinz (1)
India (6) · France (5) · United States (5) · Germany (4) · Netherlands (3) · United Kingdom (3) · Italy (2) · Japan (2) · Poland (2) · Spain (2) · Austria (1) · Belgium (1) · Bulgaria (1) · Canada (1) · Hungary (1)
Ritesh Agarwal, MD, DM (2) · A Vulto, PhD (1) · Bart JA Rijnders, MD, PhD (1) · Chiara Cattaneo (1) · Giuseppe Rossi, MD (1) · Jan J Cornelissen, MD, PhD (1) · Jean-Pierre Gangneux, MD, PhD (1) · Jesus Estella, PhMD (1) · Lennert Slobbe, MD (1) · M J Becker, PhD (1) · Oliver A. Cornely, MD (1)
PMID 16436724, PMID 16678903, PMID 18983417, PMID 21729932, PMID 21911573, PMID 23335740, PMID 25451051, PMID 25701307, PMID 26585431, PMID 29331473, PMID 30049743, PMID 30561849, PMID 33027187, PMID 33680981, PMID 34764182, PMID 35822920, PMID 36836250, PMID 38387646, PMID 42845221
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