6 recruiting, 5 completed, 4 active not recruiting, 3 unknown. 9 Not applicable, 4 Phase 1, 3 Phase 2.
Follow Appendix Cancer: new trials by email Literature Review of Appendix Cancer trials Research Report on Appendix Cancer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Appendix Cancer PMP Research Foundation Natural History Study/Patient Registry Appendix Cancer, Pseudomyxoma Peritonei | Recruiting | Appendix Cancer Pseudomyxoma Peritonei Research Foundation | 10000 | 2026-02-02 | 2026-08-17 | |
| Target-specific immunoPET Imaging of Digestive System Carcinoma [68Ga]Ga-DOTA-H2D3, [18F]F-RESCA-RB14, [68Ga]Ga-NOTA-T4 - Malignancy, Digestive Cancer | Not applicable | Recruiting | RenJi Hospital | 400 | 2024-12-04 | 2025-12-31 |
| EQUITY GI: A Prospective Study to Enhance Quality, Inclusivity, and Trial Participation in Black Patients With Gastrointestinal Cancer. EQUITY GI - Gastrointestinal Cancer, Colon Cancer | Not applicable | Recruiting | Case Comprehensive Cancer Center | 200 | 2024-12-01 | 2026-09-15 |
| Intraperitoneal LSTA1 in CRS-HIPEC CRS-HIPEC + LSTA1, CRS-HIPEC alone - Colorectal Cancer, Ovarian Carcinoma | Phase 1 | Withdrawn | University of California, San Diego | 2023-11-30 | 2024-08-20 | |
| Individualized Dose Escalation of 5-FU for Gastrointestinal Cancer FOX dose-escalation algorithm - Colorectal Cancer, Esophagus Cancer | Not applicable | Recruiting | Dartmouth-Hitchcock Medical Center | 36 | 2023-07-14 | 2026-06-22 |
| Value of Right-sided Hemicolectomy for Chldren With High-risk Neuroendocrine Tumors of the Appendix Neoplasms, Appendix Cancer | Unknown | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 1000 | 2023-05-01 | 2024-07-30 | |
| Intraperitoneal Aerosolized Nanoliposomal Irinotecan (Nal-IRI) in Peritoneal Carcinomatosis From Gastrointestinal Cancer PIPAC with Nal-IRI - Peritoneal Carcinomatosis, Peritoneal Metastases | Phase 1 | Active not recruiting | University Hospital, Ghent | 45 | 2022-11-21 | 2026-07-13 |
| Genetics of Appendix Cancer Study Genetic profiling, Retrospective tissue procurement - Appendix Cancer, Appendiceal Cancer | Recruiting | Andreana Holowatyj, PhD, MSCI | 700 | 2022-11-11 | 2025-04-18 | |
| Diagnostic Value of Diffusion-weighted Magnetic Resonance in High-risk Colorectal and Appendiceal Neoplasms Whole-body diffusion-weighted magnetic resonance imaging - Peritoneal Carcinomatosis, Peritoneal Metastases | Not applicable | Active not recruiting | Laval University | 30 | 2022-09-01 | 2025-03-20 |
| Perioperative Exercise and Nutritional Optimisation Prehabilitation Before Surgery for Patients With Peritoneal Malignancy Exercise, Nutrition - Peritoneal Malignancy, Ovarian Cancer | Not applicable | Unknown | Dublin City University | 36 | 2022-09-01 | 2024-03-21 |
| Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes PICO G2 4k - Cancer Pain, Visceral Pain | Not applicable | Recruiting | Cedars-Sinai Medical Center | 360 | 2021-10-05 | 2026-02-20 |
| The Registry of Oncology Outcomes Associated With Testing and Treatment Biomarker Testing (L), Systemic Treatment (T), Patient Reported Outcomes (P) - Adenocarcinoma, Adenocystic Carcinoma | Completed | Taproot Health | 167 | 2021-05-05 | 2024-12-18 | |
| Study of CBX-12 in Subjects With Advanced or Metastatic Refractory Solid Tumors CBX-12 - Solid Tumor, Adult, Epithelial Ovarian Cancer | Phase 1 / Phase 2 | Completed | Cybrexa Therapeutics | 69 | 2021-05-03 | 2026-08-20 |
| The Prevalence of Appendiceal Tumours in Periappendicular Abscess Interval appendectomy, Follow-up MRI at 1 year - Appendix Abscess, Appendicitis | Not applicable | Not yet recruiting | Turku University Hospital | 400 | 2020-12-01 | 2020-11-18 |
| Clinical Trial of a Novel Dose Adjustment Algorithm for Preventing Cytopenia-Related Delays During FOLFOX Chemotherapy Algorithm for cytopenia-related delay and dose-reduction of mFOLFOX chemotherapy - Colorectal Cancer, Gastric Cancer | Not applicable | Completed | Dartmouth-Hitchcock Medical Center | 52 | 2020-10-15 | 2025-10-06 |
| Plasma 5hmC Signatures as a Marker of Colorectal / Appendiceal Peritoneal Metastasis prospective single arm biomarker (plasma cell-free DNA hydroxymethylation) study - Colorectal Cancer Stage IV, Colorectal Cancer Metastatic | Active not recruiting | University of Chicago | 55 | 2019-08-26 | 2025-12-03 | |
| LCI-GI-APX-NIN-001: Nintedanib in Metastatic Appendiceal Carcinoma nintedanib - Appendix Cancer | Phase 2 | Terminated | Wake Forest University Health Sciences | 5 | 2017-11-10 | 2022-08-09 |
| Programs To Support You During Chemotherapy Laboratory Biomarker Analysis, Questionnaire Administration, Daily Survey Administration - Depression, Fatigue | Not applicable | Completed | Wake Forest University Health Sciences | 44 | 2016-08-01 | 2022-10-14 |
| Trial of Intraperitoneal (IP) Oxaliplatin in Combination With Intravenous FOLFIRI Oxaliplatin - Colorectal Cancer, Appendix Cancer | Phase 1 | Completed | University of Massachusetts, Worcester | 14 | 2016-07-01 | 2022-05-31 |
| International Registry of Patients Treated With Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) PIPAC - Peritoneum Cancer, Peritoneum Neoplasm | Unknown | Sabine Rhode | 1000 | 2016-01-01 | 2019-10-08 |
Showing 20 of 21. Sign in to see all of them.
Appendiceal Neoplasms (21) · Colorectal Neoplasms (12) · Stomach Neoplasms (9) · Esophageal Neoplasms (8) · Pancreatic Neoplasms (8) · Colonic Neoplasms (6) · Liver Neoplasms (5) · Peritoneal Neoplasms (5) · Rectal Neoplasms (5) · Anus Neoplasms (4) · Bile Duct Neoplasms (4) · Gallbladder Neoplasms (4) · Ovarian Neoplasms (4) · Gastrointestinal Neoplasms (3) · Neoplasms (3)
Cecal Diseases (21) · Cecal Neoplasms (21) · Digestive System Diseases (21) · Gastrointestinal Diseases (21) · Intestinal Diseases (21) · Intestinal Neoplasms (21) · Neoplasms by Site (21) · Digestive System Neoplasms (20) · Gastrointestinal Neoplasms (18) · Neoplasms (18) · Colonic Diseases (16) · Rectal Diseases (16) · Endocrine Gland Neoplasms (10) · Endocrine System Diseases (10) · Neoplasms by Histologic Type (9)
Hyperthermic Intraperitoneal Chemotherapy (3) · Cytoreduction Surgical Procedures (2) · Algorithms (1) · Biological Therapy (1) · DNA Fingerprinting (1) · Drug Therapy (1) · Exercise (1) · Floxuridine (1) · Immunotherapy (1) · Leucovorin (1) · Mitomycin (1) · Molecular Diagnostic Techniques (1) · Nutritional Status (1) · Oxaliplatin (1) · Patient Reported Outcome Measures (1)
Dartmouth-Hitchcock Medical Center (2) · Wake Forest University Health Sciences (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Andreana Holowatyj, PhD, MSCI (1) · Appendix Cancer Pseudomyxoma Peritonei Research Foundation (1) · Case Comprehensive Cancer Center (1) · Cedars-Sinai Medical Center (1) · Cybrexa Therapeutics (1) · Dublin City University (1) · Laval University (1) · Memorial Sloan Kettering Cancer Center (1) · RenJi Hospital (1) · Sabine Rhode (1) · Taproot Health (1) · Turku University Hospital (1)
United States (14) · Belgium (2) · Argentina (1) · Australia (1) · Austria (1) · Canada (1) · China (1) · Denmark (1) · France (1) · Germany (1) · Ireland (1) · Italy (1) · Netherlands (1) · Poland (1) · Russia (1)
Alexandre Brind'Amour, MD (1) · Amit Mahipal, MBBS (1) · Andreana N Holowatyj, PhD, MSCI (1) · Bradley Switzer, MD (1) · Brennan Spiegel, MD, MSHS (1) · Bruce Bissonnette, MD (1) · Deborah Shelton (1) · Dr. Erin P. Ward, MD (1) · Gabriel A Brooks, M.D. (1) · Gabriel A Brooks, MD (1) · Garrett Nash, MD, MPH (1) · Jennifer Johnson, MD, PhD (1) · Jimmy J Hwang, MD (1) · Joel Baumgartner (1) · Jurgen Mulsow, Mr. (1)
PMID 29149611, PMID 30473706, PMID 40172884, PMID 40779182
K01AT008219 (1), P30CA068485 (1), R01CA252211 (1)