25 completed. 25 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 25 | Completed 25 |
| Phase 2 | 4 | Completed 4 |
Follow Anesthesia: new trials by email Literature Review of Anesthesia trials Research Report on Anesthesia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparison of Procedural Sedation in TEE Remimazolam, Propofol - Anesthesia | Phase 1 | Completed | University of Alabama at Birmingham | 105 | 2025-02-25 | 2025-12-22 |
| Neural Correlates of Lidocaine Analgesia Peripheral Nerve Stimulation, Lidocaine IV - Anesthesia, Pain | Phase 1 | Completed | Keith M Vogt | 30 | 2022-11-22 | 2024-12-24 |
| Cardioprotective Effect of Ketamine-dexmeditomidine Versus Fentanyl-midazolam in Open Heart Surgery in Pediatrics Ketamine- dexmedetomidine, Fentanyl- midazolam, Isoflurane - Anesthesia | Phase 1 | Completed | Cairo University | 81 | 2022-04-15 | 2024-02-07 |
| Assessment of the Pharmacodynamic and Pharmacokinetic Interaction of Remimazolam and Remifentanil Remimazolam, Remifentanil - Anesthesia | Phase 1 | Completed | Paion UK Ltd. | 28 | 2021-04-13 | 2023-09-11 |
| Memory & Conditioning Under Anesthesia Dexmedetomidine, Propofol, Fentanyl - Anesthesia, Pain | Phase 1 | Completed | Keith M Vogt | 92 | 2020-07-30 | 2025-04-18 |
| A Study to Evaluate the Differences in Pharmadynamics, Pharmacokinetics, and Safety Between Ciprofol and Propofol Ciprofol, Propofol - Anesthesia | Phase 1 | Completed | Haisco Pharmaceutical Group Co., Ltd. | 18 | 2020-05-26 | 2020-11-20 |
| A Study Evaluating Drug-Drug Interaction (DDI) Between HSK3486 Injectable Emulsion and Voriconazole Tablets HSK3486, voriconazole +HSK3486 - Anesthesia, Sedation | Phase 1 | Completed | Sichuan Haisco Pharmaceutical Group Co., Ltd | 16 | 2019-12-14 | 2020-12-19 |
| A Study Evaluating the Safety and Pharmacokinetics/Pharmacodynamics of HSK3486 HSK3486, Propofol - Anesthesia, Sedation | Phase 1 | Completed | Sichuan Haisco Pharmaceutical Group Co., Ltd | 16 | 2019-01-09 | 2020-01-09 |
| A Study Evaluating the Mass Balance of [14C]HSK3486 Emulsion Injection in Healthy Adults. HSK3486 - Anesthesia, Sedation | Phase 1 | Completed | Sichuan Haisco Pharmaceutical Group Co., Ltd | 6 | 2019-01-06 | 2019-10-28 |
| A Study Evaluating Drug-Drug Interaction (DDI) Between HSK3486 Injectable Emulsion and Rifampin Capsules HSK3486, rifampin , HSK3486 - Anesthesia, Sedation | Phase 1 | Completed | Sichuan Haisco Pharmaceutical Group Co., Ltd | 16 | 2018-12-14 | 2019-08-20 |
| The Effect of Low Dose Intra-operative Ketamine on Closed-loop Controlled General Anesthesia Ketamine Injectable Solution, Placebo - Anesthesia | Phase 1 | Completed | NeuroWave Systems Inc. | 60 | 2018-03-13 | 2019-05-06 |
| Comparison of Two Intravenous Drug Combinations for Ambulatory Oral & Maxillofacial Surgery Midazolam Hydrochloride, Fentanyl, Ketamine - Anesthesia, Tooth Extraction | Phase 1 | Completed | Albert Einstein College of Medicine | 73 | 2016-10-04 | 2026-03-27 |
| A Study Evaluating Safety, Tolerability, and Pharmacokinetics/Pharmacodynamics of Single IV Dose of HSK3486 Injectable Emulsion in Healthy Subjects. HSK3486 - Anesthesia, Sedation | Phase 1 | Completed | Sichuan Haisco Pharmaceutical Group Co., Ltd | 24 | 2016-05-01 | 2020-03-03 |
| Mixture Nitrous Oxide - Oxygen 50-50% in Transrectal Prostate Biopsy Guided by Ultrasound Nitrous Oxide NO, O2 - Anesthesia | Phase 1 / Phase 2 | Completed | Universidade Federal Fluminense | 84 | 2016-04-01 | 2018-05-09 |
| Memory Modulation by Pain During Anesthesia Dexmedetomidine, Midazolam, Peripheral nerve stimulation - Amnesia, Pain | Phase 1 | Completed | University of Pittsburgh | 32 | 2015-11-19 | 2020-07-01 |
| A Study Evaluating Pharmacodynamics, Pharmacokinetics, Safety and Tolerability of HSK3486 Single Bolus Dose Followed With a 30 Minute Constant Infusion in Healthy Male Subjects HSK3486 - Anesthesia, Sedation | Phase 1 | Completed | Sichuan Haisco Pharmaceutical Group Co., Ltd | 13 | 2015-11-10 | 2021-01-29 |
| Renal Function During Pediatric Anesthesia Sevoflurane, propofol - Renal Failure, Anesthesia | Phase 1 | Completed | Uppsala University | 24 | 2015-10-01 | 2020-11-04 |
| Caudal Block vs Local Wound Infiltration for Hernia Repair in Children Bupivacain- Caudal, Bupivacaine- Local - Anesthesia | Phase 1 / Phase 2 | Completed | University Clinic for Anesthesia Reanimation and Intensive Care Mother Theresa | 80 | 2015-09-01 | 2016-01-05 |
| Evaluating the Safety, Pharmacodynamics and Pharmacokinetics of HSK3486 in Healthy Female Subjects. HSK3486, Propofol - Anesthesia, Sedation | Phase 1 | Completed | Sichuan Haisco Pharmaceutical Group Co., Ltd | 25 | 2015-04-22 | 2019-07-31 |
| A Phase Ⅰb Study of Remimazolam Tosylate in Healthy Volunteers Remimazolam Tosylate - Anesthesia | Phase 1 | Completed | Jiangsu HengRui Medicine Co., Ltd. | 8 | 2014-07-23 | 2018-02-23 |
Showing 20 of 25. Sign in to see all of them.
Pain (3) · Amnesia (1) · Renal Insufficiency (1)
Neurologic Manifestations (3) · Pathological Conditions, Signs and Symptoms (3) · Signs and Symptoms (3) · Female Urogenital Diseases (1) · Female Urogenital Diseases and Pregnancy Complications (1) · Kidney Diseases (1) · Male Urogenital Diseases (1) · Memory Disorders (1) · Mental Disorders (1) · Nervous System Diseases (1) · Neurobehavioral Manifestations (1) · Neurocognitive Disorders (1) · Urogenital Diseases (1) · Urologic Diseases (1)
Propofol (9) · HSK3486 (8) · Transcutaneous Electric Nerve Stimulation (3) · Dexmedetomidine (2) · Fentanyl (2) · Ketamine (2) · Lidocaine (2) · Midazolam (2) · Nitrous Oxide (2) · Remifentanil (2) · Sevoflurane (2) · remimazolam (2) · (2-(1R)-1-cyclopropyl)ethyl-6-isopropyl-phenol (1) · 4-methylbenzenesulfonic acid (1) · Anesthesia (1)
Sichuan Haisco Pharmaceutical Group Co., Ltd (8) · Keith M Vogt (2) · Albert Einstein College of Medicine (1) · Cairo University (1) · Haisco Pharmaceutical Group Co., Ltd. (1) · Jiangsu HengRui Medicine Co., Ltd. (1) · NeuroWave Systems Inc. (1) · Paion UK Ltd. (1) · St. Renatus, LLC (1) · Universidade Federal Fluminense (1) · University Clinic for Anesthesia Reanimation and Intensive Care Mother Theresa (1) · University Hospital, Rouen (1) · University of Alabama at Birmingham (1) · University of British Columbia (1) · University of Campinas, Brazil (1)
China (6) · United States (6) · Brazil (2) · Canada (2) · Egypt (1) · France (1) · Netherlands (1) · North Macedonia (1) · Sweden (1)
Keith M Vogt, MD, PhD (3) · Aleksandra Gavrilovska-Brzanov, MD. Msc (1) · Amany H Saleh, MD (1) · Liyan Miao, PhD (1) · Micael Taavo, MD (1) · Patrick R Brain, DDS (1) · Pei Hu (1) · Remco Vellinga, MD (1) · Richard Merchant, MD FRCPC (1) · Simon Whyte, Dr. (1) · Stephen S Gelfman, MD, DDS (1)
PMID 21106282, PMID 32178858, PMID 32415708, PMID 37713021, PMID 39438214, PMID 40067039, PMID 41836529
R35GM146822 (2)