12 recruiting, 8 unknown, 4 completed, 3 active not recruiting. 7 Early Phase 1, 6 Not applicable, 6 Phase 2, 2 Phase 1, 2 Phase 3.
Follow ANCA Associated Vasculitis: new trials by email Literature Review of ANCA Associated Vasculitis trials Research Report on ANCA Associated Vasculitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| CD19/BCMA-Targeted Universal CAR-T Cell Injection for the Treatment of Autoimmune Diseases RD06-05 CAR-T Cell Injection - SLE - Systemic Lupus Erythematosus, Systemic Sclerosis | Early Phase 1 | Not yet recruiting | Nanjing Bioheng Biotech Co., Ltd. | 30 | 2026-09-01 | 2026-07-16 |
| Clinical Study of BCT301 Cell Injection Therapy for Refractory Autoimmune Diseases BCT301 - System Lupus Erythematosus, Systemic Sclerosis (SSc) | Early Phase 1 | Recruiting | Peking University Third Hospital | 10 | 2025-12-11 | 2026-09-23 |
| EACVI Study on Multimodality Cardiovascular Imaging of Inflammatory Cardiovascular Diseases observational study - Myocarditis, ANCA Associated Vasculitis | Recruiting | Assistance Publique - Hôpitaux de Paris | 5000 | 2025-11-19 | 2026-06-05 | |
| Epithelial Dysmetabolism and Renal Fibrosis in ANCA Vasculitis ANCA Associated Vasculitis, Extramembranous Glomerulopathy | Recruiting | Assistance Publique - Hôpitaux de Paris | 146 | 2025-11-03 | 2026-06-30 | |
| A Study of Anti-CD19/BCMA Universal CAR-T Cell Therapy RD06-05 in Patients With Autoimmune Diseases. RD06-05 CART Cell Injection - SLE, LN | Early Phase 1 | Recruiting | Nanjing Bioheng Biotech Co., Ltd. | 96 | 2025-07-24 | 2026-08-03 |
| Anti-CD19 CAR T-Cell Therapy in Refractory Systemic Autoimmune Diseases CAR T cell - Lupus Erythematosus, Systemic, System; Sclerosis | Phase 1 / Phase 2 | Recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 8 | 2024-11-29 | 2025-04-11 |
| Clinical Study on Targeted CD19 or CD19-BCMA CAR-T Therapy for Autoimmune Diseases CD19 or CD19-BCMA CAR-T - SLE (Systemic Lupus), Systemic Sclerosis | Early Phase 1 | Recruiting | Nanjing Bioheng Biotech Co., Ltd. | 20 | 2024-09-14 | 2026-03-06 |
| Clinical Study on Targeted CD19CAR-T Therapy for Autoimmune Diseases RD06-04 CART Cell Injection - Systemic Lupus Erythematosus, Systemic Sclerosis | Early Phase 1 | Suspended | Nanjing Bioheng Biotech Co., Ltd. | 12 | 2024-09-13 | 2026-02-03 |
| A Study of RD06-04 in Patients With Active Autoimmune Diseases RD06-04 cell infusion - SLE, Sclerosis | Early Phase 1 | Withdrawn | Nanjing Bioheng Biotech Co., Ltd. | 2024-08-31 | 2026-02-03 | |
| CARTIMMUNE: Study of Patients With Autoimmune Diseases Receiving KYV-101 KYV-101, Cyclophosphamide, Fludarabine - Idiopathic Inflammatory Myopathies, Diffuse Cutaneous Systemic Sclerosis | Phase 1 | Active not recruiting | David Porter | 24 | 2024-08-05 | 2026-09-21 |
| Study of Therapeutic Efficacy of Anti-CD19 CAR-T Cells in Children With Refractory Refractory AAV anti-CD19-CAR-T cells - ANCA Associated Vasculitis, CAR-T Cell Therapy | Withdrawn | The Children's Hospital of Zhejiang University School of Medicine | 2024-08-01 | 2026-06-16 | ||
| The Safety and Efficacy of Anti-CD19 CAR-T Cells in Patients With Relapsed/Refractory Autoimmune Diseases anti-CD19-CAR-T cells - Systemic Lupus Erythematosus (SLE), Sjogren's Syndrome | Early Phase 1 | Not yet recruiting | First Affiliated Hospital of Wenzhou Medical University | 9 | 2024-05-27 | 2024-05-17 |
| Anti-CD19-CD3E-CAR-T Cells in Relapsed/Refractory Autoimmune Disease Anti-CD19-CD3E-CAR-T cells - Systemic Lupus Erythematosus (SLE), Sjogren's Syndrome | Not applicable | Unknown | Shanghai Changzheng Hospital | 6 | 2024-04-20 | 2024-04-18 |
| Refractory ANCA Associated Vasculitis and Lupus Nephritis Treated With BCMA-targeting CAR-T Cells PRG-1801 （CAR-T against BCMA） - Lupus Nephritis, ANCA Associated Vasculitis | Not applicable | Recruiting | Lingli Dong | 24 | 2024-02-05 | 2024-02-26 |
| Neutrophil Extracellular Traps in Different Forms of Systemic Sclerosis Blood sample - Systemic Sclerosis, Other Connective Tissue Disease | Recruiting | CHU de Reims | 260 | 2023-11-27 | 2024-06-17 | |
| Early-access Avacopan in Real-world ANCA-associated Vasculitis ANCA Associated Vasculitis | Recruiting | Leiden University Medical Center | 100 | 2023-11-01 | 2025-01-27 | |
| A Trial to Evaluate the Efficacy of Pioglitazone to Promote Renal Tolerance in ANCA-associated Vasculitis - RENATO Trial Pioglitazone (ACTOS®), Placebo of Pioglitazone - ANCA Associated Vasculitis, Rapidly Progressive Glomerulonephritis | Phase 3 | Recruiting | Assistance Publique - Hôpitaux de Paris | 126 | 2023-10-24 | 2026-07-01 |
| PR3-AAV Resilient Remission or PRRR Obinutuzumab, Rituximab - Granulomatosis With Polyangiitis, Microscopic Polyangiitis | Phase 2 | Terminated | Mayo Clinic | 6 | 2023-06-30 | 2026-05-06 |
| Efficacy and Safety for Rituximab Combined With Telitacicept in the Treatment of ANCA-associated Vasculitis (TTCAAVREM) Telitacicept, Placebo of Telitacicept - ANCA Associated Vasculitis | Phase 4 | Recruiting | Chinese SLE Treatment And Research Group | 40 | 2023-06-29 | 2023-07-27 |
| ETA and AT1 Antagonism in ANCA-vasculitis (SPARVASC) Sparsentan - ANCA Associated Vasculitis, Cardiovascular Diseases | Phase 2 | Active not recruiting | University of Edinburgh | 32 | 2022-12-08 | 2026-08-26 |
Showing 20 of 35. Sign in to see all of them.
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis (35) · Lupus Erythematosus, Systemic (10) · Myositis (8) · Scleroderma, Systemic (8) · Sjogren's Syndrome (7) · Granulomatosis with Polyangiitis (4) · Antiphospholipid Syndrome (3) · Autoimmune Diseases (3) · Microscopic Polyangiitis (3) · Cardiovascular Diseases (2) · Churg-Strauss Syndrome (2) · Dermatomyositis (2) · Glomerulonephritis, IGA (2) · Kidney Diseases (2) · Lupus Nephritis (2)
Immune System Diseases (35) · Skin Diseases (35) · Skin Diseases, Vascular (35) · Skin and Connective Tissue Diseases (35) · Systemic Vasculitis (35) · Vascular Diseases (35) · Cardiovascular Diseases (33) · Vasculitis (33) · Autoimmune Diseases (32) · Nervous System Diseases (15) · Connective Tissue Diseases (14) · Musculoskeletal Diseases (12) · Neuromuscular Diseases (11) · Muscular Diseases (10) · Arthritis (9)
Rituximab (4) · Blood Specimen Collection (2) · Cyclophosphamide (2) · Prednisolone (2) · Adrenal Cortex Hormones (1) · Antigens, CD19 (1) · Azathioprine (1) · Hydroxychloroquine (1) · Immunotherapy, Adoptive (1) · Leflunomide (1) · Methylprednisolone (1) · Methylprednisolone Hemisuccinate (1) · Observation (1) · Pioglitazone (1) · Prednisone (1)
Nanjing Bioheng Biotech Co., Ltd. (5) · Assistance Publique - Hôpitaux de Paris (3) · Chinese SLE Treatment And Research Group (2) · Leiden University Medical Center (2) · University Hospital, Brest (2) · CHU de Reims (1) · Cambridge University Hospitals NHS Foundation Trust (1) · David Porter (1) · First Affiliated Hospital of Wenzhou Medical University (1) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (1) · Guy's and St Thomas' NHS Foundation Trust (1) · Lingli Dong (1) · Mayo Clinic (1) · Peking University Third Hospital (1) · Professor Lorraine Harper (1)
China (14) · France (8) · United Kingdom (6) · United States (3) · Netherlands (2) · Italy (1)
Alexandre Karras (1) · David D'Cruz (1) · David Jayne (1) · Dimitrios Chanouzas, MBChB, PhD (1) · Huji Xu, Ph.D, MD (1) · Jianhua Mao, PhD (1) · Jing Li, MD (1) · Jing Xue (1) · Ken Smith (1) · LI Sun, Master's (1) · Lindi Jiang, PhD (1) · Lingli Dong, MD (1) · Lorraine Harper, MRCP PhD (1) · Maria Antonietta D'Agostino (1)
PMID 16996579, PMID 25372085, PMID 25916811, PMID 26312852, PMID 27450392, PMID 30102389, PMID 31720749, PMID 33164993, PMID 36130755, PMID 36906660, PMID 37024906, PMID 42321206
2018 (1), P01DK058335 (1)