3 completed, 2 active not recruiting, 1 unknown. 6 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 6 | Completed 3, Active not recruiting 2, Unknown 1 |
Follow Anal Canal Carcinoma: new trials by email Literature Review of Anal Canal Carcinoma trials Research Report on Anal Canal Carcinoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Chemoradiotherapy Combined With or Without PD-1 Blockade in Anal Canal Squamous Carcinoma Patients PD-1 inhibitor, concurrent chemoradiotherapy - Anal Canal Cancer Stage III, Anal Squamous Cell Carcinoma | Phase 3 | Unknown | Sixth Affiliated Hospital, Sun Yat-sen University | 102 | 2022-05-07 | 2022-05-16 |
| EA2176: Phase 3 Clinical Trial of Carboplatin and Paclitaxel +/- Nivolumab in Metastatic Anal Cancer Patients Carboplatin, Nivolumab, Paclitaxel - Anal Basaloid Carcinoma, Anal Canal Cloacogenic Carcinoma | Phase 3 | Active not recruiting | National Cancer Institute (NCI) | 205 | 2020-11-17 | 2026-10-26 |
| Nivolumab After Combined Modality Therapy in Treating Patients With High Risk Stage II-IIIB Anal Cancer Biopsy Procedure, Biospecimen Collection, Colonoscopy - Anal Basaloid Carcinoma, Anal Canal Cloacogenic Carcinoma | Phase 3 | Active not recruiting | National Cancer Institute (NCI) | 344 | 2018-07-05 | 2026-10-26 |
| Radiation Therapy Plus Fluorouracil With or Without Additional Chemotherapy in Treating Patients With Primary Anal Cancer cisplatin, fluorouracil, mitomycin C - Anal Cancer | Phase 3 | Completed | University College London (UCL) Cancer Institute | 600 | 2001-03-01 | 2013-08-26 |
| Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Stage II or Stage III Anal Cancer cisplatin, fluorouracil, neoadjuvant therapy - Anal Cancer | Phase 3 | Completed | UNICANCER | 350 | 1999-01-04 | 2021-02-17 |
| Chemotherapy Plus Radiation Therapy in Treating Patients With Stage II or Stage III Anal Cancer cisplatin, fluorouracil, mitomycin C - Anal Cancer | Phase 3 | Completed | Radiation Therapy Oncology Group | 682 | 1998-10-01 | 2017-01-04 |
Anus Neoplasms (6)
Anus Diseases (6) · Colorectal Neoplasms (6) · Digestive System Diseases (6) · Digestive System Neoplasms (6) · Gastrointestinal Diseases (6) · Gastrointestinal Neoplasms (6) · Intestinal Diseases (6) · Intestinal Neoplasms (6) · Neoplasms (6) · Neoplasms by Site (6) · Rectal Diseases (6) · Rectal Neoplasms (6)
Cisplatin (3) · Fluorouracil (3) · Radiotherapy (3) · Mitomycin (2) · Nivolumab (2) · Biopsy (1) · Carboplatin (1) · Chemoradiotherapy (1) · Colonoscopy (1) · Immune Checkpoint Inhibitors (1) · Magnetic Resonance Spectroscopy (1) · Neoadjuvant Therapy (1) · Observation (1) · Paclitaxel (1) · Phantoms, Imaging (1)
National Cancer Institute (NCI) (2) · Radiation Therapy Oncology Group (1) · Sixth Affiliated Hospital, Sun Yat-sen University (1) · UNICANCER (1) · University College London (UCL) Cancer Institute (1)
United States (3) · Canada (1) · China (1) · France (1) · South Africa (1) · United Kingdom (1)
Al B. Benson, MD, FACP (1) · Cathy Eng (1) · Didier Peiffert, MD (1) · Jaffer A. Ajani, MD (1) · Joel E. Tepper, MD (1) · John S. MacDonald, MD (1) · Lakshmi Rajdev (1) · Michael G. Haddock, MD (1) · Roger D. James, MD (1) · Xiang-bo Wan, PhD (1)
PMID 18191265, PMID 18430910, PMID 19139424, PMID 20354531, PMID 20564111, PMID 20956625, PMID 23150707, PMID 23578724, PMID 24035327, PMID 28453692, PMID 31534737, PMID 4830803, PMID 8874455
U10CA180820 (2)