42 completed, 6 unknown, 4 terminated, 1 recruiting. 54 Phase 1, 12 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 54 | Completed 42, Unknown 6, Terminated 4, Recruiting 1, Withdrawn 1 |
| Phase 2 | 12 | Completed 7, Unknown 2, Recruiting 1, Terminated 1, Withdrawn 1 |
Follow Allergic Rhinitis: new trials by email Literature Review of Allergic Rhinitis trials Research Report on Allergic Rhinitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety and Immunogenicity of Cat-allergen Intralymphatic Immunotherapy in Patients With Cat Allergy With and Without Asthma ALUTARD SQ® Felis domesticus - Allergic Rhinitis, Allergic Asthma | Phase 1 / Phase 2 | Recruiting | University of Zurich | 36 | 2025-08-20 | 2026-03-16 |
| Study on the Safety, Tolerability, and Pharmacokinetics of PA9159 Nasal Spray in Healthy Adult Subjects PA9159 nasal spray solution, 80 μg one day treatment, PA9159 nasal spray solution, 160 μg one day treatment, PA9159 nasal spray solution, 320 μg one day treatment - Allergic Rhinitis | Phase 1 | Completed | Anhui Palo Alto Pharmaceuticals, Inc. | 36 | 2025-03-14 | 2026-01-15 |
| Trial of INI-2004 in Healthy Volunteers and Participants With Allergic Rhinitis. INI-2004, Placebo - Allergic Rhinitis Due to Weed Pollen, Allergic Rhinitis | Phase 1 | Completed | Inimmune Corporation | 68 | 2023-07-04 | 2026-01-16 |
| Nasal Irrigation With Combination of 0.9% NaCl and Binahong Extract (Anredera Cordifolia) 2,5% In Allergic Rhinitis extract Binahong, Isotonic saline nasal irrigation - Allergic Rhinitis, Allergic Rhinitis Due to House Dust Mite | Phase 1 | Unknown | Gadjah Mada University | 80 | 2023-05-06 | 2024-02-28 |
| To Evaluate the Efficacy and Safety of TQC3564 Tablets in the Treatment of Persistent Allergic Rhinitis TQC3564 tablets, Placebo tablets, TQC3564 tablets, montelukast sodium tablets - Allergic Rhinitis | Phase 1 | Terminated | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 12 | 2022-09-14 | 2024-11-26 |
| Clinical Study of Allergic Rhinitis Therapy by Stem Cells Low dose UCMSCs, Moderate dose UCMSCs, High dose UCMSCs - Allergic Rhinitis | Phase 1 | Unknown | Yantai Yuhuangding Hospital | 18 | 2022-06-13 | 2023-03-28 |
| Treatment of Allergic Rhinitis and Chronic Polypous Rhinosinusitis With Olfactory Mucosa-derived Mesenchymal Stem Cells Olfactory mucosa-derived mesenchymal stem cells, Standard treatment of type Allergic Rhinitis according to the clinical protocols, Standard treatment of type Chronic Polypous Rhinosinusitis according to the clinical protocols - Allergic Rhinitis, Rhinosinusitis Chronic | Phase 1 / Phase 2 | Unknown | Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus | 60 | 2022-03-01 | 2022-01-19 |
| Intralymphatic Immunotherapy With Polvac Grass & Rye Allergen Extract Polvac Grass+Rye, Saline 0.9% - Rhinitis, Allergic, Seasonal, Rhinitis; Allergic, With Asthma | Phase 1 / Phase 2 | Completed | University of Zurich | 60 | 2022-02-10 | 2025-05-21 |
| Safety, Tolerability, and Pharmacokinetics of PA9159 Nasal Spray in Healthy Adult Subjects PA9159 nasal spray solution, 10 μg one day treatment, PA9159 nasal spray solution, 20 μg one day treatment, PA9159 nasal spray solution, 40 μg one day treatment - Allergic Rhinitis | Phase 1 | Completed | Anhui Palo Alto Pharmaceuticals, Inc. | 60 | 2021-11-10 | 2022-01-19 |
| A Trial to Learn More About Repeated Monthly Injections of Lu AG09222 in Participants With Allergies to Grass Pollen Lu AG09222, Placebo - Allergic Rhinitis | Phase 1 | Completed | H. Lundbeck A/S | 30 | 2021-11-01 | 2022-10-27 |
| Airway Immune Response to Allergens (Use Lay Language Here) Segmental allergen challenge - Allergic Asthma, Allergy to Cats | Phase 1 | Unknown | JOSALYN CHO | 12 | 2021-10-28 | 2023-08-31 |
| Tolerability and Potential Efficacy of AD17002 in Subjects With Allergic Rhinitis AD17002, Formulation Buffer - Allergic Rhinitis | Phase 1 / Phase 2 | Completed | Advagene Biopharma Co. Ltd. | 48 | 2019-03-26 | 2025-09-16 |
| Follow up Study 5-6 Years After ILIT With 2 Concomitant Allergens, Birch and Grass ALK Alutard 5-grasses and birch, ALK Diluent - Allergic Rhinitis | Phase 1 / Phase 2 | Completed | Lars Olaf Cardell | 34 | 2018-05-15 | 2022-09-21 |
| Study to Assess the Safety, Tolerability, and Preliminary Efficacy of B244 in Healthy Volunteers and Subjects With Seasonal Allergic Rhinitis B244 suspension, Vehicle - Allergic Rhinitis, Allergic Rhinitis Due to Grass Pollen | Phase 1 / Phase 2 | Completed | AOBiome LLC | 71 | 2017-09-19 | 2022-11-25 |
| Study Evaluating Safety of Ragweed Mix Given by Intralymphatic Node Injections Dose Level 1, Dose Level 2, Placebo - Allergic Conjunctivitis, Allergic Rhinitis | Phase 1 | Terminated | Woodmont Pharmaceuticals, Inc. | 2 | 2017-03-30 | 2018-02-26 |
| Intralymphatic Immunotherapy for House Dust Mite, Dog, and Cat Allergy Using Tyrosine S® in Allergic Rhinitis ILIT with extract of causal allergen, ILIT with normal saline, Rescue medication for allergic rhinitis - Allergic Rhinitis | Phase 1 | Completed | Gachon University Gil Medical Center | 32 | 2016-07-01 | 2020-02-11 |
| Innate Neutrophilic Nasal Inflammation in a Pollen Exposure Chamber ragweed pollen - Allergic Rhinitis | Phase 1 | Completed | The University of Texas Medical Branch, Galveston | 29 | 2016-02-29 | 2018-04-12 |
| A Study of Tolerability and Safety of Two New Doses of Grass MATA MPL Grass MATA MPL 10200, Grass MATA MPL 18200, Placebo - Allergic Rhinitis | Phase 1 | Completed | Allergy Therapeutics | 29 | 2015-08-01 | 2017-03-03 |
| Intralymphatic Immunotherapy (ILIT) for House Dust Mite, Cat, and Dog Allergen in Allergic Rhinitis Patients HollisterStier, Normal saline - Allergic Rhinitis | Phase 1 | Terminated | Gachon University Gil Medical Center | 24 | 2014-08-01 | 2016-08-11 |
| A Safety and Immunogenicity Phase IC Study of CryJ2 -DNA-LAMP Plasmid Vaccine for Assessment of Intradermal (ID) Route of Administration Using the Biojector 2000 Device CryJ2-DNA-LAMP plasmid vaccine by intradermal injection, Saline Control - Allergic Rhinitis | Phase 1 | Completed | Immunomic Therapeutics, Inc. | 22 | 2014-06-01 | 2015-03-25 |
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Rhinitis, Allergic (54) · Hypersensitivity (6) · Asthma (4) · Conjunctivitis, Allergic (4) · Rhinitis (4) · Dermatitis, Atopic (2) · Dust Mite Allergy (2) · Rhinitis, Allergic, Seasonal (2) · Nasal Obstruction (1) · Pruritus (1) · Respiratory Tract Infections (1) · Sneezing (1) · Urticaria (1)
Hypersensitivity, Immediate (54) · Immune System Diseases (54) · Nose Diseases (54) · Otorhinolaryngologic Diseases (54) · Respiratory Hypersensitivity (54) · Respiratory Tract Diseases (54) · Rhinitis (50) · Hypersensitivity (48) · Infections (5) · Bronchial Diseases (4) · Conjunctival Diseases (4) · Conjunctivitis (4) · Eye Diseases (4) · Lung Diseases (4) · Lung Diseases, Obstructive (4)
Fluticasone (5) · Saline Solution (4) · Sodium Chloride (4) · AZD8848 (2) · Oxymetazoline (2) · Therapeutics (2) · azelastine (2) · Allergens (1) · Beclomethasone (1) · Blood Specimen Collection (1) · Diphenhydramine (1) · Esketamine (1) · Histamine (1) · Ibuprofen (1) · Injections, Subcutaneous (1)
Gachon University Gil Medical Center (3) · Anergis (2) · Anhui Palo Alto Pharmaceuticals, Inc. (2) · AstraZeneca (2) · Gilead Sciences (2) · MEDA Pharma GmbH & Co. KG (2) · Merck Sharp & Dohme LLC (2) · Pfizer (2) · University of Zurich (2) · AOBiome LLC (1) · Advagene Biopharma Co. Ltd. (1) · Allergy Therapeutics (1) · Amber Patterson (1) · Bryan Martin, DO (1) · Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (1)
United States (17) · China (4) · South Korea (4) · Switzerland (4) · Canada (3) · Germany (3) · Sweden (3) · United Kingdom (3) · Australia (2) · Austria (2) · Hong Kong (1) · Indonesia (1) · Japan (1) · Netherlands (1) · Taiwan (1)
Christine Kolb (2) · Francois Spertini, MD (2) · Friedrich Horak, MD (2) · Sang Min Lee, M.D., Ph.D. (2) · Amber M Patterson, MD (1) · Bambang Rianto, MD OHNS (1) · Bryan Martin, DO (1) · Cathy M Gelotte, PhD (1) · David B Peden, MS/MD (1) · David Fitz-Patrick, MD (1) · Devi K Jhaveri, D.O. (1) · Edward S Schulman, MD (1)
PMID 19001265, PMID 22464647, PMID 19680119, PMID 22726593, PMID 23374268, PMID 24035151, PMID 26706294, PMID 10831441, PMID 11069570, PMID 11297958, PMID 11468003, PMID 15379842, PMID 16553814, PMID 17083353, PMID 20921983, PMID 21725898, PMID 22621776, PMID 23725004, PMID 24105252, PMID 24439076, PMID 24934402, PMID 24986270, PMID 24990880, PMID 26342289, PMID 26843086, PMID 26915677, PMID 27231527, PMID 27253988, PMID 27677865, PMID 28911971, PMID 30391954, PMID 32679209, PMID 33099797, PMID 33647073, PMID 34088322, PMID 34187620, PMID 34429875, PMID 37402024, PMID 6354022, PMID 9764357
2014 (1)