11 completed, 1 not yet recruiting. 9 Phase 2, 3 Phase 1, 2 Not applicable, 1 Phase 3.
By phase and status
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|
Study to Determine Efficacy, Safety, and Tolerability of B244 as a Topical Spray in Subjects With Moderate to Severe Acne Vulgaris
B244, Vehicle - Acne Vulgaris | Phase 2 | Not yet recruiting | AOBiome LLC | 176 | 2026-10-01 | 2026-10-08 |
B244 Topical Spray for the Treatment of Pruritus in Adults With a History of Atopic Dermatitis
B244, Vehicle - Atopic Dermatitis, Pruritus | Phase 2 | Completed | AOBiome LLC | 547 | 2020-06-24 | 2025-01-28 |
A Study of B244 Delivered as a Topical Spray to Assess Safety in Pediatric Subjects With Atopic Dermatitis
Experimental: B244 - Eczema, Atopic Dermatitis | Phase 1 | Completed | AOBiome LLC | 28 | 2018-12-07 | 2024-08-05 |
A Study to Determine Safety and Efficacy of B244 in Subjects With Mild to Moderate Rosacea
B244, Vehicle - Rosacea | Phase 2 | Completed | AOBiome LLC | 140 | 2018-07-02 | 2022-09-16 |
Study to Determine Safety and Efficacy of B244 in Subjects With Episodic Migraine
B244, Vehicle - Migraine | Phase 2 | Completed | AOBiome LLC | 313 | 2018-03-30 | 2022-10-04 |
Study to Determine Safety and Efficacy of B244 in Subjects With Mild to Moderate Atopic Dermatitis
B244, Vehicle - Atopic Dermatitis Eczema | Phase 2 | Completed | AOBiome LLC | 122 | 2018-01-15 | 2022-10-10 |
Study to Assess the Safety, Tolerability, and Preliminary Efficacy of B244 in Healthy Volunteers and Subjects With Seasonal Allergic Rhinitis
B244 suspension, Vehicle - Allergic Rhinitis, Allergic Rhinitis Due to Grass Pollen | Phase 1 / Phase 2 | Completed | AOBiome LLC | 71 | 2017-09-19 | 2022-11-25 |
A Prospective Study of B244 Delivered as a Topical Spray to Determine Safety and Efficacy in Subjects With Elevated Blood Pressure
B244, Vehicle - Prehypertension, Hypertension, Stage I | Phase 2 | Completed | AOBiome LLC | 132 | 2016-11-01 | 2022-09-15 |
Clinical Trial in Subjects With Mild to Moderate Acne Vulgaris
B244, Placebo - Acne Vulgaris | Phase 2 / Phase 3 | Completed | AOBiome LLC | 372 | 2016-08-01 | 2022-09-16 |
Cosmetic Study to Improve the Appearance of Skin Afflicted With Mild to Moderate Atopic Dermatitis.
AO+Mist, Placebo - Atopic Dermatitis Eczema | Not applicable | Completed | AOBiome LLC | 19 | 2016-05-11 | 2017-08-31 |
Cosmetic Study of AO+Mist in Improving the Appearance of Skin Afflicted With Keratosis Pilaris
Placebo, AO+Mist - Keratosis Pilaris | Not applicable | Completed | AOBiome LLC | 26 | 2015-12-04 | 2017-08-09 |
A Double Blind, Placebo-Controlled, Randomized Study in Subjects With Acne Vulgaris
B244, Placebo - Acne Vulgaris | Phase 1 / Phase 2 | Completed | AOBiome LLC | 36 | 2015-08-05 | 2017-04-05 |
Conditions studied
Acne Vulgaris (3) · Dermatitis, Atopic (2) · Burnett Schwartz Berberian syndrome (1) · Eczema (1) · Headache (1) · Hypertension (1) · Migraine Disorders (1) · Prehypertension (1) · Pruritus (1) · Rhinitis, Allergic (1) · Rosacea (1)
Countries
United States (11) · Canada (1)
Top investigators
Judith Ng-Cashin, MD (4) · Spiros Jamas, ScD (3) · Hyun Kim, PhD (2) · Jeffrey Dover, MD (1) · Joel Neutel, MD (1) · Larry Weiss, MD (1) · Noah Craft, MD (1) · Peter Hino, MD (1)
Results publications
PMID 37396805