39 completed. 39 Phase 1, 11 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 39 | Completed 39 |
| Phase 2 | 11 | Completed 11 |
Follow Alcohol Drinking: new trials by email Literature Review of Alcohol Drinking trials Research Report on Alcohol Drinking
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Metabolic Changes Induced by NMN in Healthy Subjects With Acute Binge Drink β-nicotinamide Mononucleotide, Maltodextrin - Binge Drinking, Liver Injury | Phase 1 / Phase 2 | Completed | Zhejiang Chinese Medical University | 22 | 2024-05-01 | 2025-04-10 |
| Metabolic Changes in Healthy Subjects with Acute Binge Drink Vodka, water - Binge Drinking, Liver Injury | Phase 1 | Completed | Zhejiang Chinese Medical University | 40 | 2024-04-27 | 2025-01-22 |
| Non-invasive Vagal Nerve Stimulation in Alcohol Use Disorder Cervical transcutaneous vagus nerve stimulation (active comparator), Cervical transcutaneous vagus nerve stimulation (sham comparator) - Alcohol Use Disorder | Phase 1 | Completed | VA Office of Research and Development | 19 | 2022-05-02 | 2025-07-03 |
| Effect of Sublingual Formulation of Dexmedetomidine HCl (BXCL501) - Alcohol Interaction Study Placebo, Dexmedetomidine (DEX) for sublingual (SL) administration (BXCL501) - 40µg, Dexmedetomidine (DEX) for sublingual (SL) administration (BXCL501) - 80µg - Alcohol Use Disorder (AUD), Post Traumatic Stress Disorder (PTSD) | Phase 1 | Completed | Pharmacotherapies for Alcohol and Substance Use Disorders Alliance | 10 | 2021-11-09 | 2023-10-26 |
| Effects of Ethanol on the Pharmacokinetics of PT-150 (Formerly ORG34517) (PT150 PK Study) PT150, Beverage - Potential Treatment for Alcohol Dependence-Alcohol Interaction | Phase 1 | Completed | Pop Test Oncology LLC | 10 | 2021-11-01 | 2023-12-04 |
| Opioid Modulation and Neural Reward Activation in Healthy Adults Naltrexone, Placebo - Alcohol Drinking, Opioid Use, Unspecified | Phase 1 / Phase 2 | Completed | University of Colorado, Denver | 13 | 2021-05-01 | 2023-11-28 |
| The Behavioral Effects of Opioids and Alcohol Alcohol, Opioid Agonist - Opioid Use, Alcohol Drinking | Phase 1 | Completed | Sharon Walsh | 11 | 2021-03-24 | 2025-11-20 |
| Effect of Acute Alcohol Intoxication on Neural Processes During Decisions to Engage in HIV Risk Behaviors Alcohol beverage, Placebo beverage - Alcohol Consumption | Phase 1 | Completed | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | 20 | 2021-03-18 | 2026-10-26 |
| Strengths-based Linkage to Alcohol Care (SLAC) for Hazardous Drinkers in Primary Care Strengths-based linkage to alcohol care, Usual care - Alcohol-induced Disorders, Alcohol Drinking | Phase 1 | Completed | VA Office of Research and Development | 140 | 2021-01-01 | 2026-01-13 |
| Timing Personalized Feedback After Alcohol Health Education e-checkup to go, Feedback booster - College Student Drinking | Phase 1 / Phase 2 | Completed | Abby Braitman | 195 | 2020-11-30 | 2023-05-03 |
| Neuroimmune Dysfunction in Alcohol Use Disorder Minocycline, Sugar pill - Alcohol Drinking, Alcohol-Related Disorders | Phase 1 | Completed | University of Maryland, Baltimore | 142 | 2020-02-03 | 2023-12-01 |
| Marijuana Effects on Simulated Driving Performance Marijuana, Alcohol, placebo alcohol - Cannabis, Cannabis Use | Phase 1 | Completed | Shanna Babalonis, PhD | 10 | 2019-07-01 | 2024-07-31 |
| The Alcohol-Pain Connection: Mechanisms and Genetic/Psychological Correlates Low Alcohol, Moderate Alcohol, Placebo Alcohol - Pain, Alcohol Drinking | Phase 1 | Completed | Syracuse University | 379 | 2019-05-12 | 2022-08-17 |
| Clinical Trial to Evaluate the Safety of PT150 (Formerly ORG34517) When it is Taken Concurrently With Alcohol PT150, Beverage - Alcohol Dependence, Alcohol Interaction | Phase 1 | Completed | Pop Test Oncology LLC | 10 | 2018-09-01 | 2019-08-22 |
| St. PETERsburg Pain and Alcohol Intervention With Naltrexone and Nalmefene Low dose naltrexone, Nalmefene - HIV Infection, Alcohol Use | Phase 1 / Phase 2 | Completed | Boston Medical Center | 11 | 2018-07-03 | 2020-08-24 |
| Lacosamide Effects on Alcohol Self Administration and Craving in Heavy Drinkers Lacosamide, Placebo oral capsule - Alcohol Use Disorder | Phase 1 | Completed | Boston Medical Center | 66 | 2018-04-15 | 2021-06-03 |
| Personalized Booster Feedback After Alcohol Health Education e-checkup to go, Feedback-only booster, Feedback-plus-personal-contact booster - College Student Drinking | Phase 1 / Phase 2 | Completed | Abby Braitman | 249 | 2018-02-19 | 2022-06-30 |
| Mavoglurant in Alcohol Drinking Mavoglurant, Placebo - Alcohol Drinking | Phase 1 | Completed | Yale University | 34 | 2018-02-07 | 2024-08-06 |
| Reduced Nicotine Cigarettes in Smokers With and Without Alcohol Use Disorder Reduced nicotine cigarettes - Alcohol Drinking, Cigarette Smoking Toxicity | Phase 1 | Completed | Battelle Memorial Institute | 47 | 2017-11-14 | 2021-09-29 |
| Alcohol Health Education With Personalized Feedback Boosters e-checkup to go, Norms-only booster, Norms-plus-Strategies booster - College Student Drinking | Phase 1 / Phase 2 | Completed | Abby Braitman | 528 | 2017-04-11 | 2023-06-22 |
Showing 20 of 39. Sign in to see all of them.
Alcoholism (11) · Alcohol Drinking in College (4) · Alcohol-Related Disorders (4) · Binge Drinking (4) · Drinking Behavior (3) · Alcoholic Intoxication (2) · Fatty Liver (2) · HIV Infections (2) · Pain (2) · Stress Disorders, Post-Traumatic (2) · Substance-Related Disorders (2) · Acute Pain (1) · Alcohol-Induced Disorders (1) · Anxiety Disorders (1)
Behavior (39) · Drinking Behavior (36) · Chemically-Induced Disorders (18) · Mental Disorders (17) · Substance-Related Disorders (17) · Alcohol-Related Disorders (13) · Pathological Conditions, Signs and Symptoms (4) · Neurologic Manifestations (3) · Signs and Symptoms (3) · Behavioral Symptoms (2) · Blood-Borne Infections (2) · Communicable Diseases (2) · Digestive System Diseases (2) · Genital Diseases (2)
Ethanol (11) · Naltrexone (5) · (11R,13S,17S)-11-(1,3-benzodioxol-5-yl)-17-hydroxy-13-methyl-17-prop-1-ynyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta(a)phenanthren-3-one (2) · Beverages (2) · Crisis Intervention (2) · Sugars (2) · Varenicline (2) · Analgesics, Opioid (1) · Baclofen (1) · Behavior Therapy (1) · Dexmedetomidine (1) · Exercise (1) · Immunization, Secondary (1) · Lacosamide (1) · Minocycline (1)
Abby Braitman (4) · Brown University (4) · Yale University (4) · National Institute on Alcohol Abuse and Alcoholism (NIAAA) (3) · Boston Medical Center (2) · Pop Test Oncology LLC (2) · Syracuse University (2) · VA Office of Research and Development (2) · Zhejiang Chinese Medical University (2) · Battelle Memorial Institute (1) · Boston Children's Hospital (1) · Boston University (1) · Northwell Health (1) · Parc de Salut Mar (1) · Pharmacotherapies for Alcohol and Substance Use Disorders Alliance (1)
United States (31) · China (2) · Kenya (2) · Russia (1) · Spain (1)
Abby L Braitman, Ph.D. (4) · Anthony Spirito, Ph.D. (1) · Brian E. Borsari, PhD (1) · Christopher Verrico, PhD (1) · Eric Devine, PhD (1) · Francina Fonseca, MD, PhD (1) · Giao Q. Tran, Ph.D. (1) · Ismene Petrakis, MD (1) · James C Garbutt, M.D. (1) · Jeffrey H. Samet, MD, MA, MPH (1) · Jeffrey Simons, PhD (1) · Jiaomei Li (1) · Jonathan Howland, PhD, MPH (1)
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