12 completed, 9 not yet recruiting, 7 recruiting, 1 enrolling by invitation. 20 Not applicable, 4 Phase 2, 3 Phase 1.
Follow Alcohol: new trials by email Literature Review of Alcohol trials Research Report on Alcohol
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Hybrid Type 1 Randomized Controlled Trial of an Online and Text-Messaging Intervention to Prevent Alcohol and Cannabis Initiation, Escalation, and Consequences Among First-Year College Students Online and Text Message Intervention - Alcohol, Cannabis | Not applicable | Not yet recruiting | The University of Texas at Arlington | 800 | 2028-09-01 | 2026-10-30 |
| Eye-Tracking Alcohol Warning Alcohol Cancer Warning Labels - Alcohol | Not applicable | Not yet recruiting | University of Miami | 50 | 2026-11-01 | 2026-10-20 |
| Impact of GLP-1 Receptor Agonist Therapy on Alcohol Pharmacokinetics Acute Ethanol Dose - GLP-1, Alcohol | Phase 1 | Not yet recruiting | University of Wisconsin, Madison | 5 | 2026-11-01 | 2026-10-29 |
| Flavored Ready-to-Drink Alcohol Restriction in Young Adults: Behavioral and Biomarker Outcomes Flavored Ready-to-Drink alcoholic beverage use restriction - E-cigarette, Alcohol | Not applicable | Not yet recruiting | Medical University of South Carolina | 30 | 2026-10-01 | 2026-09-30 |
| Messages That Motivate: Communicating Alcohol-Related Breast Cancer Risk to Young Adult Women Risk Message, Efficacy Message, Industry Deception - Communication, Message Perception | Not applicable | Not yet recruiting | Ohio State University Comprehensive Cancer Center | 900 | 2026-10-01 | 2026-09-03 |
| Alcohol and Cancer Message Testing Experiment Alcohol health harm message exposure - Alcohol, Message Perception | Not applicable | Not yet recruiting | University of Connecticut | 1400 | 2026-09-01 | 2026-09-30 |
| Designing Effective Alcohol Health Warnings: An Experimental Study With Adults in the U.S. Health warning statement evaluations (bottles), Health warning statement evaluations (ads) - Risk Perceptions, Decision Making | Not applicable | Recruiting | University of Oklahoma | 2000 | 2026-07-27 | 2026-09-10 |
| Prevalence and Associated Factors of High BMI and Periodontitis in Thai Adults Aged Under 60 Years Periodontal Examination, Questionnaire interview, Anthropometric measurements - Diabete Mellitus, Dyslipidaemia | Recruiting | Mahidol University | 93 | 2026-07-01 | 2026-10-19 | |
| Evaluation of a Sexual Violence and Intimate Partner Violence Primary Prevention Program Implemented in Drinking Establishments Safe Night Out Program, No Safe Night Out - Intimate Partner Violence (IPV), Sexual Violence | Not yet recruiting | University of California, San Diego | 650 | 2026-06-01 | 2026-02-27 | |
| Investigating the Effect of Caffeine and Alcohol on Pupil Dynamics Placebo Comparator: Placebo, Caffeine administration, Alcohol (Ethanol) - Caffeine, Alcohol | Not applicable | Recruiting | National University of Singapore | 100 | 2026-06-01 | 2026-06-04 |
| Social Media Psychosocial Support Group in Reducing Alcohol Consumption mHealth-based motivational counselling, Brief alcohol use counselling and health education, Social media group support with engagement management - Alcohol, mHealth Intervention | Not applicable | Recruiting | The University of Hong Kong | 60 | 2026-05-01 | 2026-05-18 |
| Testing Alcohol Cancer Risk Messages Text-only messages, AI-developed Neutral pictorial messages, AI-developed graphic pictorial messages - Alcohol, Cancer | Not applicable | Enrolling by invitation | University of Miami | 850 | 2026-04-21 | 2026-10-20 |
| GLP-1 Receptor Agonists to Decrease Ethanol and CVD Risk in HIV Semaglutide (Rybelsus®), Placebo - HIV, Alcohol | Phase 2 | Recruiting | Vanderbilt University Medical Center | 200 | 2026-04-17 | 2026-05-26 |
| Tirzepatide for Alcohol Use Disorder Tirzepatide, Placebo injections - Alcohol Use Disorder, Obesity and Overweight | Phase 2 | Recruiting | University of Southern California | 42 | 2025-10-06 | 2025-10-14 |
| Piloting a Biomarker-augmented Alcohol Screening, Brief Intervention, and Referral to Treatment (SBIRT) Program Among HIV-affected Adolescents and Young Adults in Zambia Screening, brief intervention, and referral to treatment (SBIRT) - Alcohol | Not applicable | Completed | Centre for Infectious Disease Research in Zambia | 60 | 2025-09-01 | 2026-07-29 |
| Investigating the Effects of Calorie Information and Serving Size of Alcohol Products on Alcohol Consumption. Calorie information manipulation, Serving size manipulation - Obesity and Overweight, Alcohol | Not applicable | Completed | University of Liverpool | 312 | 2025-07-30 | 2026-02-19 |
| A Phase I Study of the Interaction of Alcohol With Oral AFA-281 in Healthy Volunteers AFA-281 is a small molecule, orally available, Alcohol (Ethanol) - Alcohol, Alcohol Use Disorders | Phase 1 | Not yet recruiting | Afasci Inc | 20 | 2025-07-01 | 2024-12-06 |
| Decisions During Drinking Personalized feedback - Alcohol | Not applicable | Completed | University of Washington | 35 | 2025-04-18 | 2026-10-08 |
| Rapid BAC Reduction with Nutraceutical Blend Study Supplement, Placebo - Alcohol Consumption, Alcohol | Phase 2 | Not yet recruiting | Medical Life Care Planners, LLC | 35 | 2024-12-01 | 2024-12-09 |
| Radiofrequency Applications and Alcoholic Neurolysis of Genicular Nerve for the Treatment of Knee Osteoarthritic Pain Radiofrequency, Alcohol 30%, Alcohol 50% - Radiofrequency, Alcohol | Not applicable | Completed | Tanta University | 100 | 2024-07-25 | 2025-01-28 |
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Alcoholism (4) · Marijuana Abuse (3) · Mental Disorders (3) · Neoplasms (3) · Obesity (3) · Overweight (3) · Alcohol Drinking (2) · Behavior, Addictive (2) · Bipolar Disorder (2) · Cigarette Smoking (2) · Psychotic Disorders (2) · Schizophrenia (2) · Smoking (2) · Substance-Related Disorders (2) · Alcoholic Intoxication (1)
Behavior (10) · Chemically-Induced Disorders (7) · Mental Disorders (7) · Alcohol-Related Disorders (5) · Pathological Conditions, Signs and Symptoms (5) · Substance-Related Disorders (5) · Signs and Symptoms (4) · Body Weight (3) · Nutrition Disorders (3) · Nutritional and Metabolic Diseases (3) · Overnutrition (3) · Bipolar and Related Disorders (2) · Cardiovascular Diseases (2) · Compulsive Behavior (2) · Drinking Behavior (2)
Ethanol (9) · Crisis Intervention (1) · Dietary Supplements (1) · Drug Interactions (1) · Mass Screening (1) · Modafinil (1) · Sodium Chloride (1) · Therapeutics (1) · Tirzepatide (1) · semaglutide (1)
University of California, San Francisco (3) · Mclean Hospital (2) · University of Miami (2) · Afasci Inc (1) · Central Institute of Mental Health, Mannheim (1) · Centre Hospitalier Universitaire, Amiens (1) · Centre for Infectious Disease Research in Zambia (1) · Kaiser Permanente (1) · Mahidol University (1) · Medical Life Care Planners, LLC (1) · Medical University of South Carolina (1) · National University of Singapore (1) · Ohio State University Comprehensive Cancer Center (1) · Tanta University (1) · The University of Hong Kong (1)
United States (16) · China (1) · Egypt (1) · France (1) · Germany (1) · Hong Kong (1) · Singapore (1) · Thailand (1) · United Kingdom (1) · Zambia (1)
Taghrid Asfar, MD, MSPH (2) · Brittney Hultgren, PhD (1) · Chen Yu (1) · Darren Mays, MPH, PhD (1) · Glenn-Milo Santos, PhD (1) · Gregory L Smith, MD, MPH (1) · Gregory M Marcus, MD, MAS (1) · Heather Barkholtz, PhD (1) · Hilary A Tindle, MD, MPH (1) · Jamila K. Stockman, PhD, MPH (1) · Jason Euren, MA (1) · Jonathan W Dukes, MD (1) · Julie M McCarthy, PhD (1) · Julie McCarthy, PhD (1) · Kanyawat Rattanasuwan (1)
K23DA050808 (2), K01AA027771 (1), P60AA032176 (1), R01AA022222 (1), R01AA033553 (1), R01CA311193 (1), R21AA031892 (1), R36DA035109 (1), U01CE003735 (1)