6 completed, 2 not yet recruiting. 8 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 8 | Completed 6, Not yet recruiting 2 |
| Phase 2 | 2 | Completed 2 |
Follow Adenophorea Infections: new trials by email Literature Review of Adenophorea Infections trials Research Report on Adenophorea Infections
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of Emodepside in Participants With Soil-transmitted Helminth Infections emodepside (BAY 44-4400), Mebendazole 100 MG, similar placebo to mebendazole - Trichuris Trichiura; Infection, Hookworm Infection | Phase 3 | Not yet recruiting | Swiss Tropical & Public Health Institute | 315 | 2026-11-06 | 2026-08-14 |
| Combination Therapies for Trichuris Trichiura Infection in Schoolchildren in Honduras Placebo, Albendazole 400 mg, Albendazole Plus Ivermectin - Trichuriasis, Strongyloidiasis | Phase 3 | Not yet recruiting | Mundo Sano Foundation | 368 | 2026-11-01 | 2026-06-23 |
| Efficacy and Safety of Emodepside in Participants With Soil-transmitted Helminth Infections emodepside (BAY 44-4400), matching placebo of emodepside, Mebendazole - Trichuris Trichiura; Infection, Hookworm Infection | Phase 3 | Completed | Swiss Tropical & Public Health Institute | 315 | 2025-11-25 | 2026-10-08 |
| Efficacy and Safety of Moxidectin-Albendazole Co-administration in SAC Moxidectin 2 mg Oral Tablet, Albendazole 400 mg Oral Tablet, Placebo Moxidectin - Trichuriasis, Ascariasis | Phase 3 | Completed | Jennifer Keiser | 224 | 2024-05-14 | 2025-09-19 |
| Efficacy of Ivermectin-albendazole vs Albendazole Alone in School-aged Children Infected With Trichuris Trichiura IVM (200 µg/kg) + ALB (400 mg), ALB (400mg) - Trichuriasis | Phase 3 | Completed | Jennifer Keiser | 161 | 2023-10-09 | 2024-04-10 |
| Efficacy and Safety of MOX/ALB Co-administration Moxidectin 2 mg Oral Tablet, Albendazole 400 mg Oral Tablet, Ivermectin 3 mg Oral Tablet - Trichuriasis, Ascariasis | Phase 3 | Completed | Jennifer Keiser | 255 | 2021-06-15 | 2024-01-24 |
| Efficacy and Safety of MOX/ALB vs. IVM/ALB Co-administration moxidectin (8 mg) / albendazole (400 mg), ivermectin (200 µg/kg) / albendazole (400 mg), ALBENDAZOLE 400 Mg ORAL TABLET [ZENTEL] - Trichuriasis, Ascariasis | Phase 2 / Phase 3 | Completed | Jennifer Keiser | 536 | 2021-03-01 | 2024-12-05 |
| Efficacy and Safety of IVM/ALB Co-administration Albendazole, Albendazole and Ivermectin - Trichuriasis | Phase 2 / Phase 3 | Completed | Jennifer Keiser | 1673 | 2018-09-09 | 2024-03-20 |
Trichuriasis (8) · Hookworm Infections (6) · Ancylostomiasis (5) · Ascariasis (4) · Enterobiasis (2) · Helminthiasis (1) · Intestinal Diseases, Parasitic (1) · Strongyloidiasis (1)
Enoplida Infections (8) · Infections (8) · Nematode Infections (8) · Parasitic Diseases (8) · Helminthiasis (7) · Secernentea Infections (6) · Strongylida Infections (6) · Ascaridida Infections (4) · Oxyuriasis (2) · Oxyurida Infections (2) · Digestive System Diseases (1) · Gastrointestinal Diseases (1) · Intestinal Diseases (1) · Rhabditida Infections (1)
Albendazole (6) · Ivermectin (5) · Tablets (3) · moxidectin (3) · Bay 44-4400 (2) · Mebendazole (2) · emodepside (2) · Albumins (1) · Intravital Microscopy (1)
Jennifer Keiser (5) · Swiss Tropical & Public Health Institute (2) · Mundo Sano Foundation (1)
Tanzania (4) · Côte d’Ivoire (2) · Honduras (1) · Laos (1) · Philippines (1) · Uganda (1)
Jennifer Keiser, Professor (2) · Alejandro Javier Krolewiecki, PhD, MD (1) · Gabriela Matamoros, PhD, MSc, BSc (1) · Said Mohammed Ali, MSc (1)
PMID 30885157, PMID 34191812, PMID 34632308, PMID 34856181, PMID 35217670, PMID 36354034, PMID 37357904, PMID 38517907, PMID 39591454, PMID 40675166