4 terminated, 4 unknown, 3 completed, 2 not yet recruiting. 14 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Early Phase 1 | 14 | Terminated 4, Unknown 4, Completed 3, Not yet recruiting 2, Active not recruiting 1 |
Follow Adenoma: new trials by email Literature Review of Adenoma trials Research Report on Adenoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Implantable Microdevices for in Situ Evaluation of Drug Responses in Lung Cancer Implantable Micro- drug delivery Microdevice (IMD) - Lung Cancer, Mesothelioma | Early Phase 1 | Not yet recruiting | Oliver Jonas | 20 | 2026-10-30 | 2026-10-23 |
| An Open-label, Single-arm Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetic Profile, and Preliminary Efficacy of KT032 Cell Injection in Patients With Mesothelin-positive Advanced Solid Tumors. KT032(anti-MSLN chimeric antigen receptor autologous T cell injection) - Ovarian Cancer, Mesothelioma | Early Phase 1 | Not yet recruiting | Weijia Fang, MD | 24 | 2026-03-15 | 2026-02-19 |
| A Safety Study of 212Pb-VMT-alpha-NET in Patients With Neuroendocrine Tumors [212Pb] VMT-α-NET, [203Pb] VMT-α-NET SPECT/CT - Neuroendocrine Tumors, Neuroendocrine Tumor of the Lung | Early Phase 1 | Active not recruiting | David Bushnell | 24 | 2023-11-10 | 2025-11-04 |
| [68Ga]Ga-HBED-CC-exendin-4 and [68Ga]Ga-NOTA-exendin-4 PET/CT Imaging in the Same Group of Insulinoma Patients [68Ga]Ga-HBED-CC-exendin-4, [68Ga]Ga-NOTA-exendin-4 - Insulinoma | Early Phase 1 | Unknown | Peking Union Medical College Hospital | 20 | 2021-10-01 | 2022-10-14 |
| Developing Optimal Parameters for Hyperpolarized Noble Gas and Inert Fluorinated Gas MRI of Lung Disorders HP 3He, HP 129Xe, PFP - Lung Transplant, Lung Resection | Early Phase 1 | Terminated | Thunder Bay Regional Health Research Institute | 10 | 2020-11-10 | 2024-10-15 |
| αPD1-MSLN-CAR T Cells for the Treatment of MSLN-positive Advanced Solid Tumors αPD1-MSLN-CAR T cells - Non-small-cell Lung Cancer, Mesothelioma | Early Phase 1 | Unknown | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 10 | 2020-05-13 | 2020-07-28 |
| Heated Intra-peritoneal Chemotherapy With Doxorubicin and Cisplatin for Abdominal for Pelvic Tumors in Pediatric Patients Cisplatin, Cytoreductive Surgery, Doxorubicin - Malignant Abdominal Neoplasm, Malignant Pelvic Neoplasm | Early Phase 1 | Terminated | Mayo Clinic | 2 | 2019-11-08 | 2025-02-20 |
| Clinical Evaluation of 68Ga-NOTA-MAL-Cys39-exendin-4 Positron Emission Tomography in the Detection of Insulinoma 68Ga-NOTA-MAL-Cys39-exendin-4 - Insulinoma | Early Phase 1 | Unknown | Nanjing First Hospital, Nanjing Medical University | 60 | 2019-05-05 | 2019-12-04 |
| A Single Dose FMT Infusion as an Adjunct to Keytruda for Metastatic Mesothelioma Fecal Microbiota Transplant - Mesothelioma | Early Phase 1 | Completed | ProgenaBiome | 1 | 2018-09-18 | 2019-09-23 |
| 18F-FES PET/CT in Imaging Patients With Desmoid Tumors F-18 16 Alpha-Fluoroestradiol, Positron Emission Tomography, Computed Tomography - Deep Fibromatosis/Desmoid Tumor, Familial Adenomatous Polyposis | Early Phase 1 | Terminated | Vanderbilt-Ingram Cancer Center | 3 | 2015-04-01 | 2019-10-03 |
| Re-directed T Cells for the Treatment (FAP)-Positive Malignant Pleural Mesothelioma Adoptive Transfer of re-directed T cells - Malignant Pleural Mesothelioma | Early Phase 1 | Completed | University of Zurich | 4 | 2015-02-19 | 2019-08-07 |
| 68Ga-NOTA-exendin-4 PET/CT for the Localization of Insulinoma and Diagnosis of Nesidioblastosis 68Ga-NOTA-exendin-4 - Insulinoma, Nesidioblastosis | Early Phase 1 | Unknown | Peking Union Medical College Hospital | 100 | 2014-02-01 | 2015-09-25 |
| Amatuximab for High Mesothelin Cancers Amatuximab (MORab-009) - Carcinoma, Pancreatic Ductal, Mesothelioma | Early Phase 1 | Terminated | National Cancer Institute (NCI) | 7 | 2011-07-12 | 2019-12-17 |
| Effect of High-Legume Diet on Colorectal Cancer Risk LIFE - Inflammation, Prevention and Control | Early Phase 1 | Completed | National Cancer Institute (NCI) | 65 | 2005-08-03 | 2019-12-16 |
Mesothelioma (6) · Carcinoma, Non-Small-Cell Lung (3) · Colonic Neoplasms (3) · Insulinoma (3) · Ovarian Neoplasms (3) · Lung Neoplasms (2) · Mesothelioma, Malignant (2) · Adenoma, Islet Cell (1) · Adenomatous Polyposis Coli (1) · Asbestosis (1) · Asthma (1) · Bronchiectasis (1) · Carcinoma, Pancreatic Ductal (1) · Colorectal Neoplasms (1)
Neoplasms (14) · Neoplasms by Histologic Type (14) · Neoplasms, Glandular and Epithelial (14) · Neoplasms by Site (13) · Digestive System Diseases (10) · Digestive System Neoplasms (9) · Neoplasms, Mesothelial (8) · Endocrine Gland Neoplasms (7) · Endocrine System Diseases (7) · Lung Diseases (6) · Pancreatic Diseases (6) · Respiratory Tract Diseases (6) · Respiratory Tract Neoplasms (6) · Thoracic Neoplasms (6)
Magnetic Resonance Spectroscopy (2) · 1,2-diaminocyclohexaneplatinum II citrate (1) · 68Ga-NOTA-exendin-4 (1) · Cisplatin (1) · Cytoreduction Surgical Procedures (1) · Doxorubicin (1) · Fecal Microbiota Transplantation (1) · Hyperthermic Intraperitoneal Chemotherapy (1) · Platinum (1) · Specimen Handling (1) · Sulfur Hexafluoride (1) · X-Rays (1) · amatuximab (1) · perflutren (1) · sodium thiosulfate (1)
National Cancer Institute (NCI) (2) · Peking Union Medical College Hospital (2) · David Bushnell (1) · Mayo Clinic (1) · Nanjing First Hospital, Nanjing Medical University (1) · Oliver Jonas (1) · ProgenaBiome (1) · Thunder Bay Regional Health Research Institute (1) · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (1) · University of Zurich (1) · Vanderbilt-Ingram Cancer Center (1) · Weijia Fang, MD (1)
United States (6) · China (4) · Canada (1) · Switzerland (1)
Alessandra Curioni, MD (1) · Ashish Patel, MD (1) · David Bushnell, MD (1) · Fang Li, MD (1) · Feng Wang, Ph.D (1) · Matthew R Young, Ph.D. (1) · Mitchell S Albert, PhD (1) · Patricio C. Gargollo, M.D. (1) · Raffit Hassan, M.D. (1) · Raphael Bueno, MD (1) · Xiaorong Dong (1) · Zhaohui Zhu, MD (1)
PMID 35584850, PMID 35762891, PMID 39499011
P30CA068485 (1), R01CA243014 (1), ZIAEB000073 (1)