30 completed, 15 recruiting, 13 unknown, 5 active not recruiting. 45 Not applicable, 4 Phase 2, 2 Phase 3, 1 Phase 4.
Follow Acute Hypoxemic Respiratory Failure: new trials by email Literature Review of Acute Hypoxemic Respiratory Failure trials Research Report on Acute Hypoxemic Respiratory Failure
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Adiposity Distribution in Acute Respiratory Failure PEEP Titration Using Electrical Impedance Tomography (EIT), Body Positioning: Supine and Prone - Acute Hypoxemic Respiratory Failure, Obesity | Not applicable | Not yet recruiting | Maurizio F. Cereda, MD | 80 | 2028-01-01 | 2025-06-13 |
| Protocolized Weaning of High-Flow Nasal Cannula in Adult Patients Protocolized HFNC Weaning Strategy, Usual Care HFNC Weaning - Acute Hypoxemic Respiratory Failure, High-Flow Nasal Cannula Therapy | Not applicable | Not yet recruiting | Rush University Medical Center | 2000 | 2026-11-01 | 2026-09-25 |
| EARLY-SARDS: Early AlveolaR Lung biologY Underling Sepsis-Associated ARDS Serial bronchoalveolar lavage and biological-physiological assessment - Acute Hypoxemic Respiratory Failure, Sepsis | Not yet recruiting | Hospital Universitari Vall d'Hebron Research Institute | 145 | 2026-10-15 | 2026-08-28 | |
| Evaluation of the FreeO2 System for Oxygen Weaning After Acute Hypoxemic Respiratory Failure FreeO2 automated oxygen titration system, Standard oxygen weaning - Acute Hypoxemic Respiratory Failure, Hypoxemia | Not applicable | Not yet recruiting | Centre Hospitalier Universitaire de Besancon | 40 | 2026-09-15 | 2026-08-31 |
| Spontaneous vs Controlled Mechanical Ventilation in Acute Hypoxemic Respiratory Failure Spontaneous Ventilation Strategy, Controlled Ventilation Strategy - Acute Respiratory Distress Syndrome (ARDS), Acute Hypoxemic Respiratory Failure | Not applicable | Recruiting | Oslo University Hospital | 80 | 2026-09-01 | 2026-10-15 |
| Is Hypoxemia Driving Outcome in Acute Hypoxemic Respiratory Failure? (HOMELAND Study) mediation analysis - Acute Hypoxemic Respiratory Failure | Active not recruiting | Jesus Villar | 1241 | 2026-07-13 | 2026-07-17 | |
| Predicting High-Flow Nasal Cannula Failure in Acute Hypoxemic Respiratory Failure Using Metabolomics and Clinical Data Acute Hypoxemic Respiratory Failure | Recruiting | Hospital del Mar Research Institute (IMIM) | 300 | 2026-06-04 | 2026-06-08 | |
| Bag CPAP vs Standard Oxygen Therapy in Acute Hypoxemic Respiratory Failure Bag CPAP, Standard oxygen - Acute Hypoxemic Respiratory Failure | Not applicable | Not yet recruiting | Prof RWABIHAMA Jean Paul | 250 | 2026-04-20 | 2026-03-19 |
| IntHyx : Intubation Strategies for Patients With Acute Hypoxemic Respiratory Failure Restrictive intubation strategy, Liberal intubation strategy - Acute Hypoxemic Respiratory Failure | Not applicable | Recruiting | University Hospital, Angers | 200 | 2025-12-13 | 2026-08-07 |
| Association Between EIT and CT During PEEP Titration in Patients With Acute Respiratory Failure Acute Hypoxemic Respiratory Failure, Ventilation, Mechanical | Recruiting | Istituto Clinico Humanitas | 30 | 2025-11-01 | 2026-05-19 | |
| Interleukin-6 Guided Treatment With Dexamethasone or Tocilizumab in Patients Hospitalized With Acute Respiratory Symptoms - a Feasibility Study Tocilizumab (Actemra®), Dexamethasone - Acute Hypoxemic Respiratory Failure | Phase 2 | Recruiting | Lorenzo delSorbo | 60 | 2025-10-20 | 2026-10-09 |
| Targeting prEssure-Muscle-index to Avoid Ventilatory Over-Assistance During Pressure Support Ventilation Variation of Pressure Support Levels - Acute Hypoxemic Respiratory Failure, Mechanical Ventilation Complication | Not applicable | Recruiting | Centre for Medical Sciences | 36 | 2025-10-08 | 2026-06-05 |
| PEEP-induced Effects on Respiratory dRivE and EFfort PEEP level changes - ARDS (Moderate or Severe), Acute Hypoxemic Respiratory Failure | Not applicable | Recruiting | Radboud University Medical Center | 20 | 2025-09-02 | 2025-11-17 |
| Safety and Efficacy of Low-Flow ECMO in a Multi-modal Cohort of Adults in Respiratory Failure Low-flow ECMO - Acute Hypoxemic Respiratory Failure, Mechanical Ventilation | Not applicable | Enrolling by invitation | Institute for Extracorporeal Life Support | 30 | 2025-05-01 | 2025-04-22 |
| Awake Prone Positioning in Spontaneous Breathing Patients With Acute Hypoxic Respiratory Failure Due to Pneumonia Awake Prone Positioning - Acute Hypoxemic Respiratory Failure | Not applicable | Recruiting | Universitätsklinikum Hamburg-Eppendorf | 342 | 2025-04-11 | 2026-05-04 |
| Evaluation of Physical Capacity and Energy Requirements in Patients With Hypoxemic Acute Respiratory Failure Acute Hypoxemic Respiratory Failure, Non Invasive Ventilation (NIV) | Active not recruiting | Hospital Universitari de Bellvitge | 500 | 2025-03-01 | 2026-01-16 | |
| Prediction of Duration of Mechanical Ventilation in Acute Hypoxemic Respiratoty Failure Machine learning and logistic regression for the training/testing cohort and validation cohort - Acute Hypoxemic Respiratory Failure | Completed | Jesus Villar | 1241 | 2025-02-02 | 2026-07-08 | |
| Effects of Face Mask Continuous Positive Airway Pressure Vs. Noninvasive Ventilation Vs. High-flow Nasal Oxygen on Intubation-free Survival in Acute Hypoxemic Respiratory Failure: the TRIPOD Randomized Clinical Trial Continuous Positive Airway Pressure, High-flow nasal oxygen, Non-invasive ventilation - Acute Hypoxemic Respiratory Failure, High-Flow Nasal Oxygen Therapy | Not applicable | Recruiting | Southeast University, China | 1300 | 2025-01-23 | 2025-02-26 |
| EIT-Guided Ventilator Settings in AHRF Electrical Impedance Tomography (EIT), Enlight 2100 - Acute Hypoxemic Respiratory Failure, Acute Respiratory Distress Syndrome (ARDS) | Not applicable | Recruiting | Mahidol University | 17 | 2024-12-17 | 2025-04-27 |
| Pressure Muscle Index and Threshold of Over-assistance During Pressure Support Ventilation Measuring Respiratory Mechanics, Randomized Pressure Support - Acute Hypoxemic Respiratory Failure | Unknown | Unity Health Toronto | 20 | 2024-10-04 | 2025-05-20 |
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