4 completed, 4 unknown, 3 not yet recruiting, 3 recruiting. 18 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 18 | Completed 4, Unknown 4, Not yet recruiting 3, Recruiting 3, Active not recruiting 2, Terminated 2 |
Follow Acute Exacerbation of COPD: new trials by email Literature Review of Acute Exacerbation of COPD trials Research Report on Acute Exacerbation of COPD
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Remote Intervention Versus Routine Monitoring in COPD Patients With Chronic Hypercapnia Receiving Home Non-invasive Respiratory Support Remote Management, Remote Monitoring Only - COPD (Chronic Obstructive Pulmonary Disease), Acute Exacerbation of COPD | Not applicable | Not yet recruiting | Sir Run Run Shaw Hospital | 236 | 2027-08-01 | 2026-08-06 |
| Evaluating Customized Antibiotic Duration (CDA) Strategy in Acute Exacerbations of COPD 7-day antibiotic course, 14-day antibiotic course - COPD, Acute Exacerbation of COPD | Not applicable | Not yet recruiting | Capital Development Authority (CDA) | 560 | 2026-10-26 | 2026-10-07 |
| The Impact of Indoor Environmental Quality on Symptoms in Patients With Chronic Obstructive Pulmonary Disease Wearable mobile device, Indoor environmental quality sensor, CAT Questionnaire - COPD (Chronic Obstructive Pulmonary Disease), Acute Exacerbation of COPD | Not applicable | Not yet recruiting | Ziekenhuis Oost-Limburg | 15 | 2026-10-01 | 2026-09-02 |
| Controlled Versus Standard Oxygen Therapy in ICU Patients With Acute Exacerbation of COPD Controlled oxygen therapy, Standard oxygen therapy - Chronic Obstructive Pulmonary Disease (COPD), Acute Exacerbation of COPD | Not applicable | Recruiting | Hôpital Universitaire Taher Sfar | 240 | 2026-01-01 | 2026-09-25 |
| Inhaler Trainer Efficacy Study Inhaler Trainer System, Initial Inhaler Use Assessment, Inhaler Use Instruction - Asthma, Copd | Not applicable | Completed | Koronis Biomedical Technologies | 10 | 2025-10-09 | 2026-06-08 |
| Remote Monitoring of COPD Patients Experiencing an Acute Exacerbation Through Health Evaluations Using Wearable Mobile Technology Wearable mobile device, CAT Questionnaire, DHRQ Questionnaire - Chronic Obstructive Pulmonary Disease (COPD), Acute Exacerbation of COPD | Not applicable | Active not recruiting | David Ruttens | 50 | 2025-03-01 | 2026-09-18 |
| High Flow Nasal Oxygen for Exacerbation COPD HFNO, NIV - Acute Exacerbation of COPD | Not applicable | Recruiting | Franciscus Gasthuis | 40 | 2024-05-14 | 2025-08-21 |
| Randomized Controlled Study of Programmed Weaning From NIV for AECOPD Programmed Weaning From Noninvasive Mechanical Ventilation - Acute Exacerbation of COPD | Not applicable | Active not recruiting | Peking University Third Hospital | 80 | 2023-05-12 | 2026-06-11 |
| Use of MULTIplex PCR, Procalcitonin, and Sputum Appearance to Reduce Duration of Antibiotic Therapy During Severe COPD EXAcerbation: A Controlled, Randomized, Open-label, Parallel-Group, Multicenter Trial Personalized antibiotic treatment, Usual antibiotic treatment - Acute Exacerbation of COPD | Not applicable | Recruiting | Assistance Publique - Hôpitaux de Paris | 204 | 2022-12-08 | 2025-06-25 |
| Antibiotic Stewardship in AECOPD Through CRP-Guided Management The intervention (CRP-guided) group - Acute Exacerbation of COPD, Lung Diseases | Not applicable | Unknown | The University of Hong Kong | 1184 | 2022-09-01 | 2022-05-23 |
| Effects of Chair-Based Exercise Training on Exercise Capacity in Patients With Acute Exacerbation of COPD Treatment group, Chair-Based Exercise Training, Control group, Breathing exercise - Acute Exacerbation of COPD | Not applicable | Completed | Necmettin Erbakan University | 30 | 2022-08-20 | 2024-02-07 |
| Functional Strength Training and Neuromuscular Electrical Stimulation in Severe Acute Exacerbations of COPD Functional strength training, NMES, Daily medical treatment (e.g., oxygen, medrol, duovent, azitromycine) - Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Acute Exacerbation of COPD | Not applicable | Terminated | Hasselt University | 35 | 2022-06-01 | 2025-09-15 |
| High VS Low Flow Nasal O2 for Acute Hypercapnic Respiratory Failure High flow nasal therapy, Low flow oxygen - Acute Hypercapnic Respiratory Failure, Acute Exacerbation of COPD | Not applicable | Unknown | Belfast Health and Social Care Trust | 82 | 2021-06-13 | 2022-04-21 |
| Negative Pressure Ventilation-rehabilitation on Acute Exacerbation of Chronic Obstructive Pulmonary Disease cuirass ventilator (cuirass diameter 21 cm or 34 cm, Dima Italia Srl.,Bologna, Italy), breathing training, and an educational program (relaxation techniques and a home pacing walking exercise) - Chronic Obstructive Pulmonary Disease, Acute Exacerbation of COPD | Not applicable | Unknown | Chang Gung Memorial Hospital | 150 | 2021-04-08 | 2021-04-13 |
| ecco2R to facilitatE earLy libEration From mechanicAl Ventilation inpatientS With Copd Acute Exacerbation Low flow ECCO2R, Invasive mechanical ventilation - Acute Exacerbation of COPD | Not applicable | Unknown | Hospital Quiron Sagrado Corazon | 90 | 2021-02-01 | 2020-08-20 |
| Effect of Blood Flow Restriction Resistance Exercises in COPDAE In-patient Rehabilitation Blood flow restriction resistance exercise - Chronic Obstructive Pulmonary Disease, Acute Exacerbation of COPD | Not applicable | Completed | Hospital Authority, Hong Kong | 53 | 2020-06-10 | 2024-06-17 |
| Non Invasive Ventilation With NAVA vs ASV for AECOPD Non invasive ventilation - Acute Exacerbation of COPD | Not applicable | Completed | Post Graduate Institute of Medical Education and Research, Chandigarh | 76 | 2019-12-01 | 2021-08-09 |
| Extracorporeal CO2 Removal With the Hemolung RAS for Mechanical Ventilation Avoidance During Acute Exacerbation of COPD Hemolung Respiratory Assist System, Invasive mechanical ventilation - Acute Exacerbation of COPD | Not applicable | Terminated | Alung Technologies | 113 | 2018-02-18 | 2022-10-14 |
Pulmonary Disease, Chronic Obstructive (9) · Asthma (1) · Disease (1) · Emergencies (1) · Hypercapnia (1) · Lung Diseases (1) · Lung Diseases, Obstructive (1) · Respiratory Insufficiency (1) · Respiratory Tract Diseases (1)
Pathologic Processes (10) · Pathological Conditions, Signs and Symptoms (10) · Chronic Disease (9) · Disease Attributes (9) · Respiratory Tract Diseases (9) · Lung Diseases (8) · Lung Diseases, Obstructive (8) · Bronchial Diseases (1) · Hypersensitivity (1) · Hypersensitivity, Immediate (1) · Immune System Diseases (1) · Respiration Disorders (1) · Respiratory Hypersensitivity (1) · Signs and Symptoms (1) · Signs and Symptoms, Respiratory (1)
Breathing Exercises (1) · Control Groups (1) · Dosage Forms (1) · Methylprednisolone (1) · Noninvasive Ventilation (1) · Oxygen (1) · Population Groups (1) · Relaxation Therapy (1) · fenoterol, ipratropium drug combination (1)
Alung Technologies (1) · Assistance Publique - Hôpitaux de Paris (1) · Belfast Health and Social Care Trust (1) · Capital Development Authority (CDA) (1) · Chang Gung Memorial Hospital (1) · David Ruttens (1) · Franciscus Gasthuis (1) · Hasselt University (1) · Hospital Authority, Hong Kong (1) · Hospital Quiron Sagrado Corazon (1) · Hôpital Universitaire Taher Sfar (1) · Koronis Biomedical Technologies (1) · Necmettin Erbakan University (1) · Peking University Third Hospital (1) · Post Graduate Institute of Medical Education and Research, Chandigarh (1)
Belgium (3) · China (2) · Hong Kong (2) · United States (2) · France (1) · India (1) · Netherlands (1) · Pakistan (1) · Taiwan (1) · Tunisia (1) · Turkey (Türkiye) (1) · United Kingdom (1)
Antonio Artigas, MD (1) · Chris Burtin, PhD (1) · David Ruttens, MD, PhD (1) · Dorien Kiers, MD, PhD (1) · Fazal Rabbi, MD (1) · Inderpaul Singh Sehgal, MD DM (1) · Nicholas Hill, MD (1) · Qingtao Zhou (1)
PMID 31291514, PMID 33419742, PMID 33854019, PMID 36680884, PMID 37976375, PMID 38261630
R44AG071430 (1)