19 completed, 1 terminated. 20 Phase 1, 1 Phase 2.
By phase and status
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Trials (filtered) newest first · largest first
All 20 trials
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|
Compare the Pharmacokinetics of Omeprazole, Rosiglitazone, and Desipramine When Administered With Avanafil in Healthy Male Subjects
Omeprazole, Rosiglitazone, Desipramine - Erectile Dysfunction | Phase 1 | Completed | 60 | 2010-04-01 | 2011-08-11 |
Assess the Effect of Food on Avanafil Pharmacokinetic (PK), to Compare 2 Oral Formulations of Avanafil,and Investigate Dose Proportionality in Healthy Male Subjects
Avanafil - Healthy | Phase 1 | Completed | 24 | 2010-04-01 | 2011-01-07 |
Drug Interaction Study of Avanafil and Enalapril or Amlodipine
avanafil and enalapril, avanafil and amlodipine - Erectile Dysfunction | Phase 1 | Completed | 48 | 2010-04-01 | 2011-08-10 |
Study the Effect of Avanafil on the Pharmacodynamics and Pharmacokinetics of Warfarin in Healthy Male Subjects
200 mg Avanafil, Placebo - Erectile Dysfunction | Phase 1 | Completed | 24 | 2010-04-01 | 2011-01-07 |
Hemodynamic Study of Avanafil and Two α-Adrenergic Blockers,Doxazosin and Tamsulosin
Tamsulosin and avanafil, Doxazosin and avanafil - Erectile Dysfunction | Phase 1 | Completed | 48 | 2010-02-01 | 2011-01-07 |
A Pharmacokinetic (PK) Study to Compare the Absorption of Two Formulations of Transdermal Testosterone Spray and Intrinsa®
Testosterone Spray 5% and 1%, Intrinsa® Patch and Testosterone Spray 5%, Intrinsa® Patch and Testosterone Spray 1% - Hypoactive Sexual Desire Disorder | Phase 1 | Terminated | 16 | 2010-02-01 | 2011-06-08 |
To Assess the Safety of Avanafil in Healthy and Hepatically Impaired Male Subjects.
avanafil - Erectile Dysfunction | Phase 1 | Completed | 27 | 2010-01-01 | 2011-01-07 |
A Phase I Crossover Study of the Hemodynamic Interactions of Avanafil & Alcohol in Healthy Male Subjects.
avanafil, alcohol - Erectile Dysfunction | Phase 1 | Completed | 15 | 2010-01-01 | 2011-01-07 |
To Compare the Pharmacokinetics of Avanafil in Subjects With Mild and Moderate Renal Impairment to Subjects With Normal Renal Function.
avanafil - Renal | Phase 1 | Completed | 24 | 2010-01-01 | 2011-01-07 |
A Pharmacokinetic Study of Avanfil in Healthy Young Male Subjects
avanafil 200mg - Avanfil ADME, Semen Exposure | Phase 1 | Completed | 32 | 2009-05-01 | 2011-01-07 |
A Study to Evaluate How VI-0521 Affect Cardiac Repolarization in Healthy Male and Female Volunteers
VI-0521 - Torsades de Pointes | Phase 1 | Completed | 112 | 2009-02-01 | 2010-01-21 |
A Drug Interaction Study of VI-0521 With Metformin, Sitagliptan and Probenecid in Healthy Subjects.
Metformin, VI-0521, Sitagliptan, Probenecid - Obesity | Phase 1 | Completed | 20 | 2009-02-01 | 2010-01-21 |
Evaluate the Effect of VI-0521 on the Pharmacokinetics of Oral Contraceptive in Healthy Female Subjects
ethinyl estradiol, norethindrone, VI-0521 - Healthy | Phase 1 | Completed | 20 | 2009-01-01 | 2009-12-02 |
A Study to Evaluate the Pharmacokinetics of VI-0521 Subjects With Renal Impairment
Topirmate and Phentermine - Renal Impairment | Phase 1 | Completed | 32 | 2008-10-01 | 2009-12-01 |
To Evaluate The Effect Of Ketoconazole, Ritonavir and Erythromycin on the Safety and Pharmacokinetics of Avanafil
Ritonavir, Ketoconazole, Erythomycin - Erectile Dysfunction | Phase 1 | Completed | 44 | 2008-10-01 | 2009-12-02 |
A Study to Evaluate the Pharmacokinetics of VI-0521 in Subjects With Hepatic Impairment
Phentermine and Topiramate - Hepatic Impairment | Phase 1 | Completed | 18 | 2008-10-01 | 2009-12-01 |
A Thorough EKG Safety Study of TA-1790 (Avanafil)
moxifloxacin, avanafil, sugar pill - Erectile Dysfunction | Phase 1 | Completed | 57 | 2008-10-01 | 2011-01-07 |
A Study of VI-0521 for the Treatment of Obstructive Sleep Apnea / Hypopnea Syndrome in Obese Adults
VI-0521, placebo - Sleep Apnea | Phase 1 / Phase 2 | Completed | 45 | 2008-08-01 | 2012-10-05 |
Pharmacokinetic Comparison of Multiple Formulations of Topiramate and Phentermine in Obese Adults
topiramate, phentermine - Obesity | Phase 1 | Completed | 64 | 2007-07-01 | 2011-06-08 |
Study to Evaluate Hemodynamic Response to to a Sublingual Dose of Glyceryl Trinitrate in Subjects Receiving TA-1790, Sildenafil Citrate, and Placebo
TA-1790, Sildenafil citrate, Placebo - Erectile Dysfunction | Phase 1 | Completed | 106 | 2004-03-01 | 2012-06-14 |
Conditions studied
Erectile Dysfunction (9) · Obesity (3) · Renal Insufficiency (1) · Sexual Dysfunctions, Psychological (1) · Sleep Apnea Syndromes (1) · Torsades de Pointes (1)
Interventions
avanafil (10) · Phentermine (2) · Amlodipine (1) · Desipramine (1) · Doxazosin (1) · Enalapril (1) · Ethanol (1) · Ethinyl Estradiol (1) · Ketoconazole (1) · Metformin (1) · Moxifloxacin (1) · Nitroglycerin (1) · Norethindrone (1) · Omeprazole (1) · Probenecid (1)
Countries
United States (14)
Top investigators
Shiyin Yee, PhD (9) · Shiyin Yee (5) · Charles Bowden, MD (1) · Chuck Bowden, M.D. (1) · Craig Peterson, MS (1) · Mark Allison, MD (1) · Scott Sharples, M.D. (1) · Scott Sharples, MD (1) · Wesley W Day, PhD (1)