12 completed, 5 terminated, 3 unknown, 3 withdrawn. 23 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 23 | Completed 12, Terminated 5, Unknown 3, Withdrawn 3 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluating Sublingual Dexmedetomidine For Moderate To Severe Agitation In Inpatients With Schizophrenia Or Bipolar Disorder Dexmedetomidine, Lorazepam 2 MG/ML - Schizophrenia Agitation, Schizo Affective Disorder | Phase 4 | Unknown | Temple University | 32 | 2023-07-01 | 2023-10-23 |
| Comparison of Time to Extubation Using Sugammadex or Neostigmine neostigmine/glycopyrrolate, sugammadex - Neuromuscular Blockade, Chronic Obstructive Pulmonary Disease | Phase 4 | Completed | Temple University | 58 | 2021-04-08 | 2024-03-13 |
| Dosing Strategies for de Novo Once-daily Extended Release Tacrolimus (LCPT) in Kidney Transplant Recipients Tacrolimus Extended Release Oral Tablet [Envarsus] 0.13mg/kg/day initiated within post-operative day 3 after kidney transplant - Kidney Transplant | Phase 4 | Completed | Temple University | 36 | 2018-11-12 | 2023-05-11 |
| Investigation of Cannabinoid Receptor Agonist Dronabinol in Patients With Functional Chest Pain Dronabinol, Placebo - Esophageal Diseases | Phase 4 | Withdrawn | Temple University | 2017-06-21 | 2019-09-26 | |
| Liraglutide for HIV-associated Neurocognitive Disorder Liraglutide - HIV Infection, Diabetes Mellitus Type 2 | Phase 4 | Terminated | Temple University | 4 | 2016-09-01 | 2022-07-29 |
| The Intra-arterial Vasospasm Trial Nicardipine, Verapamil, Nicardipine + Verapamil + Nitroglycerin - Cerebral Vasospasm | Phase 4 | Terminated | Peng Roc Chen, MD | 92 | 2016-08-29 | 2025-05-11 |
| Lidocaine and Triamcinolone vs Saline Trigger Point Injection for Treatment of Chronic Abdominal Wall Pain Triamcinolone, Placebo, Lidocaine - Chronic Abdominal Wall Pain, Abdominal Cutaneous Nerve Entrapment Syndrome | Phase 4 | Withdrawn | Temple University | 2016-05-01 | 2016-12-05 | |
| Comparison of Voice Therapy and Antireflex Therapy in LPR Omeprazole, Lansoprazole, Esomeprazole, Rantidine, Voice therapy, Combination of anti-reflux medication and voice therapy - Laryngopharyngeal Reflux | Phase 4 | Withdrawn | Temple University | 2016-05-01 | 2018-05-18 | |
| Chronic Hypertension and Pregnancy (CHAP) Project Anti-hypertensive therapy, No anti-hypertensive therapy (unless BP is severe) - Hypertension | Phase 4 | Completed | University of Alabama at Birmingham | 2408 | 2015-06-01 | 2023-05-17 |
| Effects of Liraglutide on ER Stress in Obese Patients With Type 2 Diabetes Liraglutide - Type 2 Diabetes | Phase 4 | Unknown | Temple University | 12 | 2014-05-01 | 2022-07-29 |
| Intervention to Promote Weight Loss in Latinas At-risk for Diabetes Promotora-led Intervention, Metformin Therapy, Usual Care - Diabetes | Phase 4 | Completed | Temple University | 92 | 2013-09-01 | 2020-12-22 |
| Sitagliptin Therapy in Hospitalized Patients With Type 2 Diabetes Sitagliptin, Basal Bolus, Metformin and Sitagliptin - Type 2 Diabetes | Phase 4 | Completed | Emory University | 292 | 2013-08-01 | 2017-05-30 |
| Telephone Based Management of Hyperlipidemia Self Monitoring Lipid Analyzer - Hyperlipidemia | Phase 4 | Completed | Temple University | 70 | 2010-11-01 | 2026-04-07 |
| Kaletra and Maraviroc in Antiretroviral Therapy (ART)-Naive Patients (KALMAR Study) lopinavir/ritonavir plus maraviroc - HIV Infections | Phase 4 | Terminated | Temple University | 1 | 2010-04-01 | 2020-11-02 |
| Miralax (PEG 3350) vs. Golytely as Bowel Preparation for Screening Colonoscopy PEG-3350 and Gatorade, Golytely 4 liters - Colon Cancer | Phase 4 | Completed | Temple University | 136 | 2010-04-01 | 2017-09-13 |
| Impact of Conversion From Tacrolimus to Sirolimus in African American Renal Transplant Recipients sirolimus - Glomerular Filtration Rate, Chronic Allograft Nephropathy | Phase 4 | Unknown | Temple University | 50 | 2009-09-01 | 2009-10-21 |
| Strict Glycemic Control by Insulin Infusion:Observations on Emergency Department Initiation Insulin - Hyperglycemia | Phase 4 | Completed | Temple University | 27 | 2007-03-01 | 2017-03-16 |
| Effect of Tegaserod on Orocecal Transit in Elderly Chronic Constipation Patients Tegaserod - Chronic Constipation | Phase 4 | Terminated | Novartis | 60 | 2006-07-01 | 2016-03-04 |
| Lansoprazole Preventing Gastroduodenal Stress Ulcerations Lansoprazole - Patients Undergoing Elective Coronary Artery Bypass Graft | Phase 4 | Terminated | Temple University | 40 | 2005-09-01 | 2008-01-11 |
| Rabeprazole Protection of Aspirin Induced Gastric Damage. Rabeprazole - Normal Subjects | Phase 4 | Completed | Temple University | 30 | 2005-09-01 | 2008-01-11 |
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Diabetes Mellitus (3) · Diabetes Mellitus, Type 2 (3) · Obesity (3) · HIV Infections (2) · Weight Loss (2) · Anxiety Disorders (1) · Bipolar Disorder (1) · Colonic Neoplasms (1) · Constipation (1) · Esophageal Diseases (1) · Hyperglycemia (1) · Hyperlipidemias (1) · Hypertension (1) · Laryngopharyngeal Reflux (1) · Lung Diseases (1)
Caloric Restriction (2) · Lansoprazole (2) · Liraglutide (2) · Cognitive Behavioral Therapy (1) · Dexmedetomidine (1) · Diet, Carbohydrate-Restricted (1) · Dronabinol (1) · Electrolytes (1) · Esomeprazole (1) · Glycopyrrolate (1) · Insulin (1) · Insulin Aspart (1) · Insulin Glargine (1) · Insulin Lispro (1) · Labetalol (1)
United States (22) · Australia (1)
Holly Wyatt, MD (2) · James Hill, PhD (2) · Robert S Fisher, MD (2) · Samuel Klein, MD (2) · Adam Diamond, PharmD (1) · Ajaykumar D Rao, MD (1) · Alan Tita, MD, PhD (1) · Cherie Vaz, MD Dipl ABOM (1) · Ellen Hauck, DO PhD (1) · Frank Friedenberg, MD (1) · Gary Cutter, PhD (1) · Gary D Foster, PhD (1) · Gary Foster, PhD (1) · Guillermo Umpierrez, MD (1) · Henry Parkman, M.D. (1)
PMID 12161727, PMID 16481828, PMID 20082927, PMID 20679559, PMID 21760633, PMID 21908799, PMID 22653255, PMID 22711499, PMID 27964837, PMID 35363951, PMID 37437694, PMID 37769314, PMID 38781591, PMID 38949541
R01AT001103 (2), R01MH064484 (1), U01HL119242 (1)