116 completed, 37 unknown, 21 recruiting, 10 terminated. 94 Not applicable, 31 Phase 3, 20 Phase 2, 11 Phase 1, 7 Phase 4.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| FEEL-GOOD: A Multicenter Trial of a Mindfulness-Based Group Therapy in Young Adults With Early Psychosis FEEL GOOD, Treatment as Usual (TAU) - Delusional Disorder, Brief Psychotic Disorder | Not applicable | Recruiting | Stephanie Mehl | 252 | 2026-05-27 | 2026-09-22 |
| Sodium Bicarbonate for Critically Ill Patients With Metabolic Acidosis and Acute Kidney Injury Sodium Bicarbonate 8.4% Solution for Injection, Balanced crystalloid solution - Acute Kidney Injury, Metabolic Acidosis | Phase 4 | Recruiting | Universität Münster | 660 | 2026-05-07 | 2026-09-04 |
| Ovarian Cancer Screening and AI ChatGPT - Control, ChatGPT - Evidence-Based Screening Discussion - Ovarian Cancer Screening Recommendations by Gynecologists | Not applicable | Completed | Charite University, Berlin, Germany | 300 | 2026-03-27 | 2026-10-20 |
| STOP-PKD: SGLT2-inhibition to Improve Prognosis in Polycystic Kidney Disease Dapagliflozin 10 mg, Matching Placebo - Polycystic Kidney, Autosomal Dominant | Phase 3 | Recruiting | University of Cologne | 420 | 2025-12-16 | 2026-07-28 |
| Group Therapy for Major Depression: Comparing Expectation-Focused and Reward-Focused Psychotherapy Approaches Expectation-Focused Psychotherapeutic Intervention, Reward Enhancement and Activation Therapy - Major Depressive Disorder (MDD) | Not applicable | Recruiting | Philipps University Marburg | 150 | 2025-10-13 | 2026-02-10 |
| Biological Determinants and Neural Compensation of Dysphagia in Parkinson's Disease Parkinsons Disease (PD), Oropharyngeal Dysphagia | Recruiting | Heinrich-Heine University, Duesseldorf | 100 | 2025-09-01 | 2025-12-23 | |
| Assessing Declined Liver Grafts With Normothermic Machine Perfusion to Reduce Transplant Waiting Time Quality Assessment with Normothermic Machine Perfusion (NMP) - Liver Transplantation, Liver Diseases | Not applicable | Recruiting | Charite University, Berlin, Germany | 186 | 2025-06-02 | 2026-04-15 |
| Reducing Cardiac-surgery Associated Acute Kidney Injury Occurence by Administering Angiotensin II Angiotensin II, Noradrenalin - Cardiac Surgery, Vasoplegia | Phase 3 | Recruiting | Universität Münster | 1022 | 2025-03-31 | 2025-07-18 |
| Effect of Chronic Exercise on Human Thermogenic Adipose Tissue & Elucidation of Mechanisms Endurance Training - Endurance Training, No Training | Not applicable | Completed | Technical University of Munich | 24 | 2025-01-01 | 2025-12-23 |
| Prevention of Mental Disorders Through Self-efficacy Interventions Cognitive-Behavioral Intervention to increase Self Efficacy, Placebo: Weekly Recap and Group Discussion on Psychological Experiments - Depression Disorders, Affective Disorders | Not applicable | Recruiting | Health and Medical University Potsdam | 378 | 2024-11-18 | 2024-12-18 |
| Liquid Biopsy Under PSMA Radioligand Therapy Prostate Cancer Metastatic Castration-Resistant, Prostate Cancer | Recruiting | Wuerzburg University Hospital | 100 | 2024-09-01 | 2025-08-12 | |
| Group Intervention for Interpersonal Skills Kiesler Circle Training (KCT), Cognitive Behavioral Therapy (CBT) - Depressive Disorder, Anxiety Disorder | Not applicable | Completed | Charite University, Berlin, Germany | 158 | 2024-07-03 | 2026-09-02 |
| Social Media Usage in Adolescent Girls Menstrual Cycle, Oral Contraceptive | Unknown | International Research Training Group 2804 | 70 | 2024-05-29 | 2024-05-23 | |
| Dopamine, Reward Learning and Sex Hormones Levodopa administration, Placebo administration - Hormonal Changes, Menstrual Cycle | Not applicable | Unknown | University Hospital Tuebingen | 90 | 2024-05-01 | 2024-05-09 |
| Breast Cancer & Antiestrogenic Therapy & Brain Tamoxifen, Letrozole, Letrozole + GnRH - Breast Cancer Female, Healthy Female | Unknown | International Research Training Group 2804 | 180 | 2024-04-01 | 2024-04-04 | |
| Negative Emotionality and Epigenetics During Puberty Stress - Puberty, Healthy | Recruiting | International Research Training Group 2804 | 100 | 2024-03-26 | 2024-11-15 | |
| Phase 3 Clinical Trial With Dapagliflozin in Chronic Kidney Disease in Adolescents and Young Adult Patients Dapagliflozin, Placebo - Chronic Kidney Failure in Children and Young Adults | Phase 3 | Recruiting | University Hospital Goettingen | 102 | 2024-03-25 | 2026-10-16 |
| Estradiol and Stress Reactivity in Women Estradiol Valerate, Placebo - Stress vs. Control, Estradiol vs. Placebo | Unknown | International Research Training Group 2804 | 74 | 2024-03-07 | 2024-03-08 | |
| Mentalization-based Treatment Versus Bona-fide Treatment for Patients With Borderline Personality Disorder in Germany Mentalization-Based Treatment (MBT), Bona-Fide Treatment in Germany (BFT) - Borderline Personality Disorder | Not applicable | Recruiting | Heidelberg University | 304 | 2024-02-28 | 2024-05-10 |
| Oxytocin and Reward Processing in Women Intranasal oxytocin administration, Intranasal placebo administration - Menstrual Cycle, Hormonal Contraception | Not applicable | Recruiting | International Research Training Group 2804 | 100 | 2024-02-16 | 2024-02-28 |
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Stress Disorders, Post-Traumatic (12) · Depression (10) · Depressive Disorder, Major (9) · Schizophrenia (7) · Acute Kidney Injury (5) · Sepsis (5) · Stroke (5) · Alcoholism (4) · Emotional Regulation (4) · Insulin Resistance (4) · Motor Activity (4) · Obesity (4) · Pain (4) · Tobacco Use Disorder (4) · Anorexia Nervosa (3)
Cognitive Behavioral Therapy (7) · Fluorouracil (3) · Interpersonal Psychotherapy (3) · Observation (3) · Transcranial Direct Current Stimulation (3) · Albumins (2) · Angiotensin II (2) · Bronchoscopy (2) · Cytarabine (2) · Estradiol (2) · Exercise (2) · Ghrelin (2) · Granulocyte-Macrophage Colony-Stimulating Factor (2) · Leucovorin (2) · Oxaliplatin (2)
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Alexander Zarbock, MD (4) · Markus Ploner, Prof. Dr. med. (3) · Anette E Buyken, Prof. Dr. (2) · Birgit Derntl, Prof. (2) · Eva-Lotta Brakemeier, Prof. Dr. (2) · Joerg Schirra, MD (2) · Julia A. Glombiewski, Dr. (2) · Katrin Kuhnt, Dr. rer. nat (2) · Knut Mai, Prof (2) · Thomas Elbert, Prof. Dr. (2) · Achim J Kaasch, MD (1) · Alexander Braunsperger, PhD candidate (1) · Alexandra Kleiman, Dr. (1)
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