74 completed, 34 unknown, 18 recruiting, 10 terminated. 159 Phase 3, 24 Phase 2.
Follow Tranexamic Acid: new trials by email Literature Review of Tranexamic Acid trials Research Report on Tranexamic Acid
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| HTO and Tranexamic Acid Study Tranexamic Acid, Routine medial opening wedge high tibial osteotomy - Osteoarthritis, Knee | Phase 3 | Not yet recruiting | Western University, Canada | 200 | 2027-01-01 | 2026-09-17 |
| Extended Post-Operative Oral Tranexamic Acid Dosing After ACL Reconstruction Tranexamic Acid, Placebo - Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture | Phase 3 | Not yet recruiting | Dave Bernholt | 100 | 2026-11-01 | 2026-10-26 |
| Tranexamic Acid to Reduce Blood Loss After Varus Derotation Osteotomy Tranexamic Acid (IV), Placebo - Cerebral Palsy, Hip Surgery Corrective | Phase 3 | Not yet recruiting | Murdoch Childrens Research Institute | 52 | 2026-11-01 | 2026-10-14 |
| Traumatic Injury Clinical Trial Evaluating Tranexamic Acid in Children: An Efficacy Study Tranexamic acid injection - Brain Injuries, Traumatic, Wounds and Injury | Phase 3 | Not yet recruiting | Daniel Nishijima, MD, MAS | 2000 | 2026-10-01 | 2025-12-15 |
| Tranexamic Acid for Anaemia Trial Tranexamic Acid 500 MG, Placebo - Anaemia | Phase 3 | Recruiting | London School of Hygiene and Tropical Medicine | 4000 | 2026-08-10 | 2026-08-17 |
| Perioperative Haemostasis, Procedure-Related Pain After Physiological or Pharmacological Modifications of Local Anaesthesia Around the Eyes Sodium Bicarbonate (NaHCO3), Warmed lignocaine, Hyaluronidase Injection - Dermatochalasis of Upper Eyelid, Blepharoplasty | Phase 3 | Not yet recruiting | Prince of Wales Hospital, Shatin, Hong Kong | 80 | 2026-08-01 | 2026-08-03 |
| The Use of Tranexamic Acid in the Treatment of Symptomatic Subdural Hematoma Tranexamic acid (TXA), Placebo - Subdural Hematoma | Phase 3 | Recruiting | Unity Health Toronto | 130 | 2026-05-20 | 2026-05-29 |
| Investigating the Efficacy of Tranexamic Acid as a Prophylactic Agent in Reducing Postpartum Hemorrhage Among Patients Undergoing Cesarean Section in SQUH tranexamic acid (1 g diluted in 100 mL of 0.9% saline, Normal (0.9%) saline - Post Partum Haemorrhage | Phase 3 | Not yet recruiting | Sultan Qaboos University | 88 | 2026-05-01 | 2026-04-01 |
| Effects of Oral Tranexamic Acid on Short Term Postoperative Outcomes Following Total Shoulder Arthroplasty oral tranexamic acid, Placebo - Shoulder Arthroplasty | Phase 3 | Recruiting | University of Alabama at Birmingham | 60 | 2026-04-20 | 2026-04-28 |
| Evaluation of the Efficacy of Oral Tranexamic Acid and Glutathione-assisted Microneedling in Treatment of Melasma microneedling, Oral tranexamic acid, Glutathione - Melasma | Phase 2 / Phase 3 | Not yet recruiting | Assiut University | 42 | 2026-02-01 | 2026-03-04 |
| Adjuvant Tranexamic Acid (TXA) Versus Surgery Alone for Adult Patients With Chronic Subdural Hematoma (CSDH) Tranexamic Acid (Cyklokapron) - Chronic Subdural Hematoma | Phase 2 / Phase 3 | Recruiting | St. Olavs Hospital | 274 | 2025-12-10 | 2026-07-17 |
| Tranexamic Acid : Nebulization vs IV Route for Hemoptysis Tranexamic Acid (TXA) - Hemoptysis, NEBULIZATION | Phase 2 / Phase 3 | Completed | University of Health Sciences Lahore | 172 | 2025-08-01 | 2025-11-28 |
| Bleeding Reduction in Acute and Chronic Kidney Patients Having Surgery (BRACKETS) Pilot Trial Desmopressin Injectable Solution, Tranexamic Acid Injectable Product, Placebo - Chronic Kidney Diseases, Acute Kidney Injury | Phase 3 | Recruiting | Hamilton Health Sciences Corporation | 100 | 2025-06-09 | 2026-05-22 |
| Decreasing Postoperative Blood Loss and Seizures by Timing of Intravenous Tranexamic Acid 2 Pilot Trial Before CPB Tranexamic Acid, After CPB Tranexamic Acid, Before CPB Placebo - Bleeding, Surgical Blood Loss | Phase 3 | Unknown | Hamilton Health Sciences Corporation | 40 | 2025-01-01 | 2024-10-02 |
| Massive Transfusion in Children-2: A Trial Examining Life Threatening Hemorrhage in Children Low Titer Group O Whole Blood (LTOWB), Placebo, Tranexamic Acid (TXA) - Hemorrhagic Shock, Trauma Injury | Phase 3 | Recruiting | Philip Spinella | 1000 | 2024-11-01 | 2026-09-17 |
| Comparing Intramyometrial Tranexamic Acid and Oxytocin for Blood Loss in Cesarean Section Tranexamic acid injection, Oxytocin - Cesarean Section Complications, Tranexamic Acid | Phase 3 | Unknown | Cairo University | 150 | 2024-10-01 | 2024-09-05 |
| Extended Oral Tranexamic Acid After Total Knee Arthroplasty Tranexamic acid, Placebo - Osteo Arthritis Knee, Pain, Postoperative | Phase 3 | Enrolling by invitation | Campbell Clinic | 120 | 2024-09-17 | 2026-08-13 |
| Tranexamic Acid for Reduction of Transfusion in Abdominal Surgery Tranexamic Acid, Placebo - Surgical Blood Loss, Transfusion-dependent Anemia | Phase 3 | Completed | Ulrich Ronellenfitsch, MD | 892 | 2024-06-17 | 2026-10-07 |
| Tranexamic Acid to Prevent Heavy Bleeding After Childbirth in Women At Higher Risk Tranexamic acid, Placebo - Postpartum Hemorrhage | Phase 3 | Recruiting | London School of Hygiene and Tropical Medicine | 30000 | 2024-04-22 | 2025-03-11 |
| Protest Trial: TXA vs Saline Tranexamic Acid, Saline (placebo) - Lung Transplant, Complications Surgical | Phase 3 | Enrolling by invitation | Corewell Health West | 94 | 2024-04-16 | 2026-07-21 |
Showing 20 of 159. Sign in to see all of them.
Hemorrhage (42) · Postpartum Hemorrhage (18) · Blood Loss, Surgical (13) · Menorrhagia (6) · Anemia (5) · Brain Injuries, Traumatic (5) · Hematoma, Subdural, Chronic (5) · Hip Fractures (5) · Melanosis (5) · Neoplasms (5) · Postoperative Hemorrhage (5) · Hemoptysis (4) · Osteoarthritis (4) · Pain (4) · Pain, Postoperative (4)
London School of Hygiene and Tropical Medicine (8) · Assiut University (5) · Ferring Pharmaceuticals (4) · Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau (4) · Ain Shams University (3) · Cairo University (3) · McMaster University (3) · Ottawa Hospital Research Institute (3) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (2) · Azienda U.S.L. 1 di Massa e Carrara (2) · Cristina Martinez (2) · Hamilton Health Sciences Corporation (2) · Mount Sinai Hospital, Canada (2) · Northwestern University (2) · Population Health Research Institute (2)
United States (39) · Canada (24) · France (11) · Spain (10) · Egypt (9) · China (6) · Pakistan (6) · Australia (5) · India (5) · United Kingdom (5) · Netherlands (4) · Germany (3) · Hong Kong (3) · Italy (3) · Malaysia (3)
Haleema Shakur-Still (3) · Andre Lamy, MD (2) · Ian Roberts (2) · Paul Karanicolas, MD PhD (2) · Aguilera Roig, Xavier (1) · Aguilera X, M.D (1) · Ahmad M BahaaEldin, MD (1) · Ahmed N Afifi, MD (1) · Ahmed N Shaker, MD (1) · Alan Tinmouth, MD (1) · Alan Tinmouth, MD MSc (1) · Amal Ramadan, MBBCh (1)
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