18 completed, 7 recruiting, 7 unknown, 2 suspended. 38 Phase 3, 7 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 38 | Completed 18, Recruiting 7, Unknown 7, Suspended 2, Terminated 2, Active not recruiting 1, Withdrawn 1 |
| Phase 2 | 7 | Completed 3, Recruiting 1, Suspended 1, Unknown 1, Withdrawn 1 |
Follow Norepinephrine: new trials by email Literature Review of Norepinephrine trials Research Report on Norepinephrine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Low-dose Arginine-vasopressin Supplementation on Post-transplant Acute Kidney Injury After Liver Transplantation (AVENIR Trial) Arginine vasopressin, Norepinephrine - Acute Kidney Injury Post Liver Transplantation | Phase 3 | Recruiting | Assistance Publique - Hôpitaux de Paris | 304 | 2025-04-16 | 2026-02-05 |
| Norepinephrine and Vasopressin for Rescue Versus Early Vasopressin for Vasopressor Dependent Sepsis Early Vasopressin, Norepinephrine and Vasopressin for Rescue - Septic Shock | Phase 3 | Recruiting | Hospital do Coracao | 2800 | 2024-11-21 | 2026-01-30 |
| Preventing Cardiovascular Collapse With Vasopressors During Tracheal Intubation Noradrenaline - Critical Illness, Respiratory Failure | Phase 3 | Recruiting | University of Turin, Italy | 420 | 2024-08-01 | 2025-03-28 |
| The Effect of Early Norepinephrine on Stroke Volume Index, Cardiac Index, Lactate, and Arterial Elastance in Pediatric Septic Shock Norepinephrine, Ringer's Lactate - Septic Shock, Sepsis | Phase 2 / Phase 3 | Completed | Universitas Indonesia | 42 | 2024-03-25 | 2024-06-20 |
| Vasopressor Impact on Brain Circulation, Organ Blood Flow and Tissue Oxygenation During Anesthesia Noradrenalin, Phenylephrine - Hypotension | Phase 2 / Phase 3 | Recruiting | University of Aarhus | 32 | 2023-12-20 | 2026-03-19 |
| Early Initiated Vasopressor Therapy in the Emergency Department Noradrenaline - Shock, Shock, Septic | Phase 3 | Recruiting | Odense University Hospital | 320 | 2023-12-08 | 2025-07-01 |
| Evaluation of the Superiority of VAsopressin Versus NOradrenaline in the Management of Patients at Risk of Kidney Failure Undergoing Cardiac Surgery With Extracorporeal Circulation Vasopressin, Norepinephrine, Collection of clinical data - Scheduled Cardiac Surgery With Extracorporeal Circulation, Vasoplegic Syndrome | Phase 3 | Active not recruiting | Centre Hospitalier Universitaire Dijon | 840 | 2023-01-02 | 2025-12-22 |
| Early Vasopressors in Sepsis Norepinephrine, Balanced Crystalloid - Sepsis | Phase 3 | Recruiting | NHS Greater Glasgow and Clyde | 1006 | 2022-10-11 | 2026-02-12 |
| Clinical Trial Comparing Noradrenaline (NA) Plus Placebo Versus Noradrenaline Plus Terlipressin (TP) in Septic Shock Noradrenaline plus Terlipressin - Septic Shock | Phase 3 | Unknown | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | 152 | 2022-10-11 | 2023-04-27 |
| Comparative Efficacity of Ephedrine Versus Norepinephrine to Correct Anesthesia Induction Related Hypotension Ephedrine, Norepinephrine - Hypotension on Induction | Phase 3 | Unknown | Brugmann University Hospital | 60 | 2022-09-15 | 2022-09-16 |
| Norepinephrine for Prevention of Intraoperative Hypotension in Infants Undergoing Kasai Portoenterostomy Norepinephrine Bitartrate, Placebo - Anesthesia, Pediatrics | Phase 3 | Completed | Kasr El Aini Hospital | 31 | 2022-08-28 | 2024-07-09 |
| Using Vasopressor Medication to Support Blood Pressure During Intubation Procedure Norepinephrine, Lactated Ringers, Intravenous, normal saline - Respiratory Failure, Hypotension and Shock | Phase 3 | Completed | Wright State University | 42 | 2022-08-09 | 2024-07-15 |
| Lung Ultrasound-guided Hemodynamic Optimization noradrenaline and vascular filling, pulmonary ultrasound after vascular filling - Lung Ultrasound, Goal Directed Therapy | Phase 3 | Recruiting | Centre Hospitalier Universitaire, Amiens | 350 | 2022-07-28 | 2025-05-28 |
| Therapeutic Study Evaluating the Efficacy of Noradrenaline in the Prevention of Hypotension Related to Intubation for Cardiac or Thoracic Surgery noradrenaline - Cardiac Disorder, Hypotension | Phase 3 | Completed | Nantes University Hospital | 211 | 2022-04-27 | 2024-03-07 |
| Evaluation of the Early Use of Norepinephrine in Major Abdominal Surgery on Postoperative Organ Dysfunction Ephedrine, Norepinephrine - Norepinephrine, Hypotension | Phase 3 | Completed | Centre Hospitalier Universitaire, Amiens | 500 | 2021-11-17 | 2025-12-03 |
| Hemodynamic Effect of Norepinephrine Versus Vasopressin on the Pulmonary Circulation in Cardiac Surgery Patients: Vasopressin, Norepinephrine - Cardiac Disease | Phase 3 | Completed | The Cleveland Clinic | 153 | 2020-11-05 | 2026-10-27 |
| Dopamine Versus Norepinephrine Under General Anesthesia norepinephrine, dopamine - Anesthesia, Infant | Phase 3 | Completed | Children's Hospital of Fudan University | 60 | 2020-10-10 | 2021-10-22 |
| Methylene Blue and Microcirculation in Septic Shock Methylene Blue, Norepinephrine infusion - Septic Shock | Phase 3 | Unknown | Cairo University | 32 | 2020-03-10 | 2020-03-05 |
| Comparison of Phenylephrine and Norepinephrine for Spinal-induced Hypotension Norepinephrine, Phenylephrine - Spinal Induced-hypotension | Phase 3 | Completed | Tribhuvan University Teaching Hospital, Institute Of Medicine. | 80 | 2019-11-10 | 2021-03-09 |
| Norepinephrine and Phenylephrine, Which Better for Elderly? norepinephrine, Phenylephrine - Hypotension | Phase 3 | Unknown | The Second Affiliated Hospital of Dalian Medical University | 100 | 2019-10-06 | 2019-10-08 |
Showing 20 of 38. Sign in to see all of them.
Shock, Septic (12) · Hypotension (8) · Sepsis (5) · Shock (5) · Diabetes Insipidus (3) · Critical Illness (2) · Heart Diseases (2) · Respiratory Insufficiency (2) · Vasoplegia (2) · Biliary Atresia (1) · Brain Ischemia (1) · Cognitive Dysfunction (1) · Delirium (1) · Disease (1) · Emergencies (1)
Centre Hospitalier Universitaire, Amiens (3) · Assistance Publique - Hôpitaux de Paris (2) · Cairo University (2) · Post Graduate Institute of Medical Education and Research, Chandigarh (2) · The Second Affiliated Hospital of Dalian Medical University (2) · University of Sao Paulo (2) · Assiut University (1) · Brugmann University Hospital (1) · Central Hospital, Nancy, France (1) · Centre Hospitalier Universitaire Dijon (1) · Children's Hospital of Fudan University (1) · China International Neuroscience Institution (1) · Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico (1) · Fundación Pública Andaluza para la gestión de la Investigación en Sevilla (1) · Hospital General de Ciudad Real (1)
France (10) · Egypt (4) · United States (4) · Brazil (3) · China (3) · Denmark (2) · India (2) · Italy (2) · Spain (2) · Belgium (1) · Indonesia (1) · Ireland (1) · Nepal (1) · Netherlands (1) · Sweden (1)
Ahmed Mukhtar, Professor (2) · Alessandro Santini, MD (1) · Antonio Pesenti, MD (1) · Bruno M Tomazini, MD (1) · Cristiane M Zambolim, MD (1) · David Alan Schoenfeld, PhD (1) · Djillali Annane, MD, PhD (1) · Eric Bellissant, MD, PhD (1)
PMID 27841822, PMID 11555538, PMID 16616623, PMID 17560680, PMID 17720019, PMID 18305265, PMID 19534818, PMID 19841897, PMID 19851126, PMID 20486907, PMID 21615299, PMID 23394211, PMID 23601499, PMID 24491036, PMID 24652962, PMID 25179459, PMID 25407570, PMID 25673576, PMID 25947955, PMID 27481679, PMID 27483065, PMID 28120005, PMID 28367008, PMID 2916660, PMID 29452808, PMID 29753517, PMID 30243062, PMID 31461138, PMID 31529354, PMID 31585796, PMID 31609774, PMID 32894044, PMID 32931198, PMID 33755076, PMID 36507525, PMID 36688507, PMID 37145232, PMID 38492626, PMID 38684243, PMID 38992663, PMID 40132839, PMID 40250622, PMID 40315385, PMID 41381314, PMID 41632536, PMID 42093058, PMID 42573415, PMID 9403749
2014 (1), 2017 (1), 2023 (1)