22 completed, 2 recruiting, 2 terminated, 1 withdrawn. 27 Phase 2, 5 Phase 3, 3 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 27 | Completed 22, Recruiting 2, Terminated 2, Withdrawn 1 |
| Phase 3 | 5 | Completed 3, Recruiting 1, Terminated 1 |
| Phase 1 | 3 | Completed 3 |
Follow Nicotine patch: new trials by email Literature Review of Nicotine patch trials Research Report on Nicotine patch
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluating Smoking Cessation Interventions for PWH in South Africa Varenicline, Nicotine patch, Nicotine gum - Smoking Cessation, HIV | Phase 2 / Phase 3 | Recruiting | Johns Hopkins University | 660 | 2023-11-27 | 2026-10-19 |
| Exenatide for Smoking Cessation and Prevention of Weight Gain Exenatide 2 milligram (mg) Injection, Placebo, Nicotine patch - Smoking Cessation, Weight Gain | Phase 2 | Completed | The University of Texas Health Science Center, Houston | 140 | 2022-12-07 | 2026-03-23 |
| Mobile Health Technology for Personalized Tobacco Cessation Support in Laos Nicotine patch, Self-help materials (to support smoking cessation), Smartphone-based automated treatment for smoking cessation - Cigarette Smoking | Phase 2 | Recruiting | University of Oklahoma | 500 | 2022-04-27 | 2025-08-15 |
| Mobile Health Technology for Personalized Tobacco Cessation Support Among Cancer Survivors in Laos Nicotine patch, Self-help materials (to support smoking cessation), Smartphone-based automated treatment for smoking cessation - Cigarette Smoking | Phase 2 | Completed | University of Oklahoma | 80 | 2022-04-20 | 2024-08-28 |
| Heart Rate Variability Biofeedback for Smoking Cessation Treatment Cognitive-Behavioral Smoking Cessation, Heart Rate Variability Biofeedback, Nicotine patch - Tobacco Smoking | Phase 2 | Completed | Rutgers, The State University of New Jersey | 28 | 2021-11-29 | 2024-05-01 |
| Impact of Alternative Nicotine-Delivery Products on Combustible Cigarette Use Juul Electronic cigarette, Very Low Nicotine Cigarettes, Active Nicotine Patch - Nicotine Dependence | Phase 2 | Completed | University of Wisconsin, Madison | 209 | 2020-09-09 | 2023-05-25 |
| Heart Rate Variability Biofeedback for Smoking Cessation Cognitive-Behavioral Smoking Cessation, Heart Rate Variability Biofeedback (HRVB), Transdermal Nicotine patch - Tobacco Smoking | Phase 2 | Completed | Rutgers, The State University of New Jersey | 10 | 2019-04-24 | 2020-08-25 |
| Treating Smokers With Mental Illness Nicotine patch, Nicotine lozenge, Therapy - Smoking Cessation, Cigarette Smoking | Phase 2 | Completed | University of Minnesota | 38 | 2019-03-01 | 2021-05-25 |
| The Role of Nicotine Dose and Route of Delivery in Affecting Adoption of E-cigarettes and Reducing Exposure to Toxic Combustion Products Nicotine patch, Placebo patch, E-cigarettes - Nicotine Dependence, Cigarettes | Phase 2 | Completed | Duke University | 94 | 2018-08-06 | 2023-02-08 |
| Electronic Nicotine Delivery Systems as a Smoking Cessation Treatment Nicotine patch, ENDS, Placebo patch - Nicotine Dependence | Phase 2 | Withdrawn | Duke University | 2018-07-01 | 2018-09-12 | |
| PRecision Interventions for SMoking in the SCCS Nicotine patch, Varenicline, Nicotine metabolism - Tobacco Use Cessation | Phase 2 / Phase 3 | Completed | Vanderbilt University Medical Center | 67 | 2018-05-18 | 2020-06-01 |
| Safety and Efficacy Study of the NRT CQSS2 System for Smoking Cessation in Treatment-Seeking Subjects CQSS2, NicoDerm CQ Patch - Smoking Cessation | Phase 2 | Completed | Chrono Therapeutics, Inc. | 220 | 2017-08-07 | 2017-12-04 |
| Neuroimaging Reward, Behavioral Treatment, and Smoking Cessation Nicotine Patch, SPECTRUM Nicotine Research Cigarettes (.03 mg), Behavioral Activation - Smoking | Phase 1 / Phase 2 | Completed | Maggie M Sweitzer, PhD | 35 | 2017-02-01 | 2022-06-28 |
| Combination Nicotine Patch / Lorcaserin for Smoking Cessation lorcaserin, nicotine patch, placebo lorcaserin - Nicotine Dependence | Phase 2 | Completed | Duke University | 97 | 2016-11-08 | 2019-05-07 |
| Exenatide Once Weekly for Smoking Cessation Exenatide, NRT, Counseling - Smoking Cessation | Phase 1 / Phase 2 | Completed | The University of Texas Health Science Center, Houston | 84 | 2016-07-01 | 2021-01-28 |
| Project Impact 2: A Culturally Tailored Smoking Cessation Intervention for Latino Smokers Nicotine Patch, Questionnaires, Carbon Monoxide (CO) Test - Tobacco Use Cessation, Cancer Prevention | Phase 1 / Phase 2 | Completed | M.D. Anderson Cancer Center | 26 | 2015-11-02 | 2020-03-10 |
| Efficacy and Neural Correlates of Personalized Treatment With Transdermal Nicotine Replacement Nicotine patch, Nicotine mouthspray - Tobacco Use Disorder, Nicotine Dependence | Phase 2 / Phase 3 | Terminated | Centre for Addiction and Mental Health | 18 | 2015-07-01 | 2018-07-19 |
| Evaluation of Moclobemide, a Reversible MAO-A Inhibitor, as an Adjunct to Nicotine Replacement Therapy in Female Smokers Nicotine Patch, Moclobemide - Nicotine Dependence | Phase 2 | Completed | Jed E. Rose | 76 | 2013-09-01 | 2017-08-23 |
| Proof-Of-Concept Investigation With a Neurosteroid Analog (Ganaxolone) as a Smoking Cessation Candidate Ganaxolone, Nicotine Patch - Smoking Cessation | Phase 2 | Completed | Jed E. Rose | 36 | 2013-06-01 | 2014-09-08 |
| Meclizine as a Potential Smoking Cessation Treatment Meclizine, Nicotine Patch, Placebo - Smoking Cessation | Phase 2 | Completed | Duke University | 146 | 2011-08-01 | 2014-08-01 |
Showing 20 of 27. Sign in to see all of them.
Smoking Cessation (15) · Tobacco Use Disorder (11) · Cigarette Smoking (9) · Smoking (4) · Tobacco Use Cessation (3) · Schizophrenia (2) · Tobacco Smoking (2) · Vaping (2) · Behavior, Addictive (1) · Bipolar Disorder (1) · Breast Neoplasms (1) · Depressive Disorder, Major (1) · Glucose Intolerance (1) · Hand-Foot Syndrome (1) · Health Education (1)
Duke University (4) · National Institute on Drug Abuse (NIDA) (3) · Jed E. Rose (2) · Rutgers, The State University of New Jersey (2) · The University of Texas Health Science Center, Houston (2) · University of Minnesota (2) · University of Oklahoma (2) · Centre for Addiction and Mental Health (1) · Chrono Therapeutics, Inc. (1) · Johns Hopkins University (1) · M.D. Anderson Cancer Center (1) · Maggie M Sweitzer, PhD (1) · Stanford University (1) · US Department of Veterans Affairs (1) · University of California, San Francisco (1)
United States (23) · Laos (2) · Canada (1) · South Africa (1)
Jed E Rose, Ph.D. (4) · Jed E. Rose, Ph.D. (2) · Luba Yammine, PhD (2) · Allen Wyler, MD (1) · Dorothy Hatsukami, Ph.D. (1) · Dorothy Hatsukami, PhD (1) · Eric C Westman, M.D. (1) · Eric T. Moolchan, M.D. (1) · Harry Lando, PhD (1) · Hilary A Tindle, MD, MPH (1) · Hope S. Rugo, MD (1) · James M Davis, M.D. (1) · Jennifer W. Tidey (1) · Joel D Killen, PhD (1) · Jonathan E Golub, PhD MPH (1)
PMID 23460656, PMID 23603206, PMID 25192771, PMID 30633744, PMID 31589323, PMID 33593332, PMID 33831213, PMID 34611902, PMID 37316311, PMID 38348917, PMID 38491559, PMID 38663460, PMID 40543725, PMID 40736921, PMID 40803048, PMID 42166710
P50DA027840 (5), R34DA043751 (2), K01CA160670 (1), K23DA039294 (1), R01CA118035 (1), R01CA239309 (1), R01DA025598 (1), R21CA253600 (1), U01CA261626 (1)