123 completed, 12 recruiting, 9 active not recruiting, 9 unknown. 53 Not applicable, 47 Phase 4, 27 Phase 2, 20 Phase 3, 16 Phase 1.
Follow Nicotine Patch: new trials by email Literature Review of Nicotine Patch trials Research Report on Nicotine Patch
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| iCanQuit Smoking Cessation Among Hispanic Adults iCanQuit Smartphone App Smoking Cessation Program, Nicotine Gum, Nicotine Patch - Cigarette Smoking-Related Carcinoma | Phase 3 | Not yet recruiting | Fred Hutchinson Cancer Center | 854 | 2026-12-01 | 2026-10-29 |
| Evaluation of Dependence and Nicotine Replacement Therapy-Supported Cessation Efforts Among Regular Electronic Cigarette Use Nicotine Replacement Therapies, Brief Behavioral Counseling - E Cigarette Use, Cessation, Tobacco | Phase 4 | Not yet recruiting | West Virginia University | 100 | 2026-09-01 | 2026-08-26 |
| My Path to Quit Tobacco Nicotine patch, Quitline Counseling Phone Calls, Counseling Sessions - Smoking Cessation | Phase 4 | Recruiting | University of Wisconsin, Madison | 1550 | 2026-07-06 | 2026-07-23 |
| Effect of Perioperative High-dose Transdermal Nicotine Patch on Pain Sensitivity Among Male Abstinent Tobacco Smokers Undergoing Thoracic Surgery: A Randomized Controlled Pilot Study Nicotine patch - Nicotine Dependence, Thoracic Diseases | Not applicable | Recruiting | Henan Provincial People's Hospital | 80 | 2025-11-30 | 2026-01-22 |
| Oral Nicotine Pouches Versus Nicotine Replacement Therapy to Reduce Cigarette Use for Smokers in Rural Appalachia Carbon Monoxide Measurement, Nicotine Lozenge, Oral Nicotine Pouch - Cigarette Smoking-Related Carcinoma | Not applicable | Recruiting | Ohio State University Comprehensive Cancer Center | 1000 | 2025-06-13 | 2026-06-30 |
| Beta-Adrenergic Modulation of Drug Cue Reactivity Propranolol, Nicotine Patch, Placebo Propranolol - Tobacco Use Disorder, Nicotine Dependence | Phase 4 | Recruiting | University of Oklahoma | 80 | 2024-11-26 | 2026-04-28 |
| PET Imaging Using the Tracer [18F]VAT to Assess the Antidepressant Effect of Nicotine. Nicotine transdermal patch, PET Scan with [18F] VAT - Major Depressive Disorder (MDD) | Phase 4 | Recruiting | Stony Brook University | 14 | 2024-10-03 | 2025-07-31 |
| The Avenues Study: Dual Use Cessation Varenicline, Nicotine patch, Dual Focused Cessation Counseling - Smoking Cessation, Electronic Cigarette Use | Phase 4 | Recruiting | University of Wisconsin, Madison | 500 | 2024-09-24 | 2026-10-07 |
| Adaptive Use of Nicotine Substitution to Maintain Smoking Reduction/Abstinence in Nicotine Responders Nicoderm, Nicorette 4Mg Chewing Gum, Nicorette Lozenge Product - Smoking Cessation, Harm Reduction | Phase 3 | Completed | Rose Research Center, LLC | 150 | 2024-08-29 | 2026-02-06 |
| Effectiveness of Different THR Products in Adult Population E-Cigarette, Nicotine patch - Smoking Cessation | Phase 3 | Unknown | Foundation for a Smoke Free World INC | 258 | 2024-06-01 | 2023-11-21 |
| Tobacco Treatment Comparison for Cancer Care Transdermal Nicotine Patch, Standard Telephone Counseling, Varenicline - Smoking Cessation, Cancer | Phase 4 | Completed | University of Wisconsin, Madison | 52 | 2024-03-01 | 2025-10-27 |
| Using Machine Learning to Develop Just-in-Time Adaptive Interventions for Smoking Cessation Android Wear smartwatch, Adaptive Treatment, Nicotine Patch - Smoking Cessation | Not applicable | Completed | The University of Texas Health Science Center, Houston | 60 | 2024-02-06 | 2025-03-28 |
| Community-based Smoking Cessation Treatment for Adults With High Stress Sensitivity. Aerobic Exercise, Counseling, Nicotine patch - Nicotine Dependence | Phase 3 | Recruiting | Jasper A. Smits | 360 | 2023-12-27 | 2026-05-15 |
| Evaluate Harm Reduction Products as a Second Line Intervention for Adult Smokers Who Do Not Quit With NRT Nicoderm, Nicorette 4Mg Chewing Gum, Nicorette Lozenge Product - Smoking Cessation, Harm Reduction | Phase 3 | Terminated | Rose Research Center, LLC | 4 | 2023-12-27 | 2025-03-30 |
| Evaluating Smoking Cessation Interventions for PWH in South Africa Varenicline, Nicotine patch, Nicotine gum - Smoking Cessation, HIV | Phase 2 / Phase 3 | Recruiting | Johns Hopkins University | 660 | 2023-11-27 | 2026-10-19 |
| Adapting and Evaluating a Tobacco Use Cessation Program for People Living With HIV in Uganda and Zambia Nicotine patch, text messaging - Nicotine Dependence, Tobacco Dependence | Phase 1 | Unknown | University of Southern California | 800 | 2023-09-13 | 2023-11-28 |
| Integrating Tobacco Use Cessation Into HIV Care and Treatment in Kisumu County, Kenya Tobacco Use Cessation Counselling Sessions, Bupropion, Nicotine patch - Tobacco Use Cessation, Tobacco Use | Phase 4 | Completed | University of California, San Francisco | 580 | 2023-05-16 | 2025-07-02 |
| Defining Neurobiological Links Between Substance Use and Mental Illness Placebo Nicotine Patch, Nicotine Patch - Major Depressive Disorder, Substance Use Disorder | Not applicable | Recruiting | National Institute on Drug Abuse (NIDA) | 620 | 2023-02-02 | 2026-11-03 |
| Ending Tobacco Use Through Interactive Tailored Messaging for Cambodian People Living With HIV/AIDS Smartphone-delivered Automated Messaging, Nicotine patch, Brief Advice to Quit and Smoking Cessation Self Help Materials - Smoking Cessation, HIV | Not applicable | Recruiting | H. Lee Moffitt Cancer Center and Research Institute | 800 | 2023-01-11 | 2026-08-13 |
| Exenatide for Smoking Cessation and Prevention of Weight Gain Exenatide 2 milligram (mg) Injection, Placebo, Nicotine patch - Smoking Cessation, Weight Gain | Phase 2 | Completed | The University of Texas Health Science Center, Houston | 140 | 2022-12-07 | 2026-03-23 |
Showing 20 of 166. Sign in to see all of them.
Smoking Cessation (86) · Tobacco Use Disorder (55) · Smoking (38) · Cigarette Smoking (18) · Tobacco Use Cessation (18) · Vaping (9) · Tobacco Smoking (8) · Schizophrenia (6) · Tobacco Use (6) · Acquired Immunodeficiency Syndrome (5) · Lung Neoplasms (4) · Mental Disorders (4) · Psychotic Disorders (4) · Uterine Cervical Neoplasms (4) · Carcinoma, Non-Small-Cell Lung (3)
University of Wisconsin, Madison (14) · Duke University (13) · M.D. Anderson Cancer Center (11) · Centre for Addiction and Mental Health (8) · H. Lee Moffitt Cancer Center and Research Institute (6) · National Institute on Drug Abuse (NIDA) (6) · McNeil AB (5) · The University of Texas Health Science Center, Houston (5) · University of California, San Francisco (5) · University of Oklahoma (5) · University of Houston (4) · Assistance Publique - Hôpitaux de Paris (3) · Rutgers, The State University of New Jersey (3) · University of Pennsylvania (3) · Yale University (3)
United States (127) · Canada (11) · France (4) · Germany (4) · China (2) · Laos (2) · Cambodia (1) · Czechia (1) · Hong Kong (1) · Kenya (1) · New Zealand (1) · Norway (1) · Pakistan (1) · South Africa (1) · Spain (1)
Jed E Rose, Ph.D. (5) · Elisabeth Kruse, PhD (4) · Andrew Pipe, MD (2) · Damon J Vidrine, Dr.PH (2) · Damon Vidrine, DrPH (2) · Francis J McClernon, Ph.D. (2) · Harry Lando, PhD (2) · Jasper Smits, PhD (2) · Jed E. Rose, Ph.D. (2) · Laurie Zawertailo, PhD (2) · Luba Yammine, PhD (2) · Megan E Piper, PhD (2) · Megan Piper, PhD (2) · Michael J Zvolensky, Ph.D. (2) · Peter Selby, MBBS (2)
PMID 37142273, PMID 37335995, PMID 34611902, PMID 39868569, PMID 37230961, PMID 12745503, PMID 18713921, PMID 19349630, PMID 19923530, PMID 20008701, PMID 20124230, PMID 20236788, PMID 20379614, PMID 20811658, PMID 21205047, PMID 21885891, PMID 22172440, PMID 22496918, PMID 22608375, PMID 22992296, PMID 23148822, PMID 23460656, PMID 23603206, PMID 23623506, PMID 23718718, PMID 23801018, PMID 23963055, PMID 24044880, PMID 24057996, PMID 24893290, PMID 24938369, PMID 25012994, PMID 25192771, PMID 25416755, PMID 25588294, PMID 25732567, PMID 25867447, PMID 26160457, PMID 26226536, PMID 26513517, PMID 26739730, PMID 26813210, PMID 28239942, PMID 28415979, PMID 28720080, PMID 28806908, PMID 29251951, PMID 29617633, PMID 29986268, PMID 30212849
P50DA027840 (5), 2005 (2), P50CA143188 (2), P50DA019706 (2), R01DA038442 (2), R01HL109031 (2), R34DA043751 (2), 1RC1CA144382-01 (1), 2014 (1), K01CA160670 (1), K23AT008442 (1), K23DA039294 (1), K24AA013736 (1), M01RR006192 (1), P01CA180945 (1)