12 completed, 2 recruiting, 2 terminated, 2 unknown. 20 Phase 3, 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 20 | Completed 12, Recruiting 2, Terminated 2, Unknown 2, Active not recruiting 1, Not yet recruiting 1 |
| Phase 2 | 5 | Completed 3, Recruiting 1, Terminated 1 |
Follow Nicotine Patch: new trials by email Literature Review of Nicotine Patch trials Research Report on Nicotine Patch
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| iCanQuit Smoking Cessation Among Hispanic Adults iCanQuit Smartphone App Smoking Cessation Program, Nicotine Gum, Nicotine Patch - Cigarette Smoking-Related Carcinoma | Phase 3 | Not yet recruiting | Fred Hutchinson Cancer Center | 854 | 2026-12-01 | 2026-10-29 |
| Adaptive Use of Nicotine Substitution to Maintain Smoking Reduction/Abstinence in Nicotine Responders Nicoderm, Nicorette 4Mg Chewing Gum, Nicorette Lozenge Product - Smoking Cessation, Harm Reduction | Phase 3 | Completed | Rose Research Center, LLC | 150 | 2024-08-29 | 2026-02-06 |
| Effectiveness of Different THR Products in Adult Population E-Cigarette, Nicotine patch - Smoking Cessation | Phase 3 | Unknown | Foundation for a Smoke Free World INC | 258 | 2024-06-01 | 2023-11-21 |
| Community-based Smoking Cessation Treatment for Adults With High Stress Sensitivity. Aerobic Exercise, Counseling, Nicotine patch - Nicotine Dependence | Phase 3 | Recruiting | Jasper A. Smits | 360 | 2023-12-27 | 2026-05-15 |
| Evaluate Harm Reduction Products as a Second Line Intervention for Adult Smokers Who Do Not Quit With NRT Nicoderm, Nicorette 4Mg Chewing Gum, Nicorette Lozenge Product - Smoking Cessation, Harm Reduction | Phase 3 | Terminated | Rose Research Center, LLC | 4 | 2023-12-27 | 2025-03-30 |
| Evaluating Smoking Cessation Interventions for PWH in South Africa Varenicline, Nicotine patch, Nicotine gum - Smoking Cessation, HIV | Phase 2 / Phase 3 | Recruiting | Johns Hopkins University | 660 | 2023-11-27 | 2026-10-19 |
| Efficacy of Nicotine in Preventing COVID-19 Infection Nicotine patch, Placebo patch - Covid19, SARS-Associated Coronavirus as Cause of Disease Classified Elsewhere | Phase 3 | Unknown | Assistance Publique - Hôpitaux de Paris | 1633 | 2020-10-22 | 2021-02-17 |
| Optimizing Tobacco Use Treatment for PLWHA Varenicline, Nicotine patch, Standard treatment - HIV/AIDS, Nicotine Dependence | Phase 3 | Active not recruiting | Abramson Cancer Center at Penn Medicine | 340 | 2020-02-17 | 2026-09-04 |
| Individualizing Pharmacotherapy for African American Smokers Nicotine patch, Varenicline Tartrate, Bupropion - Smoking Cessation | Phase 3 | Completed | University of Kansas Medical Center | 392 | 2019-05-01 | 2023-04-03 |
| PRecision Interventions for SMoking in the SCCS Nicotine patch, Varenicline, Nicotine metabolism - Tobacco Use Cessation | Phase 2 / Phase 3 | Completed | Vanderbilt University Medical Center | 67 | 2018-05-18 | 2020-06-01 |
| The Use of Nicotine Patches Together With E-cigarettes (With and Without Nicotine) for Smoking Cessation Nicotine patch, e-cigarette, Nicotine - Smoking Cessation | Phase 3 | Completed | University of Auckland, New Zealand | 1124 | 2016-03-01 | 2021-08-19 |
| Efficacy and Neural Correlates of Personalized Treatment With Transdermal Nicotine Replacement Nicotine patch, Nicotine mouthspray - Tobacco Use Disorder, Nicotine Dependence | Phase 2 / Phase 3 | Terminated | Centre for Addiction and Mental Health | 18 | 2015-07-01 | 2018-07-19 |
| Combination of Nicotine Replacement Therapy (NRT) and Varenicline to Increase Cessation of Tobacco (CONVICT Study) Nicotine Patch, Placebo, Varenicline - Tobacco Dependence, Smoking Cessation | Phase 3 | Completed | Queen Mary University of London | 117 | 2011-04-01 | 2012-10-11 |
| Pharmacogenetics of Nicotine Addiction Treatment Varenicline, Placebo, Transdermal Nicotine - Nicotine Addiction | Phase 3 | Completed | University of Pennsylvania | 1246 | 2010-12-01 | 2016-03-03 |
| Smoking Termination Enhancement Project (STEP) Cognitive Behavioral Treatment, Nicotine Patch, Wellness Program - Smoking | Phase 3 | Completed | Southern Methodist University | 150 | 2009-09-01 | 2016-02-04 |
| Telephone Counseling and the Distribution of Nicotine Patches to Smokers Nicotine Patch, Telephone Counseling, Placebo - Smoking Cessation | Phase 3 | Completed | University of California, San Diego | 4200 | 2009-02-01 | 2020-02-13 |
| Concurrent Nicotine Patch / Denicotinized Cigarette Therapy for Smoking Cessation II Nicotine Patch - Cigarette Smoking | Phase 3 | Completed | Duke University | 479 | 2007-08-01 | 2014-07-15 |
| Extended Cessation Treatment for Teen Smokers Extended treatment - Nicotine Dependence | Phase 2 / Phase 3 | Completed | Stanford University | 141 | 2006-09-01 | 2016-05-30 |
| Topiramate Alone and in Combination With the Nicotine Patch for Smoking Cessation: A Pilot Study Placebo (sugar pill), Topiramate, Nicotine patch - Tobacco Dependence | Phase 3 | Completed | UConn Health | 57 | 2006-04-01 | 2017-08-16 |
| Safety, Tolerability and Efficacy of the Nicotine Patch and Gum for the Treatment of Adolescent Tobacco Dependence Nicotine Patch, Nicotine Gum - Tobacco Dependence | Phase 2 / Phase 3 | Completed | National Institute on Drug Abuse (NIDA) | 157 | 1999-08-01 | 2017-01-12 |
Smoking Cessation (10) · Tobacco Use Disorder (9) · Smoking (3) · Cigarette Smoking (2) · Harm Reduction (2) · Tobacco Use Cessation (2) · Vaping (2) · Acquired Immunodeficiency Syndrome (1) · COVID-19 (1)
Rose Research Center, LLC (2) · Abramson Cancer Center at Penn Medicine (1) · Assistance Publique - Hôpitaux de Paris (1) · Centre for Addiction and Mental Health (1) · Duke University (1) · Foundation for a Smoke Free World INC (1) · Fred Hutchinson Cancer Center (1) · Jasper A. Smits (1) · Johns Hopkins University (1) · National Institute on Drug Abuse (NIDA) (1) · Queen Mary University of London (1) · Southern Methodist University (1) · Stanford University (1) · UConn Health (1) · University of Auckland, New Zealand (1)
United States (14) · Canada (2) · France (1) · New Zealand (1) · Pakistan (1) · South Africa (1) · United Kingdom (1)
Jasper Smits, PhD (2) · Al-Rehan A A Dhanji, MB BS BSc MRCS (1) · Caryn Lerman, PhD (1) · Cheryl A Oncken, MD (1) · Eric T. Moolchan, M.D. (1) · Hilary A Tindle, MD, MPH (1) · Jed E Rose, Ph.D. (1) · Joel D Killen, PhD (1) · Jonathan Bricker, PhD (1) · Jonathan E Golub, PhD MPH (1) · Laurie Zawertailo, PhD (1) · Madeeha Malik, PhD (1) · Maureen Sanderson, PhD, RD, MPH (1) · Michael Zvolensky, PhD (1) · Natalie Walker, PhD (1)
PMID 34611902, PMID 20379614, PMID 20811658, PMID 23148822, PMID 23460656, PMID 23718718, PMID 24057996, PMID 25012994, PMID 25588294, PMID 25732567, PMID 26513517, PMID 29986268, PMID 30614717, PMID 30946162, PMID 31502736, PMID 31515173, PMID 33300144, PMID 33713409, PMID 35639828, PMID 36387983, PMID 36789481, PMID 37142273, PMID 37338906, PMID 38369951, PMID 38491559, PMID 39868569, PMID 39976595, PMID 40174410, PMID 40358028, PMID 40543725
K24AA013736 (1), M01RR006192 (1), R01CA118035 (1), R01CA243914 (1), R01CA273221 (1), R01CA298383 (1), R01DA027533 (1), R01DA046576 (1), U01CA261626 (1), U01DA020830 (1)