4 completed, 4 unknown, 1 terminated. 9 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 9 | Completed 4, Unknown 4, Terminated 1 |
| Phase 2 | 3 | Completed 2, Terminated 1 |
Follow Cardiac Resynchronization Therapy: new trials by email Literature Review of Cardiac Resynchronization Therapy trials Research Report on Cardiac Resynchronization Therapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Tailoring Pacemaker Output to Physiology in Chronic Heart Failure Cardiac resynchronization therapy - Chronic Heart Failure | Phase 3 | Unknown | University of Leeds | 70 | 2020-02-01 | 2022-11-02 |
| Standard Care Versus Triventricular Pacing in Heart Failure Cardiac Resynchronisation Therapy - Heart Failure | Phase 3 | Unknown | Guy's and St Thomas' NHS Foundation Trust | 100 | 2015-08-01 | 2016-03-01 |
| Atrioventricular Junction Ablation and Biventricular Pacing for Atrial Fibrillation and Heart Failure AV junction ablation, CRT, Optimized drug therapy - Permanent Atrial Fibrillation | Phase 3 | Unknown | Centro Prevenzione Malattie Cardiovascolari N. e V. Corbella | 1830 | 2014-10-15 | 2021-01-20 |
| Echocardiography Guided Cardiac Resynchronization Therapy (EchoCRT) Implantable Cardioverter Defibrillator with Cardiac Resynchronization Therapy (BIOTRONIK Lumax HF-T CRT-D) - Heart Failure, Ventricular Dyssynchrony | Phase 2 / Phase 3 | Terminated | Biotronik, Inc. | 1680 | 2008-08-01 | 2018-01-17 |
| RESynchronisation in Patients With Heart Failure and a Normal QRS Duration Cardiac Resynchronization Pacing - Heart Failure, Congestive | Phase 3 | Completed | Heart of England NHS Trust | 60 | 2007-07-01 | 2017-02-28 |
| RethinQ Study - Evaluating Pacing in Heart Failure Patients Cardiac Resynchronization Therapy - Heart Failure | Phase 3 | Completed | Abbott Medical Devices | 250 | 2005-07-01 | 2019-02-04 |
| Comparison of Medical Therapy, Pacing and Defibrillation in Heart Failure Cardiac Resynchronization Therapy with & without defibrillator - Congestive Heart Failure | Phase 2 / Phase 3 | Completed | Boston Scientific Corporation | 2200 | 2000-01-01 | 2007-01-25 |
| Safety and Effectiveness of Cardiac Resynchronization Therapy With Defibrillation Cardiac Resynchronization Therapy with Defibrillation - Heart Failure, Congestive, Ventricular Fibrillation | Phase 2 / Phase 3 | Completed | Boston Scientific Corporation | 581 | 1998-02-01 | 2007-01-25 |
| Diastolic Ventricular Interaction and the Effects of Biventricular Pacing in Hypertrophic Cardiomyopathy Cardiac Resynchronisation Therapy - Hypertrophic Cardiomyopathy | Phase 3 | Unknown | University Hospital Birmingham | 32 | 2008-06-16 |
Heart Failure (7) · Atrial Fibrillation (1) · Cardiomyopathy, Hypertrophic (1) · Heart Diseases (1) · Tachycardia, Ventricular (1) · Ventricular Fibrillation (1)
Boston Scientific Corporation (2) · Abbott Medical Devices (1) · Biotronik, Inc. (1) · Centro Prevenzione Malattie Cardiovascolari N. e V. Corbella (1) · Guy's and St Thomas' NHS Foundation Trust (1) · Heart of England NHS Trust (1) · University Hospital Birmingham (1) · University of Leeds (1)
United Kingdom (5) · United States (4) · Italy (2) · Australia (1) · Austria (1) · Belgium (1) · Canada (1) · Czechia (1) · Denmark (1) · France (1) · Germany (1) · Israel (1) · Netherlands (1) · Poland (1) · Portugal (1)
Berthold Stegemann, PhD (1) · Claudio Marsano, MD (1) · Francisco Leyva, MD MB BS (1) · Frank Ruschitzka, MD (1) · Jagmeet Singh, MD (1) · Johannes Holzmeister, MD (1) · John Beshai, MD (1) · John Boehmer, MD (1) · Kiran Patel, PhD MRCP (1) · Klaus K Witte (1) · Leslie A Saxon, MD (1) · Paul W Foley, MB ChB MRCP (1) · Russell EA Smith, FRCP MD (1) · Steven Higgins, MD (1) · Teresa De Marco, MD (1)
PMID 14563591, PMID 15152059, PMID 17986493, PMID 19204305, PMID 21339317, PMID 21606084, PMID 23998714, PMID 27282848, PMID 29566816, PMID 29807890, PMID 30165479, PMID 34453840, PMID 35079787, PMID 35490339