13 completed, 3 recruiting, 3 terminated, 1 unknown. 20 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 20 | Completed 13, Recruiting 3, Terminated 3, Unknown 1 |
| Phase 2 | 2 | Completed 1, Unknown 1 |
Follow Capsaicin: new trials by email Literature Review of Capsaicin trials Research Report on Capsaicin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Analgesic Effectiveness of Capsaicin 8% Cutaneous Patch in Children Capsaicin 8% patch, Hydrocolloid dressing - Neuropathic Pain, Chronic Pain | Phase 3 | Recruiting | University Hospital, Brest | 46 | 2024-03-05 | 2026-06-15 |
| Study Evaluating the Analgesic Efficacy of Capsaicin 8% Patches in Chronic Coccygodynia. Capsaicin 179 Mg Cutaneous Patch, Capsaicin low concentration patch (capsaicin 0,04%, 3,2 mg/cm2) - Coccyx Disorder, Neuropathic Pain | Phase 3 | Recruiting | Nantes University Hospital | 188 | 2023-11-08 | 2026-10-09 |
| Capsaicin 179 mg Patch Versus Oral Duloxetine in Patients With Chemotherapy-induced Peripheral Neuropathy Capsaicin, Duloxetine - Chemotherapy-induced Peripheral Neuropathy | Phase 3 | Recruiting | Institut Cancerologie de l'Ouest | 274 | 2023-10-20 | 2026-03-31 |
| Comparison of Qutenza (8% Capsaicin) With a Low-dose Capsaicin for Treatment of Nerve Pain After Surgery Qutenza (capsaicin) 8% topical system, capsaicin 0.04% topical system - Post Surgical Neuropathic Pain | Phase 3 | Completed | Averitas Pharma, Inc. | 412 | 2021-07-13 | 2026-09-21 |
| Evaluation in the Treatment of Neuropathic Pain Post Breast Surgery Capsaicin, Pregabalin - Breast Cancer Patient | Phase 3 | Completed | Institut Cancerologie de l'Ouest | 140 | 2019-03-19 | 2026-05-05 |
| An Open-label, 8-week Safety, Efficacy, and Assessment of Cooling Methods for Administration of CNTX-4975-05 for Knee OA CNTX-4975-05, Lidocaine without epinephrine, ElastoGel - Knee Osteoarthritis | Phase 3 | Completed | Centrexion Therapeutics | 854 | 2018-09-18 | 2022-03-09 |
| Capsaicin Effect on Cytokines Profile in Dyslipidemia Capsaicin, Magnesia calcinada - Dyslipidemia, Overweight or Obesity | Phase 2 / Phase 3 | Unknown | University of Guadalajara | 17 | 2016-10-01 | 2016-07-19 |
| Efficacity of a Standardized Hypnotic Message During the Application of a Qutenza (Capsaicin) 8% Patch QUTENZA®, hypnotic message, music therapy - Pain | Phase 3 | Completed | Institut de Cancérologie de Lorraine | 69 | 2016-08-30 | 2022-04-07 |
| Capsaicin + Diclofenac Gel in Acute Back Pain or Neck Pain Diclofenac, Capsaicin, Placebo - Acute Pain | Phase 3 | Completed | Boehringer Ingelheim | 746 | 2016-05-09 | 2019-05-06 |
| Capsaicin Patches In Knee Osteoarthritis In Obese Patients capsaicin 8% patches (Qutenza), Placebo patches - Pain | Phase 3 | Terminated | Nadine ATTAL | 22 | 2015-07-01 | 2019-04-17 |
| Capsaicin Patch 8 % for the Treatment of Persistent Pain After Inguinal Herniotomy capsaicin patch (qutenza), Placebo - Persistent Pain After Inguinal Herniotomy | Phase 3 | Terminated | Copenhagen University Hospital, Rigshospitalet | 50 | 2012-08-01 | 2014-02-26 |
| A Study to Evaluate Efficacy and Safety of a Single Application of Capsaicin 8%Transdermal Delivery System Compared to Placebo in Reducing Pain Intensity in Subjects With Painful Diabetic Peripheral Neuropathy (PDPN) Capsaicin 8%, Placebo - Diabetic Peripheral Neuropathy, Pain | Phase 3 | Completed | Astellas Pharma Inc | 369 | 2012-02-01 | 2015-11-04 |
| A Study to Evaluate the Long-term Safety of Repeated QUTENZA Administration for Treatment of Pain Caused by Nerve Damage in Diabetic Patients QUTENZA - Painful Diabetic Peripheral Neuropathy (PDPN) | Phase 3 | Completed | Astellas Pharma Inc | 468 | 2011-11-01 | 2015-10-14 |
| Study With Two Capsaicin Topic Treatments in Diabetic Neuropathy. Capsaicin - Diabetic Neuropathy, Painful | Phase 3 | Completed | Arafarma Group, S.A. | 161 | 2010-11-04 | 2021-09-14 |
| Efficacy of Topical Capsaicin Cream for Stable Angina Capsaicin, Placebo cream - Stable Angina | Phase 3 | Terminated | Neal Weintraub | 7 | 2010-10-01 | 2015-06-25 |
| Efficacy and Safety Study of Topical Capsaicin in Painful Diabetic Neuropathy Capsaicin, placebo - Diabetic Polyneuropathy | Phase 2 / Phase 3 | Completed | Thammasat University | 33 | 2009-10-01 | 2012-05-09 |
| Study of NGX-4010 for the Treatment of Painful HIV-Associated Neuropathy NGX-4010, 8% capsaicin patch, 0.04% capsaicin patch - Pain, HIV Infections | Phase 3 | Completed | NeurogesX | 494 | 2006-06-01 | 2011-06-14 |
| Study of NGX-4010 for the Treatment of Postherpetic Neuralgia NGX-4010 - Peripheral Nervous System Diseases, Pain | Phase 3 | Completed | NeurogesX | 400 | 2006-03-01 | 2008-03-06 |
| Study of NGX-4010 for the Treatment of Postherpetic Neuralgia NGX-4010 - Peripheral Nervous System Diseases, Pain | Phase 3 | Completed | NeurogesX | 400 | 2005-06-01 | 2008-03-06 |
| Capsaicin Lozenges in Treating Patients With Mucositis Caused by Radiation Therapy capsaicin, placebo, radiation therapy - Head and Neck Cancer, Radiation Toxicity | Phase 3 | Completed | Alliance for Clinical Trials in Oncology | 18 | 1998-10-01 | 2016-07-13 |
Pain (7) · Neuralgia (6) · Peripheral Nervous System Diseases (3) · Diabetic Neuropathies (2) · Herpes Zoster (2) · Neuralgia, Postherpetic (2) · Obesity (2) · Osteoarthritis, Knee (2) · Acute Pain (1) · Angina, Stable (1) · Chronic Pain (1) · Dyslipidemias (1) · HIV Infections (1) · Head and Neck Neoplasms (1) · Neuritis (1)
NeurogesX (3) · Astellas Pharma Inc (2) · Institut Cancerologie de l'Ouest (2) · Alliance for Clinical Trials in Oncology (1) · Arafarma Group, S.A. (1) · Averitas Pharma, Inc. (1) · Boehringer Ingelheim (1) · Centrexion Therapeutics (1) · Copenhagen University Hospital, Rigshospitalet (1) · Institut de Cancérologie de Lorraine (1) · Nadine ATTAL (1) · Nantes University Hospital (1) · Neal Weintraub (1) · Thammasat University (1) · University Hospital, Brest (1)
France (8) · United States (5) · Germany (2) · Netherlands (2) · Poland (2) · Russia (2) · Spain (2) · United Kingdom (2) · Belgium (1) · Czechia (1) · Denmark (1) · Italy (1) · Thailand (1) · Ukraine (1)
Jeffrey Tobias, MD (2) · Claire Carette (1) · Dr. Raffaelle Carraro (1) · Ernesto J Ramirez Lizardo, PhD (1) · Faisal M Khan, MD (1) · Kongkiat Kulkantrakorn, MD (1) · Randall M. Stevens, MD (1) · Scott Okuno, MD (1)
PMID 18977178, PMID 21087403, PMID 22067661, PMID 23351618, PMID 25290151, PMID 27746370, PMID 27919222, PMID 32221866, PMID 34044838
2009 (1), 2015 (1)