20 completed, 2 unknown, 2 withdrawn, 1 terminated. 25 Phase 2, 6 Phase 1, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 25 | Completed 20, Unknown 2, Withdrawn 2, Terminated 1 |
| Phase 1 | 6 | Completed 6 |
| Phase 3 | 2 | Completed 1, Unknown 1 |
Follow Capsaicin: new trials by email Literature Review of Capsaicin trials Research Report on Capsaicin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Serratus Plane Block (SPB) Versus Capsaïcine Versus Botox-A for Chronic Neuropathic Pain in Post-mastectomy Syndrome Capsaicin 8% Patch, Serratus Plane Block, Botulinum Toxin A - Post-Mastectomy Neuropathic Pain Syndrome | Phase 2 | Withdrawn | Centre Oscar Lambret | 2025-06-10 | 2026-10-06 | |
| Capsaicin for Cerebral Perfusion Augmentation Capsaicin - Cerebral Circulatory Disorder | Phase 2 | Completed | Instituto Mexicano del Seguro Social | 20 | 2022-09-20 | 2023-03-14 |
| Capsaicin for Post-stroke Dysphagia Capsaicin 1% oral solution, InOrpha Solution - Dysphagia, Late Effect of Stroke | Phase 2 | Unknown | Georg Kägi, MD | 82 | 2021-08-24 | 2023-06-22 |
| Study to Evaluate the Interest of Qutenza in Patients With Head and Neck Cancer in Remission and With Sequelae Neuropathic Pain. Capsaïcin patch (Qutenza®), Amitriptyline (Laroxyl®) - Head and Neck Cancer | Phase 2 | Completed | Institut Claudius Regaud | 13 | 2021-04-28 | 2026-04-14 |
| Capsaicin to Prevent Delayed Chemotherapy Induced Nausea and Vomiting (CapCIN) Capsaicin, Placebo - Chemotherapy-induced Nausea and Vomiting | Phase 2 | Completed | Christian Medical College, Vellore, India | 160 | 2019-10-18 | 2022-05-20 |
| Influence on Cough and Airway Symptoms by Oral Capsaicin Capsicum Oleoresin, Placebos - Cough | Phase 2 | Completed | Vastra Gotaland Region | 55 | 2019-06-01 | 2026-09-01 |
| A Phase 2 Clinical Trial Examining the Effects on Osteoarthritic Knee Pain of CGS-200-1, CGS-200-5 and Vehicle Control CGS-200-1, CGS-200-5, CGS-200 Vehicle - Osteoarthritis, Knee, Pain | Phase 2 | Completed | Propella Therapeutics | 122 | 2018-05-14 | 2024-10-30 |
| Topical Capsaicin for Cyclical Vomiting Capsaicin 0.1% Cream, Placebos - Cyclical Vomiting | Phase 2 | Completed | Henry Ford Health System | 30 | 2017-12-20 | 2021-12-15 |
| Clinical Trial Assessing the Efficacy of Capsaicin Patch (Qutenza®) in Cancer Patients With Neuropathic Pain Qutenza - Neuropathic Pain | Phase 2 | Completed | Centre Hospitalier Universitaire de Saint Etienne | 84 | 2017-11-09 | 2022-02-08 |
| Normal Breathing and Swallowing in Healthy Volunteers Capsaicin, Videofluoroscopic swallow study - Healthy | Phase 1 / Phase 2 | Completed | University of Florida | 49 | 2017-05-23 | 2021-01-14 |
| Capsaicin Effect on Cytokines Profile in Dyslipidemia Capsaicin, Magnesia calcinada - Dyslipidemia, Overweight or Obesity | Phase 2 / Phase 3 | Unknown | University of Guadalajara | 17 | 2016-10-01 | 2016-07-19 |
| Effects of High-concentration Topical Capsaicin on Histaminergic and Non-histaminergic Itch Capsaicin 24 Hours, Capsaicin 1 Hour, Qutenza Demo Patch - Pruritus | Phase 1 / Phase 2 | Completed | Hjalte Holm Andersen | 16 | 2016-05-01 | 2016-11-22 |
| Respiratory Kinematics of Cough in Healthy Older Adults and Parkinson's Disease Capsaicin, Voluntary cough test - Cough, Parkinson's Disease | Phase 1 / Phase 2 | Completed | University of Florida | 44 | 2014-10-01 | 2017-03-24 |
| Intranasal Capsaicin Treatment for Non-Allergic Irritant Rhinitis Capsaicin, Placebo - Nonallergic Irritant Rhinitis | Phase 2 | Completed | The University of Texas Health Science Center, Houston | 22 | 2014-10-01 | 2020-08-17 |
| Respiratory Kinematics During Voluntary and Reflex Cough in Healthy Adults Healthy adults who receive capsaicin - Cough | Phase 1 / Phase 2 | Completed | University of Florida | 25 | 2013-05-01 | 2022-02-09 |
| Qutenza®-Remodulin® in Pulmonary Arterial Hypertension Patients Qutenza, Tegaderm - Pulmonary Hypertension, Pain | Phase 2 | Completed | Imperial College London | 11 | 2011-08-01 | 2023-10-05 |
| Cough and Swallow Rehab Following Stroke Expiratory muscle strength training, Placebo expiratory training, Measures performed on all subjects - Ischemic Stroke | Phase 1 / Phase 2 | Completed | University of Florida | 14 | 2011-01-01 | 2017-01-27 |
| The Qutenza Patch as Treatment for Disabling Treprostinil (Remodulin) Infusion Site Pain Qutenza (8% capsaicin) - Pulmonary Hypertension, Pulmonary Arterial Hypertension | Phase 2 | Completed | University of Rochester | 6 | 2010-11-01 | 2016-04-21 |
| Trial to Evaluate the Efficacy of Topical Capsaicin to Reduce Pain and Improve Health-related Quality of Life in Adults With Chronic Myofascial Neck Pain Capsaicin, Placebo - Myofascial Pain Syndrome | Phase 2 | Withdrawn | Stamford Hospital | 2009-11-01 | 2016-12-06 | |
| Efficacy and Safety Study of Topical Capsaicin in Painful Diabetic Neuropathy Capsaicin, placebo - Diabetic Polyneuropathy | Phase 2 / Phase 3 | Completed | Thammasat University | 33 | 2009-10-01 | 2012-05-09 |
Showing 20 of 25. Sign in to see all of them.
Cough (4) · Pain (4) · Neuralgia (3) · Acute Pain (2) · Agnosia (2) · Deglutition Disorders (2) · Hypertension, Pulmonary (2) · Stroke (2) · Breast Neoplasms (1) · Cerebrovascular Disorders (1) · Cystitis, Interstitial (1) · Diabetic Neuropathies (1) · Dyslipidemias (1) · Facial Pain (1) · Familial cyclic vomiting syndrome (1)
University of Florida (4) · National Institute of Dental and Craniofacial Research (NIDCR) (2) · Centre Hospitalier Universitaire de Saint Etienne (1) · Centre Oscar Lambret (1) · Christian Medical College, Vellore, India (1) · Georg Kägi, MD (1) · Henry Ford Health System (1) · Hjalte Holm Andersen (1) · Imperial College London (1) · Institut Claudius Regaud (1) · Instituto Mexicano del Seguro Social (1) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (1) · NeurogesX (1) · Propella Therapeutics (1) · Stamford Hospital (1)
United States (14) · France (3) · Denmark (1) · India (1) · Mexico (1) · Sweden (1) · Switzerland (1) · Thailand (1) · United Kingdom (1)
Alexandra E. Brandimore, M.A. (1) · Alexandra E. Brandimore, M.A. CCC/SLP (1) · Amber U Luong, MD, PhD (1) · Emily Plowman, PhD (1) · Ernesto J Ramirez Lizardo, PhD (1) · Eva Millqvist, MD, PhD (1) · Heber Rew Bright, MPharm (1) · Hugh Flood (1) · James C. Eisenach, M.D. (1) · Joseph Miller, MD (1) · Juan M Marquez-Romero, MD, MSc (1) · Karen W Hegland, PHD (1) · Karen W. Hegland, Ph.D. (1)
PMID 22182397, PMID 24062200, PMID 27130637, PMID 38905580, PMID 42548348
2016 (1), 2017 (1), R01DK049524 (1)