15 completed. 15 Phase 1, 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 15 | Completed 15 |
| Phase 2 | 5 | Completed 5 |
Follow Wound Infection: new trials by email Literature Review of Wound Infection trials Research Report on Wound Infection
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Red Light Photobiomodulation and Topical Disinfectants Methylene Blue Only, Chlorhexidine Gluconate Only, Methylene Blue + Chlorhexidine Gluconate - Healthcare Associated Infection, Nosocomial Infection | Phase 1 / Phase 2 | Completed | Ondine Biomedical Inc. | 28 | 2023-01-10 | 2023-04-04 |
| Tebipenem (SPR994) Tissue Penetration in Diabetic Patients With Wound Infections and Healthy Volunteers Via In Vivo Microdialysis Tebipenem Pivoxil Hydrobromide - Diabetes, Wound Infection | Phase 1 | Completed | Hartford Hospital | 12 | 2021-07-01 | 2023-10-23 |
| Chlorhexidine Vaginal Preparation for Reduction of Post-cesarean Endometritis and Sepsis Chlorhexidine Gluconate vaginal solution 0.05% - Postpartum Endometritis, Wound Infection | Phase 1 / Phase 2 | Completed | Zagazig University | 840 | 2020-05-15 | 2022-09-23 |
| Omadacycline Tissue Penetration in Diabetic Patients With Wound Infections and Healthy Volunteers Via In Vivo Microdialysis Omadacycline, Microdialysis Catheter Insertion - Diabetes, Wound Infection | Phase 1 | Completed | Hartford Hospital | 14 | 2020-02-10 | 2021-08-25 |
| Pharmacokinetic Study of Vancomycin, Clindamycin And/or Gentamicin Administration During Surgery Using a Microdialysis Procedure Blood and microdialysis samples - Surgical Site Infection | Phase 1 | Completed | Poitiers University Hospital | 25 | 2019-05-26 | 2025-01-16 |
| Prophylactic Antibiotics After Cesarean Cephalexin, Placebo, Metronidazole - Surgical Site Infection | Phase 1 | Completed | The University of Texas Medical Branch, Galveston | 321 | 2017-08-01 | 2023-08-16 |
| Tedizolid Tissue Penetration in Diabetic Patients With Wound Infections and Healthy Volunteers Via In Vivo Microdialysis Tedizolid, Microdialysis Catheter Insertion - Diabetes, Wound Infection | Phase 1 | Completed | Hartford Hospital | 18 | 2016-02-23 | 2019-01-15 |
| Tissue Penetration of Ceftolozane/Tazobactam in Diabetic Patients With Lower Limb Infections Ceftolozane/tazobactam, Microdialysis Catheter Insertion - Diabetes, Wound Infection | Phase 1 | Completed | Hartford Hospital | 16 | 2016-02-19 | 2019-01-15 |
| Safety Study to Evaluate the Contact Sensitizing Potential of Topically Applied ZuraPrep™ and ZuraPrep™ Without IPA Chloraprep, 0.9% Physiological Saline, ZuraPrep without IPA - Surgical Site Infection | Phase 1 | Completed | Zurex Pharma, Inc. | 208 | 2014-07-01 | 2015-03-17 |
| Safety Study to Evaluate the Cumulative Irritation Potential of Topically Applied ZuraPrep™ and ZuraPrep™ Without IPA ChloraPrep, 0.1% Sodium Lauryl Sulfate, 0.9% Physiological Saline - Surgical Site Infection | Phase 1 | Completed | Zurex Pharma, Inc. | 40 | 2014-06-01 | 2014-10-27 |
| DFA-02 in Patients Undergoing Colorectal Surgery DFA-02, Placebo - Surgical Site Infection | Phase 1 / Phase 2 | Completed | Dr. Reddy's Laboratories Limited | 30 | 2012-02-01 | 2014-09-01 |
| Tumescent Antibiotic Delivery Pharmacokinetics Tumescent Antibiotic Delivery of cefazolin with or without metronidazole, Intravenous Antibiotic Delivery - Prevention of Surgical Site Infections | Phase 1 | Completed | Klein, Jeffrey A., M.D. | 4 | 2009-03-01 | 2011-09-28 |
| A Comparison Of The 3M TM S Surgical Skin Closure System To The Standard Vicryl Suture Closure of Sternotomy Incisions During Cardiac Surgery Vicryl Suture, 3M TM S Surgical Skin Closure System - Wound Infection | Phase 1 | Completed | American Heart Association | 36 | 2007-09-01 | 2012-07-18 |
| Study of the Efficacy of Plain Soap and Water Versus Alcohol-based Rubs for Surgical Hand Preparation Plain soap and water (PSW), Alcohol-based hand rub (ABHR) - Postoperative Wound Infection | Phase 1 / Phase 2 | Completed | University Hospital, Geneva | 3317 | 2007-01-01 | 2012-08-21 |
| StrataGraft™ Skin Tissue (Human Donor Skin) In The Surgical Management Of Complex Skin Defects StrataGraft Skin Tissue, Cadaver allograft - Third Degree Burn, Burns | Phase 1 / Phase 2 | Completed | Stratatech, a Mallinckrodt Company | 15 | 2006-07-01 | 2019-10-16 |
Surgical Wound Infection (8) · Diabetes Mellitus (4) · Burns (1) · Cross Infection (1) · Degloving Injuries (1)
Infections (15) · Pathologic Processes (8) · Pathological Conditions, Signs and Symptoms (8) · Postoperative Complications (8) · Endocrine System Diseases (4) · Glucose Metabolism Disorders (4) · Metabolic Diseases (4) · Nutritional and Metabolic Diseases (4) · Disease Attributes (1) · Iatrogenic Disease (1) · Soft Tissue Injuries (1) · Wounds and Injuries (1)
Ethanol (2) · Metronidazole (2) · chlorhexidine gluconate (2) · citrate, isopropyl alcohol, methylene blue, parabens drug combination (2) · 2-Propanol (1) · Blood Specimen Collection (1) · Cefazolin (1) · Cephalexin (1) · Sodium Dodecyl Sulfate (1) · Water (1) · ceftolozane, tazobactam drug combination (1) · omadacycline (1) · tedizolid (1) · tedizolid phosphate (1)
Hartford Hospital (4) · Zurex Pharma, Inc. (2) · American Heart Association (1) · Dr. Reddy's Laboratories Limited (1) · Klein, Jeffrey A., M.D. (1) · Ondine Biomedical Inc. (1) · Poitiers University Hospital (1) · Stratatech, a Mallinckrodt Company (1) · The University of Texas Medical Branch, Galveston (1) · University Hospital, Geneva (1) · Zagazig University (1)
United States (12) · France (1) · Kenya (1) · Saudi Arabia (1)
David P Nicolau, PharmD (3) · Ahmed Shafiek (1) · Antonio F Saad, MD (1) · Esther Campbell (1) · Harold L Lazar MD (1) · Hytham Atia (1) · Kent Allenby, MD (1) · Maggie Butler, PhD (1) · Peter M Nthumba, MD (1) · Tomefa E Asempa, PharmD (1)
PMID 19276766, PMID 20878941, PMID 21475006, PMID 21554389, PMID 22297835, PMID 27313846, PMID 28893779, PMID 40403315
R44AR047499 (1)