23 unknown, 19 completed, 5 recruiting, 4 terminated. 40 Not applicable, 5 Phase 2, 4 Phase 3, 2 Phase 1, 2 Phase 4.
Follow Wound Complication: new trials by email Literature Review of Wound Complication trials Research Report on Wound Complication
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Use of Tranexamic Acid in Decreasing Wound Complication in Total Ankle Replacement. Transexamic acid, Normal Saline (0.9% NaCl) - Ankle Arthritis, Wound Complication | Phase 2 | Not yet recruiting | Ottawa Hospital Research Institute | 40 | 2026-12-01 | 2026-10-22 |
| Prophylactic Subcutaneous Drainage After Gynecologic Oncology Midline Laparotomy Prophylactic subcutaneous closed-suction drainage, Standard closure without subcutaneous drainage - Wound Complication, Surgical Site Infection (SSI) | Not applicable | Recruiting | Mahmut Yassa | 334 | 2026-07-20 | 2026-07-30 |
| Using WoundPilot to Support Wound Care Decisions in Patients With Chronic Wounds WoundPilot - Wound Complication, Wound Care | Not applicable | Not yet recruiting | University Ghent | 40 | 2026-06-01 | 2026-05-01 |
| Sarcoma Surgery Wound Complications Comparing Usual Versus Negative Pressure Dressing Negative Pressure Wound Therapy (NPWT) Dressings, Standard Absorbent Dressings - Sarcoma, Negative Pressure Therapy | Phase 2 | Not yet recruiting | NHS Greater Glasgow and Clyde | 94 | 2025-12-01 | 2025-07-09 |
| Advanced Cutaneous Evaluator (ACE): Estimation of Clinical and Economic Impact Advanced Cutaneous Evaluator (ACE), Control (non-ACE) - Wounds and Injuries, Wound Complication | Not applicable | Completed | Fundacin Biomedica Galicia Sur | 73 | 2025-03-26 | 2025-12-10 |
| Incisional Negative Pressure Wound Therapy to Reduce Infection and Complications in High-Risk Fractures Incisional Negative Pressure Wound Therapy (NPWT) - Fracture of Tibia, Wound Heal | Phase 3 | Recruiting | Major Extremity Trauma Research Consortium | 352 | 2025-01-01 | 2026-05-12 |
| Cosmetic Outcome of Electrocautery, Scalpel and PEAK PlasmaBlade for Surgical Breast Incisions Scalpel and standard electrocautery or PEAK PlasmaBlade, PEAK PlasmaBlade, Standard Electrocautery - Wound Complication, Surgical Wound Infection | Not applicable | Recruiting | University of British Columbia | 186 | 2024-12-09 | 2024-12-16 |
| Effectiveness of Topical Vancomycin in Reducing Sternal Wound Infections Post-Cardiac Surgery while Group B (vancomycin group, n=12) had vancomycin powder applied during closure. T - Wound Complication, Cardiac Surgery | Phase 1 / Phase 2 | Unknown | Liaquat National Hospital & Medical College | 24 | 2024-11-01 | 2024-10-28 |
| Morbidity of Conventional and No-touch Saphenectomy in Coronary Artery Bypass Grafting. Conventional Saphenous vein harvest, No touch Saphenous vein harvest - Saphenectomy, No Touch | Not applicable | Unknown | Instituto Nacional de Cirugia Cardiaca, Uruguay | 52 | 2024-03-15 | 2024-07-11 |
| Comparing Wound Complication Following TMA With Aid of Electrospun Fiber Matrix Synthetic electrospun fiber matrix - Amputation, Wound; Foot | Not applicable | Unknown | Scripps Health | 40 | 2024-03-01 | 2024-03-05 |
| Short Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds Wound; Head, Multiple, Wound; Head, Scalp | Unknown | Dufresne, Craig, MD, PC | 20 | 2023-09-20 | 2022-06-16 | |
| Prineo Sensitivity Dressing Study Prineo dressing - Allergic Reaction, Wound Complication | Phase 4 | Completed | Rush University Medical Center | 303 | 2023-08-17 | 2026-07-10 |
| Wound Healing in Primary TKA Skin closure using skin adhesive, Skin closure without skin adhesive - Total Knee Replacement, Wound Complication | Not applicable | Unknown | Rothman Institute Orthopaedics | 216 | 2023-08-16 | 2023-08-23 |
| EvaLuating negAtive pressUre Wound theRapy in brEast coNserving Surgery Negative pressure wound therapy - Breast Cancer, Seroma | Not applicable | Unknown | Zuyderland Medisch Centrum | 300 | 2023-05-01 | 2023-07-07 |
| Topical Insulin for Postoperative Wound Healing Insulin, Povidone-Iodine - Wound Complication, Insulin Resistance, Diabetes | Not applicable | Unknown | Cairo University | 74 | 2023-04-16 | 2024-08-21 |
| Hip DAA Closure Techniques wound closure subcuticular running stitch using 3-0 monocryl suture without skin adhesive, wound closure subcuticular running stitch using 3-0 monocryl suture with two layers of skin adhesive - Total Hip Replacement, Wound Complication | Not applicable | Unknown | Rothman Institute Orthopaedics | 172 | 2023-03-01 | 2023-08-23 |
| MetaMet: Bone Cutter Versus Bone Saw for Ray Amputation Bone Saw, Bone Cutter - Diabetic Foot, Gangrene; Limb | Not applicable | Unknown | University College Hospital Galway | 40 | 2023-01-01 | 2023-04-07 |
| NEgative prEssure Wound Therapy in Renal Transplant NWPT group - Transplant Complication, Renal Transplant | Phase 4 | Recruiting | Centro Hospitalar De São João, E.P.E. | 150 | 2023-01-01 | 2025-07-15 |
| Axillary Versus Primary Breast Approach for Second-stage Breast Reconstruction implant exchange operation - Breast Neoplasm Female, Breast Reconstruction | Not applicable | Unknown | Second Affiliated Hospital, Zhejiang University, School of Medicine | 136 | 2022-12-01 | 2022-10-31 |
| Long Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds Wounds and Injuries, Wound Infection | Unknown | Dufresne, Craig, MD, PC | 20 | 2022-09-10 | 2022-06-16 |
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Wound Infection (13) · Surgical Wound Infection (11) · Wounds and Injuries (9) · Surgical Wound (5) · Breast Neoplasms (4) · Infections (4) · Inflammation (4) · Seroma (4) · Obesity (3) · Pain, Postoperative (3) · Cicatrix (2) · Coronary Artery Disease (2) · Hematoma (2) · Incisional Hernia (2) · Obesity, Morbid (2)
Pathological Conditions, Signs and Symptoms (26) · Pathologic Processes (23) · Infections (21) · Postoperative Complications (14) · Neoplasms (8) · Wound Infection (8) · Nutritional and Metabolic Diseases (7) · Signs and Symptoms (7) · Neoplasms by Site (6) · Nutrition Disorders (5) · Skin Diseases (5) · Skin and Connective Tissue Diseases (5) · Body Weight (4) · Breast Diseases (4) · Endocrine System Diseases (4)
Negative-Pressure Wound Therapy (4) · Bandages (2) · Ascorbic Acid (1) · Control Groups (1) · Drainage (1) · Early Ambulation (1) · Electrocoagulation (1) · Insulin (1) · Laser Therapy (1) · Povidone-Iodine (1) · Saline Solution (1) · Tissue Adhesives (1)
Zuyderland Medisch Centrum (3) · Dufresne, Craig, MD, PC (2) · Rothman Institute Orthopaedics (2) · The University of Texas Health Science Center, Houston (2) · University of British Columbia (2) · American University of Beirut Medical Center (1) · Azienda Ospedaliera, Ospedale Civile di Legnano (1) · Benazir Bhutto Hospital, Rawalpindi (1) · Cairo University (1) · Centro Hospitalar De São João, E.P.E. (1) · Changi General Hospital (1) · Columbia University (1) · Dr. J. Werier (1) · Endeavor Health (1) · Fundacin Biomedica Galicia Sur (1)
United States (20) · Canada (6) · Netherlands (3) · Pakistan (3) · Ireland (2) · Taiwan (2) · Turkey (Türkiye) (2) · Australia (1) · Belgium (1) · China (1) · Denmark (1) · Egypt (1) · Lebanon (1) · Portugal (1) · Singapore (1)
Craig R Dufresne, MD (2) · Beth Plunkett, MD (1) · Bradley Meulenkamp, MD MSc FRCSC (1) · Carl J Brown, MD MSc FRCSC (1) · Carol K Dingee, MD, FRCSC (1) · Caroline C Marrs, MD (1) · Celeste Durnwald, MD (1) · Chao-Shun Lin, PhD (1) · Chung-May Yang, MD (1) · Daniel J Del Gaizo, MD (1) · Dimitri Beeckman, PhD (1) · Eman Sbaity, MD (1) · Hans Ravn, MD PhD (1) · Hilde Beele, PhD (1)
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