9 completed, 4 terminated, 3 recruiting, 3 unknown. 13 Not applicable, 3 Phase 4, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 13 | Completed 7, Recruiting 2, Terminated 2, Unknown 1, Withdrawn 1 |
| Phase 4 | 3 | Completed 1, Terminated 1, Unknown 1 |
| Phase 1 | 1 | Recruiting 1 |
| Phase 3 | 1 | Completed 1 |
Follow Tissue Adhesives: new trials by email Literature Review of Tissue Adhesives trials Research Report on Tissue Adhesives
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Tissue Adhesive Glue Modified Cyanoacrylate (Glubran® 2) in Soft Pancreas Pancreaticojejunostomy with Modified N-Butyl-2-Cyanoacrylate (Glubran® 2), Standard(duct-to-mucosa) Pancreaticojejunostomy - Pancreatic Cancer, Periampullary Cancer | Not applicable | Recruiting | Minia University | 194 | 2025-09-15 | 2026-10-01 |
| Saleh's Technique for Pancreaticojejunostomy (Pancreatic Parenchymal Injection of N-butyl-2-cyanoacrylate) Pancreatic parenchymal injection of N-butyl-2-cyanoacrylate(Histoacryl®) - Pancreaticoduodenectomy, Postoperative Pancreatic Fistula | Phase 1 | Recruiting | Minia University | 30 | 2025-08-25 | 2026-09-11 |
| Tissue Adhesive Versus Sutures in Oral Biopsy Closure Tissue adhesive (PeriAcryl 90 HV), Surgical suture (Nylon 4-0) - Mouth Neoplasms | Not applicable | Recruiting | Damascus University | 28 | 2025-08-12 | 2026-06-18 |
| 3M™ Topical Tissue Adhesive Versus Commercially Available Tissue Adhesive for the Closure of Lacerations and Incisions 3M Topical Tissue Adhesive, Histoacryl® Blue Topical Skin Adhesive - Trauma-related Wound, Surgical Incision | Terminated | Solventum US LLC | 78 | 2024-10-28 | 2026-07-27 | |
| Cosmetic Outcomes With Tissue Adhesive (2-octylcyanoacrylate) or Staples in Repeated Cesarean Section Staples, Tissue adhesive - Cesarean Section | Not applicable | Completed | Università degli Studi dell'Insubria | 80 | 2020-05-15 | 2021-09-08 |
| Cyanoacrylate With Sutures for Fixation of Free Gingival Graft cyanoacrylate tissue adhesive beside sutures - Soft Tissue Atrophy | Not applicable | Unknown | Cairo University | 10 | 2019-09-16 | 2019-08-21 |
| Skin Closure With Tissue Adhesives vs. Subcuticular Suture After Robotic Urogynecologic Procedures Subcuticular Skin Closure, Tissue Adhesives - Surgical Wound, Tissue Adhesion | Not applicable | Completed | St. John Hospital & Medical Center | 47 | 2018-03-20 | 2019-04-04 |
| Tissue Adhesive in Hip and Knee Arthroplasty, A Cost -Effectiveness Analysis Tissue adhesive in primary Total Hip and Total Knee arthroplasty - Hip Osteoarthritis, Knee Osteoarthritis | Unknown | Amphia Hospital | 980 | 2017-01-23 | 2017-06-12 | |
| Tissue Adhesive vs. Sterile Strips After Cesarean Delivery Tissue Adhesive, Sterile strips - Wound Complication, Complications; Cesarean Section | Not applicable | Terminated | Endeavor Health | 504 | 2016-11-01 | 2019-08-14 |
| Closure Techniques and Scar Appearance Running polypropylene closure, Tissue Adhesive (Derma-Bond), Subcuticular polyglactin-910 combined with tissue adhesive - Wound Closure Techniques | Not applicable | Withdrawn | Northwestern University | 2016-07-01 | 2021-12-06 | |
| Trial Investigating Cyanoacrylate Glue to Prevent Surgical Site Infection Following Breast Surgery 2-Octyl Cyanoacrylate Glue - Surgical Wound Infection | Phase 4 | Unknown | Ottawa Hospital Research Institute | 30 | 2016-06-01 | 2016-05-20 |
| Tissue Adhaesive in Wound Closure Following Primary Total Knee Arthroplasty tissue adhesive (Leukosan®) - Total Knee Arthroplasty, Infection | Not applicable | Completed | Hvidovre University Hospital | 30 | 2015-09-01 | 2019-01-25 |
| Unicirc vs Open Surgical Circumcision Unicirc with tissue adhesive, Open Surgical - Circumcision, Male | Phase 4 | Completed | Simunye Primary Health Care | 75 | 2015-04-01 | 2018-10-03 |
| Rapid, Minimally-invasive Voluntary Adult Male Circumcision Surgical Control, Unicirc with tissue adhesive - Circumcision | Not applicable | Completed | Simunye Primary Health Care | 100 | 2013-10-01 | 2018-10-02 |
| Cosmetic Outcome Study of Lid Laceration Repair With Suture Versus Tissue Adhesive Tissue Adhesive skin closure, Absorbable suture skin closure, Non-absorbable suture skin closure - Eyelid Laceration | Phase 4 | Terminated | The University of Texas Health Science Center, Houston | 4 | 2013-08-01 | 2014-12-03 |
| A Randomized Controlled Trial of Open Surgical vs. Rapid, Minimally-invasive Voluntary Adult Male Circumcision Open surgical circumcision, Unicirc device with tissue adhesive - Circumcision | Not applicable | Completed | Simunye Primary Health Care | 150 | 2013-06-01 | 2018-10-02 |
| A Randomized Controlled Trial of Open Surgical vs. Minimally-invasive Voluntary Adult Male Circumcision Gomco Clamp with Tissue Adhesive, Open surgical circumcision - Surgical Technique | Not applicable | Completed | Universidade Católica de Moçambique | 200 | 2012-08-01 | 2013-09-10 |
| Comparison Study of Wound Closure at Time of Cesarean Delivery: Dermabond Glue Versus Surgical Staples Surgical skin staples, Dermabond - Cesarean Section | Not applicable | Terminated | University of Massachusetts, Worcester | 136 | 2007-09-01 | 2013-03-05 |
| Randomized Controlled Trial Comparing Different Closure Methods for Laparoscopic Port Sites Tissue adhesive - Laparoscopic Cosmesis | Not applicable | Completed | New York Presbyterian Hospital | 20 | 2007-03-01 | 2007-04-27 |
| Evaluation of Fibrin Sealant 2 in Retroperitoneal or Intra-Abdominal Surgery Fibrin Sealant 2 (FS2), Oxidized Regenerated Cellulose (Surgicel) - Blood Loss, Surgical | Phase 3 | Completed | Ethicon, Inc. | 135 | 2006-02-01 | 2009-01-09 |
Lacerations (2) · Pancreatic Neoplasms (2) · Surgical Wound (2) · Wounds and Injuries (2) · Anastomotic Leak (1) · Bile Duct Neoplasms (1) · Blood Loss, Surgical (1) · Cholangiocarcinoma (1) · Duodenal Neoplasms (1) · Infections (1) · Mouth Neoplasms (1) · Osteoarthritis, Hip (1) · Osteoarthritis, Knee (1) · Surgical Wound Infection (1) · Tissue Adhesions (1)
Simunye Primary Health Care (3) · Minia University (2) · Amphia Hospital (1) · Cairo University (1) · Damascus University (1) · Endeavor Health (1) · Ethicon, Inc. (1) · Hvidovre University Hospital (1) · New York Presbyterian Hospital (1) · Northwestern University (1) · Ottawa Hospital Research Institute (1) · Solventum US LLC (1) · St. John Hospital & Medical Center (1) · The University of Texas Health Science Center, Houston (1) · Universidade Católica de Moçambique (1)
United States (5) · South Africa (3) · Egypt (2) · Italy (1) · Mozambique (1) · Netherlands (1) · Syria (1)
Saleh K Saleh, MD (2) · Antonella Cromi, M.D., Ph.D. (1) · Beth Plunkett, MD (1) · Dawn S Tasillo, MD (1) · Fabio Ghezzi, M.D. (1) · Giuseppe Del Priore (1) · James Hart, MD (1) · Judianne Kellaway, MD (1) · Lena Braginsky, MD (1) · Murad Alam, MD (1) · Norman Goldstuck, MB ChB (1) · Peter Millard, MD, PhD (1) · Peter S Millard, MD, PhD (1) · Rutger van Geenen, MD, PhD (1)
PMID 27299735, PMID 28040257, PMID 31306319, PMID 35183000, PMID 40127250