19 completed. 19 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 19 | Completed 19 |
Follow Vision Disorders: new trials by email Literature Review of Vision Disorders trials Research Report on Vision Disorders
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Post Marketing Study to Evaluate the Safety and Effectiveness of Brolucizumab in Patients With Diabetic Macular Edema. brolucizumab - Diabetic Macular Edema | Phase 4 | Completed | Novartis Pharmaceuticals | 66 | 2024-12-11 | 2026-04-13 |
| MIRAGE Study: Clinical Outcomes of the Mamba Sirolimus-Eluting PTCA Balloon Mamba Sirolimus-Eluting PTCA Balloon, Percutaneous Coronary Angioplasty with Sirolimus-Coated Balloon - Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD)) | Phase 4 | Completed | Frisch Medical Device Private Limited | 360 | 2023-01-11 | 2026-03-11 |
| Safety and Tolerability Study of Daily Dosing Rimegepant in Episodic Migraine Prevention Rimegepant - Migraine, Episodic Migraine | Phase 4 | Completed | Pfizer | 441 | 2022-03-15 | 2025-09-03 |
| Study to Evaluate the Safety and Effectiveness of Intravitreal Injections (IVI) of Brolucizumab in Patients With Neovascular Age-related Macular Degeneration (nAMD) Injection Brolucizumab - Neovascular Age-related Macular Degeneration (nAMD) | Phase 4 | Completed | Novartis Pharmaceuticals | 105 | 2022-03-09 | 2025-03-20 |
| Study of Innovative Multimodal Imaging Biomarkers to Predict Anatomical Outcome in Naive Patients With wAMD Treated With Brolucizumab. Brolucizumab - Neovascular Age-related Macular Degeneration | Phase 4 | Completed | Novartis Pharmaceuticals | 122 | 2021-10-15 | 2025-05-16 |
| Efficacy and Safety of Two Different Brolucizumab 6 mg Dosing Regimens in Neovascular Age-related Macular Degeneration Brolucizumab - Age-related Macular Degeneration | Phase 4 | Completed | Novartis Pharmaceuticals | 52 | 2021-07-13 | 2025-09-26 |
| Study of Efficacy of Ranibizumab in Different Regimens in Patients With Diabetic Macula Edema ranibizumab 0.5 mg - Diabetic Retinopathy | Phase 4 | Completed | Novartis Pharmaceuticals | 135 | 2015-02-23 | 2019-01-04 |
| Safety and Efficacy of Switching From Aflibercept to Ranibizumab in Patients With nAMD Ranibizumab - Neovascular Age-related Macular Degeneration | Phase 4 | Completed | Novartis Pharmaceuticals | 103 | 2014-08-28 | 2019-02-15 |
| Study of the Effectiveness of Ozurdex for the Control of Uveitis Dexamethasone pellet - Uveitis, Intermediate, Uveitis, Posterior | Phase 4 | Completed | Johns Hopkins University | 20 | 2014-01-01 | 2019-07-05 |
| Efficacy and Safety of Ranibizumab 0.5 mg Administered as Two Alternative Dosing Regimens in Chinese Patients With nAMD (Age Related Macular Degeneration) Ranibizumab - Neovascular Age-related Macular Degeneration | Phase 4 | Completed | Novartis Pharmaceuticals | 332 | 2013-02-22 | 2019-09-04 |
| Combining Donepezil With Perceptual Learning in Normal and Amblyopic Human The Effect of Donepezil on Perceptual Learning in Adult Amblyopia Donepezil, Single-letter training, Uncrowd training - Amblyopia | Phase 4 | Completed | Dennis Levi | 20 | 2012-05-01 | 2019-01-17 |
| Extension Study to Compare Long-term Efficacy and Safety of Ranibizumab Intravitreal Injections Versus Dexamethasone Intravitreal Implant in Patients With RVO RFB002, Dexamethasone - Retinal Vein Occlusion | Phase 4 | Completed | Novartis Pharmaceuticals | 175 | 2012-05-01 | 2016-05-17 |
| Intraoperative Dexamethasone Implant Improves Outcome of Cataract Surgery With Diabetic Macular Edema Dexamethasone Drug delivery system (Ozurdex), Cataract surgery - Macular Edema, Cystoid, Vision Disorders | Phase 4 | Completed | Post Graduate Institute of Medical Education and Research, Chandigarh | 20 | 2011-05-01 | 2014-06-18 |
| A Clinical Study in Current Medical Practice of the Efficacy and Safety of Ranibizumab 0.5mg in Diabetic Patients Presenting a Visual Impairment Due to Macular Edema Ranibizumab - Visual Impairment, Macular Edema | Phase 4 | Completed | Novartis Pharmaceuticals | 394 | 2011-02-01 | 2017-02-23 |
| Project Magnify - A Comparison of Two Strategies to Improve Reading Ability Optical Aids - Vision, Low | Phase 4 | Completed | Medical University of South Carolina | 20 | 2005-05-01 | 2007-10-03 |
| Trial Comparing Daily Atropine Versus Weekend Atropine Atropine - Amblyopia | Phase 4 | Completed | Jaeb Center for Health Research | 168 | 2002-06-01 | 2010-03-25 |
| Healthy Volunteer Study of Sildenafil Effects Upon Vision Sildenafil - Blindness | Phase 4 | Completed | University of Cambridge | 2002-02-01 | 2005-11-10 | |
| Tinnitus Treatment by Structured Cognitive Behavioral Therapy Cognitive behavioral therapy, Waiting group - Tinnitus | Phase 4 | Completed | University Hospital Tuebingen | 286 | 2000-10-01 | 2008-07-22 |
| A Study of Interventions to Reduce Disability From Visual Loss in Nursing Home Residents Visual impairment intervention program - Cataract, Refractive Error | Phase 4 | Completed | Johns Hopkins University | 2544 | 1999-06-01 | 2017-10-06 |
Macular Degeneration (6) · Geographic Atrophy (5) · Wet Macular Degeneration (5) · Choroidal Neovascularization (4) · Macular Edema (4) · Eye Diseases (3) · Vision, Low (3) · Amblyopia (2) · Cataract (2) · Color Vision Defects (2) · Retinal Degeneration (2) · Retinal Diseases (2) · Retinal Vein Occlusion (2) · Angina Pectoris (1)
Nervous System Diseases (19) · Neurologic Manifestations (19) · Pathological Conditions, Signs and Symptoms (19) · Sensation Disorders (19) · Signs and Symptoms (18) · Eye Diseases (16) · Retinal Diseases (8) · Retinal Degeneration (7) · Pathologic Processes (6) · Uveal Diseases (5) · Cardiovascular Diseases (4) · Choroid Diseases (4) · Eye Diseases, Hereditary (4) · Metaplasia (4)
Ranibizumab (4) · brolucizumab (3) · Atropine (1) · Calcium Dobesilate (1) · Cataract Extraction (1) · Cognitive Behavioral Therapy (1) · Dexamethasone (1) · Donepezil (1) · Phacoemulsification (1) · Sildenafil Citrate (1) · rimegepant sulfate (1)
Novartis Pharmaceuticals (9) · Johns Hopkins University (2) · Dennis Levi (1) · Frisch Medical Device Private Limited (1) · Jaeb Center for Health Research (1) · Medical University of South Carolina (1) · Pfizer (1) · Post Graduate Institute of Medical Education and Research, Chandigarh (1) · University Hospital Tuebingen (1) · University of Cambridge (1)
United States (6) · Germany (5) · India (3) · Burma (1) · China (1) · France (1) · Italy (1) · Malaysia (1) · Switzerland (1) · United Kingdom (1)
Amod Gupta, MBBS MS (1) · Bhavin Oza (1) · Dennis M Levi, OD, PhD (1) · Hans P. Zenner, M.D. (1) · Jagat Ram, MBBS MS (1) · Jennifer E Thorne, MD, PhD (1) · John Mollon, FRS (1) · Jonathan M Holmes, MD (1) · Michael X Repka, MD (1) · Morris J Brown, MD (1) · Sheila West (1) · Stephen Morse, MD (1)
PMID 11297486, PMID 12967792, PMID 15522375, PMID 16286622, PMID 16353397, PMID 17188044, PMID 17675159, PMID 1850220, PMID 1922252, PMID 19365036, PMID 19592101, PMID 20110127, PMID 20451898, PMID 21907115, PMID 22108357, PMID 22264944, PMID 22559899, PMID 22801846, PMID 23245386, PMID 23287811, PMID 28824369, PMID 30986442, PMID 31383649, PMID 32107066, PMID 35188581, PMID 40833455, PMID 41366286, PMID 6208888
2014 (2), 2019 (1), R01AG015812 (1), U10EY011751 (1)